A5066906828- Pregnancy and preeclampsia studies
- Global Maternal and Child Health
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Maternal and fetal healthcare
- HIV/AIDS Research and Interventions
- Birth, Development, and Health
- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- HIV Research and Treatment
- Folate and B Vitamins Research
- Gestational Diabetes Research and Management
- HIV/AIDS drug development and treatment
- Diabetes Management and Education
- Cardiovascular Function and Risk Factors
- SARS-CoV-2 and COVID-19 Research
- Vitamin D Research Studies
- Mycobacterium research and diagnosis
- Adolescent Sexual and Reproductive Health
- Diabetes Management and Research
- Obesity, Physical Activity, Diet
- Parasites and Host Interactions
- Liver Disease Diagnosis and Treatment
- Food Security and Socioeconomic Dynamics
- Cancer Risks and Factors
- Neuroinflammation and Neurodegeneration Mechanisms
University of Alabama at Birmingham
2023-2024
Kwame Nkrumah University of Science and Technology
1993-2024
Kwame Nkrumah University
2020-2024
Cocoa Research Institute of Ghana
2023
Kumasi Centre for Collaborative Research in Tropical Medicine
2022-2023
University of Science and Technology
2020
University of Cape Coast
2020
Leibniz Institute for Psychology
2020
Ministry of Health
1997
Abstract Background The Coronavirus Infectious Disease 2019 (COVID-19) pandemic has continuously affected human life with several devastating effects. Currently, there are effective vaccines to protect people from COVID‐19 and the World Health Organization (WHO) highlighted strategies influence COVID-19 vaccine uptake in hard-to-reach communities Ghana. However, prior studies on acceptability Ghana online surveys targeting literates those urban areas, leaving residents far-flung communities....
Antenatal care (ANC) is imperative to decreasing adverse pregnancy outcomes and their related maternal mortality. However, in sub-Saharan Africa, increases ANC coverage have not correlated well with improved fetal suggesting the quality of received could be missing link. This study assessed its effect on among women who delivered at Komfo Anokye Teaching Hospital.A cross-sectional was conducted Hospital within period. Women were selected through systematic sampling interviewed using a...
Visceral obesity and insulin resistance contribute to developing cardiometabolic syndrome (MetS). We investigated the predictive abilities of lipid accumulation product (LAP), waist circumference-triglyceride index (WTI), triglyceride-glucose (TyG) for MetS screening among general Ghanaian adults.
Gestational diabetes mellitus (GDM) is a global public health issue that have serious consequences on mother and her child's health. However, limited data available the prevalence of GDM its associated risk factors in Ghana. This study investigated among women attending selected antenatal clinics Kumasi, cross-sectional included 200 pregnant who attended from Three-selected facilities Ashanti Region, Women already diagnosed were identified through their medical records confirmed based...
Cardiometabolic syndrome (MetS) is closely linked to type 2 diabetes mellitus (T2DM) and the leading cause of complications. Anthropometric indices could be used as a cheap approach identify MetS among T2DM patients. We determined prevalence its association with sociodemographic anthropometric patients in tertiary hospital Ashanti region Ghana. A comparative cross-sectional study was conducted 241 outpatients attending Komfo Anokye Teaching Hospital (KATH) Kumasi South for routine check-up....
Preeclampsia is a leading cause of foeto-maternal deaths especially in Sub-Saharan Africa. However, the prevalence and risk factors preeclampsia are scarce Central region Ghana with previous study assessing individual independent factors. This determined algorithm adverse preeclampsia.This multi-centre prospective cross-sectional was conducted from October 2021 to 2022 at Mercy Women's Catholic Hospital Fynba Health Centre region, Ghana. A total 1,259 pregnant women were randomly sampled...
Preterm birth is a global epidemic and leading cause of neonatal mortality in Sub-Saharan Africa. We evaluated the prevalence risk factors preterm among women attending labor ward for delivery at tertiary hospital Ghana. This comparative cross-sectional study was conducted cohort 209 pregnant admitted to Komfo Anokye Teaching Hospital (KATH). Pregnant who delivered between 28 36 completed weeks gestation were classified as whereas those after 37-42 described term. Sociodemographic, clinical,...
Hypertension (HTN) is the leading cause of cardiovascular diseases. Nevertheless, most individuals in developing countries are unaware their blood pressure status. We determined prevalence unrecognized hypertension and its association with lifestyle factors new obesity indices among adult population. This community-based study was conducted 1288 apparently healthy adults aged 18-80 years Ablekuma North Municipality, Ghana. Sociodemographic, characteristics, anthropometric were obtained. The...
Micronutrients, especially calcium (Ca) and magnesium (Mg) are reported to reduce preeclampsia events via several factors such as endothelial cell control, optimal oxidative stress a balanced angiogenic growth mediator. We evaluated the association of micronutrients with biomarkers, mediators in early-onset late-onset preeclampsia.This case-control study recruited 197 (early-onset = 70 127) cases 301 normotensive pregnant women controls from Komfo Anokye Teaching Hospital, Ghana. Samples...
Thyroid disorders and diabetes mellitus coexist are prevalent endocrinopathies among adult population. dysfunction contributes to metabolic imbalances, increase beta-cell apoptosis glucose intolerance. There is paucity of data contradicting findings on how thyroid influence glycaemic control. Therefore, we evaluated control Type 2 (T2DM) patients in Ghana.A comparative cross-sectional study was conducted 192 T2DM from Effia Nkwanta Regional Hospital. Three consecutive monthly fasting plasma...
Vitamin D is a steroid hormone important for the normal functioning of body. It produced through skin exposure to sunlight and from diet. Although Ghana located in tropics where abundant, factors like culture, diet, pigmentation, variation ozone layer, geographical area influence optimization vitamin concentration. imperative evaluate interplay between sunshine exposure, proinflammatory cytokines, mediators metabolism their relationship status three sections among apparent healthy...
WHO recommends HBV-negative babies in high-prevalence (8%) countries receive anti-HBV vaccination. Ghana initiated mass immunization 2002, but concerns remain about vaccine effectiveness and long-term protection. We evaluated immune characteristics factors following hepatitis B vaccination among Ghanaian adolescents who received HBV vaccines.
Abstract Background Late presentation with advanced HIV disease (LP-AHD) remains a significant challenge to Human Immunodeficiency Virus (HIV) care, contributing increased morbidity, mortality, and healthcare costs. Despite global efforts enhance early diagnosis, considerable proportion of individuals infection are unaware being infected therefore present late for care. For the first time in Ghana, this study assessed prevalence LP-AHD associated factors among people diagnosed (PDWH). Method...
Background The association between prolong metformin usage and B12 deficiency has been documented. However, the prevalence estimates of metformin-induced vitamin showed substantial disparity among studies due to varied study definitions deficiency. Metformin blocks calcium dependent absorption B12-Intrinsic Factor complex at terminal ileum. Lack intrinsic factor presence auto-antibodies parietal cells (IFA) could lead subsequently cause peripheral neuropathy. We investigated using more...
Preeclampsia (PE) is associated with endothelial injury and hemostatic abnormalities. However, the diagnostic role of coagulation parameters natural anticoagulants in predicting PE has not been explored Ghana. This study assessed plasma levels these factors as surrogate markers its subtypes. case–control included 90 women (cases) normotensive pregnant (controls). Blood samples were drawn for estimation complete blood count tests. The prothrombin time (PT), activated partial thromboplastin...
The active form of vitamin D has immunomodulatory and anti-inflammatory effect. Vitamin is implicated in pathogenesis rheumatoid arthritis (RA) its deficiency leads to increased inflammation. Moreover, production dependent on concentration calcium, phosphorus, parathyroid hormone (PTH). Cytokines mediates inflammation RA synovium. This study evaluated D, mediators proinflammatory cytokines among patients.
Magnesium sulfate (MgSO
In a comparative experimental cross-sectional study, RNA was extracted from oral swabs and blood samples 25 healthy individuals at the Department of Molecular Medicine, KNUST. by manual AGPC extraction method commercial kits. The quantity (ng/μl) purities (260/280 nm) were measured spectrophotometrically using IMPLEN NanoPhotometer® N60. presence in extracts confirmed 2% agarose gel electrophoresis. Statistical analyses conducted R language.The yield swab modified significantly higher...
Frailty is a condition marked by accumulation of biological deficits and dysfunctions that come with aging it correlated high morbidity mortality in patients cardiovascular diseases, particularly hypertension. Hypertension continues to be leading cause diseases premature death globally. However, there dearth literature sub-Saharan Africa on frailty syndrome among hypertensives medication. This study evaluated its associated factors Ghanaian hypertensives.