A5090127740- Bacteriophages and microbial interactions
- Bacterial Genetics and Biotechnology
- RNA and protein synthesis mechanisms
- Genomics and Phylogenetic Studies
- Microbial Community Ecology and Physiology
- bioluminescence and chemiluminescence research
- Advanced biosensing and bioanalysis techniques
- Microbial infections and disease research
- Arsenic contamination and mitigation
- Chromium effects and bioremediation
- Trace Elements in Health
- Biosensors and Analytical Detection
- Chromosomal and Genetic Variations
- Water Treatment and Disinfection
- Bacterial biofilms and quorum sensing
- Polar Research and Ecology
- DNA Repair Mechanisms
- Plasma Applications and Diagnostics
- CRISPR and Genetic Engineering
- Marine Biology and Environmental Chemistry
- RNA modifications and cancer
- Plasma Diagnostics and Applications
- DNA and Nucleic Acid Chemistry
- Legionella and Acanthamoeba research
- Plant-Microbe Interactions and Immunity
Institut de Biologie Intégrative de la Cellule
2015-2023
CEA Paris-Saclay
2018-2023
Centre National de la Recherche Scientifique
2009-2023
Université Paris-Saclay
2017-2023
Commissariat à l'Énergie Atomique et aux Énergies Alternatives
2018-2023
Université Paris-Sud
2006-2019
Expression Génétique Microbienne
2008-2012
McGill University
1992-2005
Mount Sinai Hospital
2005
Migration Institute of Australia
1990-1993
Bacteriophages are the most abundant life forms in biosphere. They play important roles bacterial ecology, evolution, adaptation to new environments, and pathogenesis of human infections. Here, we report complete genomic sequences, predicted proteins 27 bacteriophages Gram-positive bacterium Staphylococcus aureus . Comparative nucleotide protein sequence analysis indicates that these phages a remarkable source untapped genetic diversity, encoding 2,170 protein-encoding ORFs, which 1,402...
Arsenic is a known toxic metalloid, whose trivalent and pentavalent ions can inhibit many biochemical processes. Operons which encode arsenic resistance have been found in multicopy plasmids from both gram-positive gram-negative bacteria. The mechanism encoded single operon typically consists of an arsenite ion-inducible repressor that regulates expression arsenate reductase inner membrane-associated export system. Using lacZ transcriptional gene fusion library, we identified Escherichia...
A genomic analysis of 18 P. aeruginosa phages, including nine newly sequenced DNA genomes, indicates a tremendous reservoir proteome diversity, with 55% open reading frames (ORFs) being novel. Comparative sequence and ORF map organization revealed that most the phages analyzed displayed little relationship to each other.
SUMMARY: Operons encoding homologous arsenic-resistance determinants (ars) have been discovered in bacterial plasmids from Gram-positive and Gram-negative, organisms, as well the Escherichia coli chromosome. However, evidence for this determinant medically environmentally important species Pseudomonas aeruginosa is conflicting. Here identification of a P. chromosomal ars operon homologue via cloning complementation an E. mutant reported. The contains three potential ORFs proteins with...
ABSTRACT Degradation of the quorum-sensing (QS) signals known as N -acylhomoserine lactones (AHL) by soil bacteria may be useful a beneficial trait for protecting crops, such potato plants, against worldwide pathogen Pectobacterium . In this work, analytical chemistry and microbial molecular approaches were combined to explore compare biostimulation native introduced AHL-degrading Rhodococcus erythropolis populations in rhizosphere plants cultivated farm greenhouses under hydroponic...
Biofilms represent the most common microbial lifestyle, allowing survival of populations exposed to harsh environmental conditions. Here, we show that biofilm development a bacterial species belonging Thiomonas genus, frequently found in arsenic polluted sites and playing key role natural remediation, is markedly modified when subinhibitory doses this toxic element. Indeed, arsenite [As(III)] exposure led considerable impact on maturation by strongly increasing extracellular matrix synthesis...
Enterococcus faecalis is an opportunistic pathogen that has emerged as a major cause of nosocomial infections worldwide. Many clinical strains are indeed resistant to last resort antibiotics and there consequently reawakening interest in exploiting virulent phages combat them. However, little still known about phage receptors resistance mechanisms enterococci. We made use prophageless derivative the well-known strain E. V583 isolate belonging Picovirinae subfamily P68 genus we named Idefix....
FRET and rolling circle amplification outperform RT-qPCR for microRNA diagnostics in clinical samples.
Ramlibacter tataouinensis TTB310T (strain TTB310), a betaproteobacterium isolated from semi-arid region of South Tunisia (Tataouine), is characterized by the presence both spherical and rod-shaped cells in pure culture. Cell division strain TTB310 occurs binary fission "cyst-like" ("cyst-cyst" division). The formed at periphery colony (consisting mainly cysts) are highly motile colonize new environment, where they form reversion to cyst-like cells. This unique cell cycle TTB310, with...
The aim of this study was to compare the composition two deep-sea viral communities obtained from Romanche Fracture Zone in Atlantic Ocean (collected at 5200 m depth) and southwest Mediterranean Sea (from 2400 using a pyro-sequencing approach. results are based on 18.7% 6.9% sequences Sea, respectively, with hits genomes non-redundant RefSeq database. identifiable richness relative abundance both viromes were dominated by archaeal bacterial viruses accounting for 92.3% 83.6% Sea. Despite...