A5047003289- Renal Diseases and Glomerulopathies
- Chronic Kidney Disease and Diabetes
- Ferroptosis and cancer prognosis
- Erythropoietin and Anemia Treatment
- Vasculitis and related conditions
- Chemical Reactions and Isotopes
- Advanced NMR Techniques and Applications
- Acute Kidney Injury Research
- Ovarian function and disorders
- Glaucoma and retinal disorders
- Radiomics and Machine Learning in Medical Imaging
- Cancer Research and Treatment
- Neurological disorders and treatments
- Dialysis and Renal Disease Management
- Sepsis Diagnosis and Treatment
- Calcium signaling and nucleotide metabolism
- Diabetic Foot Ulcer Assessment and Management
- Metabolism and Genetic Disorders
- Epilepsy research and treatment
- Anesthesia and Neurotoxicity Research
- Growth Hormone and Insulin-like Growth Factors
- Retinal and Macular Surgery
- Machine Learning in Healthcare
- Pregnancy and Medication Impact
- Intraocular Surgery and Lenses
Hunan Normal University
2025
Hunan Provincial People's Hospital
2025
Peking University
2014-2024
First Affiliated Hospital of Guangzhou University of Chinese Medicine
2024
China-Japan Friendship Hospital
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Xiangya Hospital Central South University
2023
Central South University
2023
Peking University First Hospital
2014-2022
The First People's Hospital of Zhaoqing
2019
<title>Abstract</title> Background Current sepsis biomarkers have limitations, but mass spectrometry-based proteomics can identify patients at high risk of mortality or organ dysfunction, the molecular mechanisms pediatric sepsis, and reveal personalized therapeutic strategies, with high-risk cohorts benefiting from early accurate identification through clinical biomarkers. Methods The young mice were randomly divided into sham groups(D0), then plasma was dissected D0, day 1(D1), day3(D3)...
The current study was designed to observe the ultrastructural changes of podocyte foot processes during remission phase and its relationship with amount proteinuria in patients minimal change disease (MCD).Electron micrographs glomerular capillaries were taken from 33 adult cases MCD, including 12 nephrotic syndrome, 15 partial six complete remission. classified into three grades by ratio height basal width: 0.5-1, 1-2 ≥2. process width (FPW) number different per 10 μm basement membrane...
To construct a diabetes foot prediction model for adult patients with type 2 based on retrospective cohort study using data from regional health platform.
To develop a prediction model for the risk of diabetic retinopathy (DR) in patients with newly diagnosed type 2 diabetes mellitus (T2DM).
To construct a risk prediction model for diabetes kidney disease (DKD).
Objective: To investigate the relationship between intraoperative electroencephalogram burst suppression (BS) and emergence delirium (ED) in elderly patients undergoing elective laparoscopic surgery under total intravenous anesthesia (TIVA). Methods: From October 2017 to September 2019, a of 358 who underwent TIVA at Xiangya Hospital, Central South University, were included. Patients divided into two groups based on confusion assessment method for intensive care unit (CAM-ICU) conducted...
Objective: To summarize the clinical characteristics and features of electroencephalograph (EEG) children with DEPDC5 gene variants related epilepsy. Methods: The data, variation, EEG head magnetic resonance image (MRI) 20 epileptic admitted to Department Pediatrics, Peking University First Hospital from May 2017 November 2020 were retrospectively analyzed. Results: Twenty patients heterozygous enrolled, 8 nonsense variants, 6 missense 3 frame-shift 2 splicing 1 was large fragment deletion....
Three patients diagnosed with focal cortical dysplasia (FCD) in the First Hospital of Peking University from September to November 2020 were recruited study. Based on stereotactic electroencephalogram (SEEG) or electrocorticogram (ECoG) analysis localize seizure onset zone (SOZ), RNA sequencing (RNA-seq) was performed for SOZ and para-SOZ tissue obtained surgery. The differentially expressed genes between samples analyzed by performing Go (Gene ontology) Kyoto Encyclopedia Genes Genomes...
左旋咪唑是20世纪60年代发现的一种抗蠕虫药；临床应用中发现其具有免疫调节作用后逐渐应用于多种免疫相关性疾病的免疫调节。左旋咪唑治疗儿童肾病综合征的研究在不同的国家和地区都有所开展；但其作用机制、最佳给药方案等仍需进一步探索。为了全面地了解左旋咪唑在儿童肾病综合征中的应用和作用，本文对左旋咪唑治疗儿童肾病综合征的作用机制、不同给药频率的疗效研究、药代动力学、不良反应等进行综述。.
Objective: To assess the correlation of glomerular C1q or IgA deposition with clinical and pathological features primary membranous nephropathy (PMN) in children. Methods: The manifestations including (phospholipase A2 receptor, PLA2R) IgG subclasses staining renal biopsies, serum anti-PLA2R antibody therapeutic response 33 children diagnosed PMN Peking University First Hospital from December 2012 to 2020 were retrospectively summarized analyzed. According results PLA2R test findings...
Objective: To assess the reliability of estimated urine protein to predict 24 h excretion in children with glomerular diseases. Methods: Four hundred and forty-three diseases, who were admitted pediatric department Peking University First Hospital from January 2001 December 2021, enrolled cross-sectional study. The creatinine which calculated by 6 previously described equations, measured creatinine, protein-to-creatinine ratio(UPCR), (24 hUP) urinary sediment analysis microscopy collected,...