- Diabetes, Cardiovascular Risks, and Lipoproteins
- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Cardiovascular Health and Risk Factors
- Obesity, Physical Activity, Diet
- Hemoglobinopathies and Related Disorders
- Iron Metabolism and Disorders
- Maternal and fetal healthcare
- Liver Disease Diagnosis and Treatment
- Diabetes Management and Research
- Blood Pressure and Hypertension Studies
- Gestational Diabetes Research and Management
- Reproductive Health and Technologies
- Artificial Intelligence in Healthcare
- Health and Lifestyle Studies
- Global Public Health Policies and Epidemiology
- Global Maternal and Child Health
- Ovarian function and disorders
- Diabetes Management and Education
- HIV-related health complications and treatments
- Diabetes Treatment and Management
- Lipoproteins and Cardiovascular Health
- Child Nutrition and Water Access
- Hepatitis B Virus Studies
- Hepatitis C virus research
Kwame Nkrumah University of Science and Technology
2016-2025
Edith Cowan University
2017-2025
Kwame Nkrumah University
2021-2024
University of Science and Technology
2020-2023
Korea University of Science and Technology
2023
Kumasi Centre for Collaborative Research in Tropical Medicine
2023
Garden City University College
2020-2023
University Research Co (United States)
2023
University of Ghana
2023
Shantou University Medical College
2020
First two decades of the twenty-first century are characterised by epidemics non-communicable diseases such as many hundreds millions patients diagnosed with cardiovascular and type 2 diabetes mellitus, breast, lung, liver prostate malignancies, neurological, sleep, mood eye disorders, amongst others. Consequent socio-economic burden is tremendous. Unprecedented decrease in age maladaptive individuals has been reported. The absolute majority expanding disorders carry a chronic character,...
Gestational hypertension (GH) and Preeclampsia, (PE) are the most complicated amongst hypertensive disorders of pregnancy. The mechanism that links in pregnancy to adverse maternal outcomes is not fully understood though some relate this endothelial dysfunction originating from an imbalanced angiogenic regulators oxidative stress biomarkers. This study assessed correlation between biomarker levels with among GH PE participants.A cohort pregnant women who received antenatal care at Obstetrics...
Diabetes mellitus (DM) appears to be a global epidemic and an increasingly major non-communicable disease threatening both affluent non-affluent society. The study aimed determine the knowledge of diabetic complications among diabetes clients visiting Diabetic Clinical at Sampa Government Hospital, Ghana.
Hypertensive disorders of pregnancy are important causes morbidity and mortality. The levels calcium (Ca2+) magnesium (Mg2+) in may implicate their possible role pregnancy-induced hypertension. This study assessed serum Ca2+ Mg2+ women with PIH (pregnancy-induced hypertension) PE (pre-eclampsia), compared to that normal pregnancy. case–control was conducted on 380 pregnant (≥20 weeks gestation) receiving antenatal care at three hospitals the Cape Coast metropolis, Ghana. comprised 120 PIH,...
Obesity and hypertension are public health problems associated with cardiovascular events worldwide. Bus drivers, whose lifestyle is primarily sedentary characterized by poor eating habits at increased risk. This study determined the prevalence lifestyle-related risk factors of obesity among Inter-Regional Metromass Drivers (IRMBDs) in Ghana. cross-sectional recruited 527 professional drivers from stations Accra Kumasi Metropolis, Structured questionnaires were administered to obtain...
Abstract Background Obesity is a classified risk factor for several of the world’s leading causes death. In this study, we combined information contained in body mass index (BMI), total percentage fat (TPBF) and relative (RFM) to estimate obesity prevalence examine factors associated with obesity. Methods The study recruited 1027 undergraduate students aged between 16 25 years using cross-sectional design two-stage stratified random sampling January April 2019 from Kwame Nkrumah University...
Aim To characterize clinically relevant subgroups of patients with type-2 diabetes mellitus (T2DM) based on adiposity, insulin secretion, and resistance indices. Methods A cross-sectional study was conducted at Eastern Regional Hospital in Ghana from July to October 2021 investigate long-term T2DM. select participants, a systematic random sampling method employed. Demographic data collected using structured questionnaire fasting blood samples were taken measure glycemic lipid levels. Blood...
Background: Preeclampsia is responsible for a significant rate of maternal morbidity and mortality worldwide. Gestational age as risk factor has impact on fetal outcomes in pregnancies affected by preeclampsia. However, to our knowledge, no study identified the gestational age–specific prevalence preeclampsia Ghana. Thus, this ascertained well its associated factors. Methods: A hospital‐based retrospective observational was conducted reviewing data collected from birth register 619 pregnant...
There is a surge in chronic diseases the developing world, driven by high prevalence of cardio-metabolic risk factors. This study described differences obesity and factors between urban rural settlements Ashanti Region Ghana. comparative cross-sectional included 672 participants (median age 50 years), which 312 were from Kumasi (urban) 360 Jachie-Pramso (rural). Demographic, anthropometric other gathered venous blood samples drawn for biochemical assays. Results suggested significant...
This study aimed to determine the knowledge and prevalence of obesity among Ghanaian newly diagnosed type 2 diabetics. cross-sectional was conducted Structured questionnaire used obtain data. Anthropometric measurements fasting blood sugar levels were also assessed. Participants had adequate about general concept (72.0%) method weight measurement (98.6%) but less knowledgeable ideal body (4.2%). The commonly known cause, complication, management poor diet (76.9%), hypertension (81.8%),...
Glycated hemoglobin (HbA1c), owing to its ability reflect glycemia over a relatively longer time span, is still been investigated as an adjunct test for fasting plasma glucose (FPG) identify subjects at risk of metabolic syndrome (MetS) in some Caucasian populations. However, whether or not HbA1c can serve FPG the definition MetS Ghanaian population remains unknown. This study determined prevalence and evaluated ≥ 5.6% 5.6 mmol/l glycemic component among non-diabetic Ghana. was case–control...
Visceral obesity and insulin resistance contribute to developing cardiometabolic syndrome (MetS). We investigated the predictive abilities of lipid accumulation product (LAP), waist circumference-triglyceride index (WTI), triglyceride-glucose (TyG) for MetS screening among general Ghanaian adults.
Background Advanced maternal age (AMA) has been associated with negative pregnancy outcomes. Oxidative stress (OS) and defective placental dysfunction are contributing factors. This study determined the association between AMA adverse outcomes, OS biomarkers angiogenic growth mediators (AGMs) in normal pregnancies. Methods prospective cohort conducted at Obstetrics Gynaecology (O&G) Department of Komfo Anokye Teaching Hospital (KATH) finally included 175 pregnant women comprising, 58 (35–45...
Background. The World Health Organization (WHO) recommends the use of Insecticide Treated Bed-Nets and Intermittent Preventive Treatment (IPT) with Sulphadoxine-Pyrimethamine (SP) as interventions in curbing malaria during pregnancy. However, increasing evidence shows a gap coverage where not all pregnant women receive recommended SP dose. This study evaluated factors influencing uptake IPTp-SP among Kumasi, Ghana. Methodology. cross-sectional was conducted 280 attending Kwame Nkrumah...
Optimal oxidative stress (OS) is important throughout pregnancy; however, an increased OS may alter placental angiogenesis culminating in imbalanced of angiogenic growth mediators (AGMs). Suboptimal Health Status (SHS), a physical state between health and disease, be associated with unbalanced AGMs. In this study, we explored the association SHS, biomarkers (BOS) AGMs among normotensive pregnant women (NTN-PW) Ghanaian Cohort Study (GHOACS). This comparative GHOACS recruited 593 NTN-PW from...
Suboptimal health status (SHS) is a reversible state between ideal and illness it can be effectively reversed by risk prediction, disease prevention, personalized medicine under the global background of predictive, preventive, (PPPM) concepts. More more Chinese nurses have been troubled psychological symptoms (PS). The correlation PS SHS unclear in nurses. purpose current study to investigate prevalence relationship along with predisposing factors as well discuss feasibility improving...
Gestational diabetes mellitus (GDM) is a global public health issue that have serious consequences on mother and her child's health. However, limited data available the prevalence of GDM its associated risk factors in Ghana. This study investigated among women attending selected antenatal clinics Kumasi, cross-sectional included 200 pregnant who attended from Three-selected facilities Ashanti Region, Women already diagnosed were identified through their medical records confirmed based...
Cardiometabolic syndrome (MetS) is closely linked to type 2 diabetes mellitus (T2DM) and the leading cause of complications. Anthropometric indices could be used as a cheap approach identify MetS among T2DM patients. We determined prevalence its association with sociodemographic anthropometric patients in tertiary hospital Ashanti region Ghana. A comparative cross-sectional study was conducted 241 outpatients attending Komfo Anokye Teaching Hospital (KATH) Kumasi South for routine check-up....
Colorectal cancer (CRC) is one of the commonest cancers associated with diverse prognosis times in different parts world. Despite medical interventions, overall clinical outcomes and survival remains very poor for most patients developing countries. This study therefore investigated rate colorectal its prognostic factors among at Komfo Anokye Teaching Hospital, Ghana.In this retrospective cohort study, a total 221 diagnosed CRC from 2009 to 2015 Surgical Oncological units Hospital (KATH),...
This study determined noncompliance to antihypertensive therapy (AHT) and its associated factors in a Ghanaian population by using the health belief model (HBM). descriptive cross-sectional conducted at Kintampo Municipality Ghana recruited total of 678 hypertensive patients. The questionnaire constituted information regarding sociodemographics, five-Likert type HBM questionnaire, lifestyle-related factors. rate AHT this was 58.6%. mean age (SD) participants 43.5 (±5.2) years median duration...
Abstract Background The Suboptimal Health Status Questionnaire-25 (SHS-Q-25) developed to measure has been used worldwide, but its construct validity only tested in the Chinese population. Applying Structural Equation Modelling, we investigate aspects of SHS-Q-25 determine interactions between SHS subscales a Ghanaian Methods study involved healthy participants (n = 263; aged 20–80 years; 63% female), who responded SHSQ-25. In an exploratory factor and parallel analysis, extracted new domain...
Preeclampsia is a leading cause of foeto-maternal deaths especially in Sub-Saharan Africa. However, the prevalence and risk factors preeclampsia are scarce Central region Ghana with previous study assessing individual independent factors. This determined algorithm adverse preeclampsia.This multi-centre prospective cross-sectional was conducted from October 2021 to 2022 at Mercy Women's Catholic Hospital Fynba Health Centre region, Ghana. A total 1,259 pregnant women were randomly sampled...