A5068068868- Pain Mechanisms and Treatments
- Neuroscience and Neuropharmacology Research
- Neurotransmitter Receptor Influence on Behavior
- Neuroendocrine regulation and behavior
- Cannabis and Cannabinoid Research
- COVID-19 and Mental Health
- Memory and Neural Mechanisms
- Stress Responses and Cortisol
- Neuropeptides and Animal Physiology
- Sleep and Wakefulness Research
- Botulinum Toxin and Related Neurological Disorders
- Receptor Mechanisms and Signaling
- Neurobiology and Insect Physiology Research
- Pain Management and Placebo Effect
- Neuroscience of respiration and sleep
- Resilience and Mental Health
- Musculoskeletal pain and rehabilitation
- Nicotinic Acetylcholine Receptors Study
- Long-Term Effects of COVID-19
- Psychosomatic Disorders and Their Treatments
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Olfactory and Sensory Function Studies
- Neonatal and fetal brain pathology
- Ion channel regulation and function
- Pediatric Pain Management Techniques
Universidade de São Paulo
2015-2024
Universidade Federal de Alfenas
2018-2024
Instituto de Neurociências e Comportamento
2012-2024
University of Campania "Luigi Vanvitelli"
2019-2024
Fundação Oswaldo Cruz
2024
Universidade de Ribeirão Preto
2009-2023
Universidade Federal de São Carlos
2023
Universitario Francisco de Asís
2020
Fundação Faculdade de Medicina
2004
As lesões cutâneas no pós-operatório, como por pressão perioperatórias (LPP) e infecções do local cirúrgico (ILC), são complicações comuns que impactam a recuperação dos pacientes os custos hospitalares. Esta revisão bibliográfica analisou 189 artigos da base de dados PubMed, selecionando nove estudos relevantes sobre o tema. A prevenção dessas requer uma abordagem multidisciplinar, incluindo avaliação risco precoce, implementação protocolos baseados em evidências educação profissionais...
Abstract It has been shown that GABAA receptor blockade in the dorsomedial and ventromedial hypothalamic nuclei (DMH VMH, respectively) induces elaborated defensive behavioural responses accompanied by antinociception, which utilized as an experimental model of panic attack. Furthermore, prelimbic (PL) division medial prefrontal cortex (MPFC) related to emotional reactions processing nociceptive information. The aim present study was investigate possible involvement PL participation local...
The aim of the present study was to investigate involvement N-methyl-d-aspartate (NMDA) and amino-3-hydroxy-5-methyl-isoxazole-4-proprionate (AMPA)/kainate receptors prelimbic (PL) division medial prefrontal cortex (MPFC) on panic attack-like reactions evoked by γ-aminobutyric acid-A receptor blockade in hypothalamus (MH). Rats were pretreated with NaCl 0.9%, LY235959 (NMDA antagonist), NBQX (AMPA/kainate antagonist) PL at 3 different concentrations. Ten minutes later, MH treated...
Abstract The chronic constriction injury (CCI) of the sciatic nerve is a injury‐based model neuropathic pain (NP). Comorbidities NP such as depression, anxiety, and cognitive deficits are associated with functional reorganization medial prefrontal cortex (mPFC). Here, we have employed an adapted CCI by placing one single loose ligature around in mice for investigating alterations sensory, motor, affective, behavior electrophysiological biochemical properties prelimbic division (PrL) mPFC....
Chronic constriction injury (CCI) is a model of neuropathic pain induced by four loose ligatures around the sciatic nerve. This work aimed to investigate sensory, affective, cognitive, and motor changes an adaptation CCI applying single ligature nerve.Mechanical allodynia was measured from day 1 28 postsurgery von Frey test. The beam walking test (BWT) conducted weekly until days after surgery. Anxiety- depression-like behaviors, cognitive performance were assessed through open field (OF),...
Dysfunction in the hypothalamic GABAergic system has been implicated panic syndrome humans. Furthermore, several studies have hypothalamus elaboration of pain modulation. Panic-prone states are able to be experimentally induced laboratory animals study this phenomenon. The aim present work was investigate involvement medial nuclei organization panic-like behaviour and innate fear-induced oscillations nociceptive thresholds. blockade GABA(A) receptors neuronal substrates ventromedial or...
The present work aimed to investigate the effects of acute sucrose treatment on perception painful stimuli. Specifically, we sought determine involvement endogenous opioid peptide-mediated system as well role μ(1)-opioid receptor in antinociception organisation induced by intake. Nociception was assessed with tail-flick test rats (75, 150 and 250 g) different ages acutely pre-treated 500 μL a solution (25, 50, g/L) or tap water. Young Adult (250 showed after 50 g/L (during 5 min) 20...
COVID-19 pandemic continues to spread exponentially worldwide, especially in America. At the end of August 2020, Brazil is one most affected countries with more than three and a half million cases up 114,250 deaths. This study aims assess fear peri-traumatic stress during pandemics Brazil, enhance infection control methods, appropriate interventions, public health policies. A cross-sectional survey has been conducted from April 12th 18th using Peri-Traumatic Distress Scale (CPDI) Fear...
The periaqueductal gray matter (PAG) consists in a brainstem structure rich 5-hydroxytryptamine (5-HT) inputs related to the modulation of pain. involvement each serotonergic receptor subtypes found PAG columns, such as dorsomedial (dmPAG) and ventrolateral (vlPAG) regarding post-ictal antinociception have not been elucidated. present work investigated participation dmPAG vlPAG columns seizure-induced antinociception. Specifically, we studied neurotransmission these on antinociceptive...