A5025789036- Cancer Research and Treatments
- Peroxisome Proliferator-Activated Receptors
- Immune cells in cancer
- Virus-based gene therapy research
- Cancer Cells and Metastasis
- Drug-Induced Hepatotoxicity and Protection
Affiliated Hospital of Jining Medical University
2022
Jining Medical University
2020-2022
Abstract Introduction Acute liver inflammatory reactions contribute to many health problems; thus, it is critical understand the underlying pathogenic mechanisms of acute hepatitis. In this study, an experimental in vivo model concanavalin A (ConA)‐induced hepatitis was used. Materials and Methods C57BL/6 (wild‐type, WT) or inducible nitric oxide synthase‐deficient (iNOS − /− ) mice were injected with PBS 15 mg/kg ConA via tail vein. Detection injury by histological examination apoptosis,...
Gastric cancer is among the most common malignant tumors of digestive tract. Establishing a robust and reliable animal model foundation for studying pathogenesis cancer. The present study established mouse gastric carcinoma by inoculating immunocompetent mice with MKN45 cells using microcarrier. Sixty male C57BL/6 were randomly divided into three groups: 2D group, an empty carrier 3D according to coculture system models hypodermic injection. Time develop tumor, rate tumor formation,...