A5050657405- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Blood Coagulation and Thrombosis Mechanisms
- Blood properties and coagulation
- Dermatological and COVID-19 studies
- Child Nutrition and Water Access
- Pregnancy and preeclampsia studies
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Maternal and fetal healthcare
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
Komfo Anokye Teaching Hospital
2020-2023
Preeclampsia (PE) is associated with endothelial injury and hemostatic abnormalities. However, the diagnostic role of coagulation parameters natural anticoagulants in predicting PE has not been explored Ghana. This study assessed plasma levels these factors as surrogate markers its subtypes. case–control included 90 women (cases) normotensive pregnant (controls). Blood samples were drawn for estimation complete blood count tests. The prothrombin time (PT), activated partial thromboplastin...
Abstract Background and Aims Children with sickle cell disease (SCD) have an increased risk of multiple hemotransfusions this can predispose them to elevated iron stores. The objectives the study were determine extent stores associated factors in a population steady‐state SCD children Ghana. Methods This cross‐sectional was conducted at pediatric clinic Komfo Anokye Teaching Hospital. Complete blood count serum ferritin assay performed for ( n = 178) children. Descriptive multivariate...
Sickle Cell Anaemia (SCA) is associated with a hypercoagulable state resulting in predisposition to venous thromboembolism. With improvements the quality of care, more patients SCA survive into adulthood an increase frequency end-organ damage and chronic complications such as leg ulcers (CLUs). These rarely occur first decade life are recurrent, painful, slow-to-heal. This study tested hypothesis that coagulation enhanced CLU. 145 participants (50 CLU, 50 without 45 haemoglobin AA) were...
Abstract Background and Aims Hemolysis is a fundamental feature of sickle cell disease (SCD) contributing to the vaso‐occlusive crisis patients. The objectives study were assess link between hemolysis proteins hematological parameters, validate cystatin C (CYS C) as potent renal marker in diagnoising SCD. Method Here, cross‐sectional carried out at pediatric SCD clinic Komfo Anokye Teaching Hospital comprised 90 children (HbSC, HbSF, HbSS). ANOVA, t ‐test, Spearman's rank correlation...
Blood cell abnormalities may occur among COVID-19 patients and could be detrimental during the disease’s progression. This study assessed complete blood count (CBC) parameters determined abnormal changes in peripheral of receiving care at Komfo Anokye Teaching Hospital (KATH), Ghana. hospital-based descriptive cross-sectional conducted KATH, Kumasi, Ghana, recruited seventy-three (73) RT-PCR-confirmed participants. Venous was taken from participants into EDTA tubes used for CBC analyses...