A5084305097- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Parasites and Host Interactions
- Autopsy Techniques and Outcomes
- Viral Infections and Vectors
- Blood properties and coagulation
- Salmonella and Campylobacter epidemiology
- Heme Oxygenase-1 and Carbon Monoxide
- Dermatological diseases and infestations
- COVID-19 and healthcare impacts
- Dermatological and COVID-19 studies
- Diverse Scientific Research Studies
- Erythrocyte Function and Pathophysiology
- Mineral Processing and Grinding
- Mining Techniques and Economics
- Blood groups and transfusion
- Drilling and Well Engineering
- Child Nutrition and Water Access
Kwame Nkrumah University of Science and Technology
2017-2025
Ebonyi State University
2023
University of Mines and Technology
2021
Kumasi Centre for Collaborative Research in Tropical Medicine
2017
Background/Objectives: The COVID-19 pandemic has significantly impacted global health. However, Africa reported relatively low numbers of cases and fatalities. Although the largely receded, reasons for its milder course on African continent have not yet been fully clarified. This study explored hypothesis that helminth co-infections may contributed to these observations. Methods: A retrospective cohort was conducted using 104 plasma samples collected during third wave in Ashanti Region...
Background: Several studies have linked coronavirus disease 2019 (COVID-19) risk to age and ABO blood groups. Variations in plasma angiotensin-converting enzyme 2 (ACE2) levels counts been reported, suggesting an association between severity low lymphocyte levels. Aim: this study aimed understand how these factors relate COVID-19 Ghanaian patients, considering geographical demographic differences. Methods: Participants were recruited from six hospitals Kumasi, Ghana, June 2020 July 2021....
Abstract Background and Aims Children with sickle cell disease (SCD) have an increased risk of multiple hemotransfusions this can predispose them to elevated iron stores. The objectives the study were determine extent stores associated factors in a population steady‐state SCD children Ghana. Methods This cross‐sectional was conducted at pediatric clinic Komfo Anokye Teaching Hospital. Complete blood count serum ferritin assay performed for ( n = 178) children. Descriptive multivariate...
Introduction Sickle cell disease is highly prevalent in Africa with a significant public health burden. Nonetheless, morbidity and mortality sickle that result from the progression of organ damage not well understood. The Organ Damage Cell Disease Study (ORDISS) designed as longitudinal cohort study to provide critical insight into cellular molecular pathogenesis chronic for development future innovative treatment. Methods analysis ORDISS aims recruit children aged 0–15 years who attend...
Abstract Background and Aims Hemolysis is a fundamental feature of sickle cell disease (SCD) contributing to the vaso‐occlusive crisis patients. The objectives study were assess link between hemolysis proteins hematological parameters, validate cystatin C (CYS C) as potent renal marker in diagnoising SCD. Method Here, cross‐sectional carried out at pediatric SCD clinic Komfo Anokye Teaching Hospital comprised 90 children (HbSC, HbSF, HbSS). ANOVA, t ‐test, Spearman's rank correlation...
Individuals with COVID-19 experience thrombotic events probably due to the associated hypofibrinolysis resulting from upregulation of plasminogen activator inhibitor-1 (PAI-1) antigen. This study evaluated plasma PAI-1 antigen levels and haematological parameters before treatment after recovery severe in Ghana.This cross-sectional was conducted at Sunyani Regional Hospital, recruited 51 patients who had RT-PCR-confirmed SARS-CoV-2. Participants' sociodemographic data clinical characteristics...
<h3>Background</h3> Salmonella are a group of facultative anaerobic bacteria that belong to the family Enterobacteriaceae. The common serovars enterica subsp. serovar Typhi which causes typhoid fever and non-typhoidal Salmonellae (NTS) associated with gastroenteritis. Data on epidemiology genomic characteristics in sub-Saharan African countries limited. This study describes characterization Ghana. <h3>Methods</h3> A prospective incidental hospital-based surveillance among patients presenting...
Background: Disturbance in naturally-occurring anticoagulants may contribute to the hypercoagulable state COVID-19. This study determined plasma antigen levels of protein C (PC), S (PS), antithrombin-III (AT-III), and thrombomodulin (TM) before treatment after recovery from Materials Methods: cross-sectional study, conducted February August 2022 at Kumasi South Hospital, recruited sixty-five RT-PCR-confirmed COVID-19 participants. A venous blood sample was taken for full count (FBC) analysis...
The objective of this research is to establish the importance Sample Repeatability Index (SRI) as a measure ensure error minimisation in exploration drilling protocols, during sample preparation prospect areas. Almost all stages entailed involve sampling. Samples collected and prepared within field are well checked for good Quality Assurance Control (QA/QC) methods. However, samples sent out testing laboratory outside not under control team, hence must be taken assess efficiency accuracy...