A5033745380- Cardiac Health and Mental Health
- Ferroptosis and cancer prognosis
- Health, psychology, and well-being
- MicroRNA in disease regulation
- Kruppel-like factors research
- Mental Health Treatment and Access
- Inflammatory Biomarkers in Disease Prognosis
- Circular RNAs in diseases
- Cardiovascular Health and Risk Factors
- Gut microbiota and health
- Fibroblast Growth Factor Research
- Ubiquitin and proteasome pathways
- Cardiovascular Function and Risk Factors
- Autophagy in Disease and Therapy
- Endoplasmic Reticulum Stress and Disease
- RNA modifications and cancer
- Congenital Diaphragmatic Hernia Studies
Shantou University
2020-2024
First Affiliated Hospital of Shantou University Medical College
2020-2024
Background. Diabetes mellitus (DM) can induce cardiomyocyte injury and lead to diabetic cardiomyopathy (DCM) which presently has no specific treatments consequently increase risk of mortality. Objective. To characterize the therapeutic effect 6-gingerol (6-G) on DCM identify its potential mechanism. Methods. In vivo streptozotocin- (STZ-) induced DM model was established by using a high-fat diet STZ, followed low-dose (25 mg/kg) high-dose (75 6-G intervention. For an in vitro model, H9c2 rat...
Recent investigations have proposed a potential causal association between the occurrence of ferroptosis, nuclear factor kappa B (NF-κB) and ubiquitin-specific protease 24 (USP24). Nevertheless, mechanism USP24 NF-κB regulation ferroptosis in context diabetic cardiomyopathy (DCM) remain unclear. In this study, high-fat diet streptozotocin-induced mouse DCM model were established, high glucose palmitic acid treatment H9c2 cells neonatal primary cardiomyocytes (NMPCs) was used as an vitro...
Abstract Background The gut microbiota is involved in the pathogenesis of diabetic cardiomyopathy (DCM). Myricetin protects cardiac function DCM. However, low bioavailability myricetin fails to explain its pharmacological mechanisms thoroughly. Research has shown that a positive effect on microbiota. We hypothesize improves development DCM via regulating Methods mice were induced with streptozotocin and fed high-fat diet, then treated by gavage diet for 16 weeks. Indexes related composition,...
Suboptimal health status (SHS) is a reversible state between ideal and illness it can be effectively reversed by risk prediction, disease prevention, personalized medicine under the global background of predictive, preventive, (PPPM) concepts. More more Chinese nurses have been troubled psychological symptoms (PS). The correlation PS SHS unclear in nurses. purpose current study to investigate prevalence relationship along with predisposing factors as well discuss feasibility improving...
Recent studies of fibroblast growth factor 21 (FGF21), first recognized as a regulator glucose and lipid metabolism, have found that the level in serum FGF21 is associated with prognosis many cardiovascular diseases, but its relationship to acute heart failure (AHF) patients remains unknown. Our study aimed investigate whether circulating could predict short-term AHF patients.Four hundred two 19 healthy controls were recruited into prospective cohort study, blood samples participants...