A5020502892- Neurotransmitter Receptor Influence on Behavior
- Pain Mechanisms and Treatments
- Neuroscience and Neuropharmacology Research
- Nicotinic Acetylcholine Receptors Study
- Memory and Neural Mechanisms
- Prion Diseases and Protein Misfolding
- Neuroendocrine regulation and behavior
- Neurobiology and Insect Physiology Research
- Neuropeptides and Animal Physiology
- Receptor Mechanisms and Signaling
- Insect and Pesticide Research
- Enzyme function and inhibition
- Stress Responses and Cortisol
- Lipid Membrane Structure and Behavior
- Amphibian and Reptile Biology
- Pharmacological Effects and Assays
- PI3K/AKT/mTOR signaling in cancer
- Pharmacology and Obesity Treatment
- Neural dynamics and brain function
- Cholinesterase and Neurodegenerative Diseases
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Protein Kinase Regulation and GTPase Signaling
- Olfactory and Sensory Function Studies
Universidade de São Paulo
2003-2024
Instituto de Neurociências e Comportamento
2007-2024
Faculdade São Lucas
2017-2019
Faculdades Integradas Aparício Carvalho
2018-2019
Universidade de Ribeirão Preto
2007
Hôpital Saint-Louis
2006
There is a controversy regarding the key role played by opioid peptide neurotransmission in modulation of panic-attack-related responses.Using prey versus rattlesnakes paradigm, present work investigated involvement endogenous peptide-mediated system inferior colliculus panic attack-related responses.Wistar rats were pretreated with intracollicular administration either physiological saline or naloxone at different concentrations and confronted ( Crotalus durissus terrificus). The...
The endogenous opioid peptide system has been implicated in the neural modulation of fear and anxiety organised by dorsal midbrain. Furthermore, previous results indicate a fundamental role played inferior colliculus (IC) mechanisms during expression defensive behaviours, but involvement IC µ1-opioid receptor anxiety- panic attack-related behaviours remains unclear. Using prey-versus-snake confrontation paradigm, we sought to investigate effects blockade on behaviour displayed rats dangerous...
Abstract The dorsal midbrain comprises columns of the periaqueductal grey matter and corpora quadrigemina. These structures are rich in beta-endorphinergic leu-enkephalinergic neurons receive GABAergic inputs from substantia nigra pars reticulata. Although inferior colliculus (IC) is mainly involved acoustic pathways, electrical chemical stimulation central pericentral nuclei IC elicits a vigorous defensive behaviour. immobility escape elicited by activation commonly related to panic-like...
The periaqueductal gray matter (PAG) is an essential structure involved in the elaboration of defensive responses, such as when facing predators and conspecific aggressors. Using a prey vs predator paradigm, we aimed to evaluate PAG activation pattern evoked by unconditioned conditioned fear situations. Adult male guinea pigs were confronted either Boa constrictor wild snake or aversive experimental context. After behavioral test, rodents euthanized brain prepared for immunohistochemistry...
<b><i>Background:</i></b> Gamma-aminobutyric acid (GABA)ergic and opioid systems play a crucial role in the neural modulation of innate fear organised by inferior colliculus (IC). In addition, IC is rich GABAergic fibres neurons, which are also connected to other mesencephalic structures, such as superior substantia nigra. However, contribution distinct receptors (ORs) during elaboration expression panic-like responses unclear. The purpose present work was investigate...