A5066575258- Retinal Diseases and Treatments
- Retinal and Optic Conditions
- Retinal Imaging and Analysis
- Intraocular Surgery and Lenses
- Retinal and Macular Surgery
- Vascular Malformations Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Acne and Rosacea Treatments and Effects
- Ocular Diseases and Behçet’s Syndrome
- Colorectal Cancer Treatments and Studies
- Nasolacrimal Duct Obstruction Treatments
- Herpesvirus Infections and Treatments
- Ocular Surface and Contact Lens
- Hedgehog Signaling Pathway Studies
- Ocular Infections and Treatments
- Dental Anxiety and Anesthesia Techniques
- Orthopedic Infections and Treatments
- Sympathectomy and Hyperhidrosis Treatments
- Osteomyelitis and Bone Disorders Research
- Genetic and rare skin diseases.
- SARS-CoV-2 detection and testing
- Nonmelanoma Skin Cancer Studies
- IgG4-Related and Inflammatory Diseases
- Anesthesia and Pain Management
- HER2/EGFR in Cancer Research
Universitätsmedizin Göttingen
2015-2024
University of Göttingen
2015-2022
Ophthalmology Clinic
2016
This study was performed as a head-to-head comparison of the performance characteristics (1) two SARS-CoV-2-specific rapid antigen assays with real-time PCR gold standard well (2) fully automated high-throughput transcription-mediated amplification (TMA) assay and in latent class analysis-based test without several hundred samples low prevalence "real world" setting. Recorded sensitivity specificity NADAL LumiraDx Hologic Aptima SARS-CoV-2 TMA were 0.1429 (0.0194, 0.5835), 0.7644 (0.7016,...
To develop and compare different analytic approaches for quantifying ischemia in OCT-angiography (OCTA), including vessel-based intercapillary area analysis.En face OCTA (6 × 6) images of the superficial plexus 20 healthy eyes with ischemic retinal diseases were analyzed retrospectively. Included diabetic retinopathy (n = 9), central 5) branch vein occlusion 4), hypertensive 1), occlusive vasculitis sarcoidosis 1). Vessel-based consisted mean gray scale, perfusion density, vessel density....
Die endogene Endophthalmitis entsteht durch die hämatogene Streuung einer bakteriellen oder fungalen Infektion bei schwer vorerkrankten PatientInnen. Eine systemische und intraokulare spezifische Therapie ist erforderlich. Grundlage hierfür der Keimnachweis aus Blutkultur Glaskörperprobe, funktionellen Ergebnisse sind limitiert. Mit dieser Arbeit wollen Autoren praxisnahe Hinweise zur operativen zum von PatientInnen mit endogener geben. Es handelt sich um eine retrospektive Analyse anonymer...
We describe a case of macular hole (MH) closure after intravitreal bevacizumab therapy for an underlying pigment epithelial detachment (PED) due to exudative age-related degeneration (AMD). The 73-year-old Caucasian female presented with reduced visual acuity (20/80) the left eye and metamorphopsia approximately 6 months. Spectral domain optical coherence tomography revealed subfoveal PED AMD associated MH. To treat component pathology, we started therapy, consecutively leading reduction...
The presence of SARS-CoV-2 RNA in anterior chamber fluid and/or the vitreous patients with on ocular surface is unclear. Knowledge about infectious state intraocular structures could influence daily work ophthalmic surgeons.We analyzed samples from a patient who had succumbed to COVID-19 pneumonia for prevalence RNA. We detected viral ocular-surface one swab and excidate conjunctiva. Samples revealed no RNA.SARS-CoV-2 can effectively be inactivated standard disinfection agents. now proven...
To examine the interrater and intrarater reliability of qualitatively quantitatively assessed disorganization retinal inner layers (DRIL) outer (DROL) by multiple raters. Subjectively assessing these surrogate biomarkers can be challenging in daily routine, despite high resolution spectral-domain (SD) OCT scans.Retrospective trial.Three hundred six pooled SD scans 34 patients treated for macular edema caused vein occlusion (RVO) between January 2016 December 2017.SD were 6 raters regarding...
Intraoral local anesthetics are widely used for performing painless dental treatments; however, in some cases, they may cause ocular complications such as meiosis, diplopia, nystagmus, ophthalmoplegia, ptosis, and amaurosis. Mostly, the symptoms disappear after several hours; rarely, have a prolonged character. We describe case of 38-year-old young man who had reduced vision left eye 5 days having received intraoral anesthesia. A diagnosis cilioretinal artery occlusion with optic disc...
Eine 74-jährige Patientin wurde in unserer Klinik für eine Zweitmeinung wegen therapieresistenter rechtsseitiger Kopfschmerzen seit ca. 3 Monaten und wenigen Tagen bestehender höhenversetzter Doppelbilder zugewiesen. Bei V. a. Herpes zoster war bereits 1 Woche mit oralem Aciclovir therapiert worden, Besserung blieb jedoch aus. zusätzliche Schmerzmedikation × tgl. 800 mg Ibuprofen oral half der nur geringfügig.
To correlate functional and morphological parameters with foveal avascular zone's (FAZ) size in diabetic patients mild to moderate stage nonproliferative retinopathy.Monocentric prospective study of a consecutive case series patients. Medical history, best corrected visual acuity (BCVA), high/low contrast (BChcVA/BClcVA), mean sensitivity (MS) defect (MD) central field testing, FAZ fluorescein-angiography (FAG) were recorded. Macular thickness (central point CPT, subfield CST) volume...
585 Background: Members of the EGFR family are established targets for specific therapy approaches in a variety malignancies. Especially HER-2 has been targeted more than decade breast cancer and recently gastric adenocarcinomas gastroesophageal junction. Applying scoring algorithm we here investigated expression rectal using FFPE tumor samples from both large trials German Rectal Cancer Study Group (GRCSG)-(CAO/ARO/AIO-94 -04). Methods: Overall, 839 patients 63 sites were available. All...
Zusammenfassung In der augenärztlichen Praxis sind pathologische Veränderungen Tränendrüse(n) selten anzutreffen. Es überrascht daher nicht, dass sie in Standardwerken häufig nicht im Detail dargestellt sind. Anliegen dieses Artikels ist es, kompakt notwendiges Basiswissen zusammenzustellen und den Bogen zu wichtigen aktuellen Publikationen spannen, um dem Leser nach Lektüre eine umfassende Kenntnis für die tägliche vermitteln.
Eine 74-jährige Patientin wurde unserer Klinik für eine Zweitmeinung wegen therapieresistenter rechtsseitiger Kopfschmerzen seit ca. 3 Monaten und wenigen Tagen bestehender höhenversetzter Doppelbilder zugewiesen. Bei V. a. Herpes zoster war bereits 1 Woche mit oralem Aciclovir therapiert worden, Besserung blieb jedoch aus. zusätzliche Schmerzmedikation 3-mal tgl. 800 mg Ibuprofen oral half der nur geringfügig.
Zusammenfassung In der augenärztlichen Praxis sind pathologische Veränderungen Tränendrüse(n) selten anzutreffen. Es überrascht daher nicht, dass sie in Standardwerken häufig nicht im Detail dargestellt sind. Anliegen dieses Artikels ist es, kompakt notwendiges Basiswissen zusammenzustellen und den Bogen zu wichtigen aktuellen Publikationen spannen, um dem Leser nach Lektüre eine umfassende Kenntnis für die tägliche vermitteln.
SAPHO syndrome (synovitis/acne/pustulosis/hyperostosis, and osteitis) is charaterized by a variable combination of chronic non-specific sterile osteomyelitis, hyperostosis, pustulosis palmoplantaris, acne synovitis. The disease was first described Sonozaki et al. now mostly recognized as distinct entity. However, there still no consensus about the terminology differentiation against similar clinical conditions. Furthermore, pathogenesis unknown, well-tried therapeutic concept has so far been...