A5046156146- Schizophrenia research and treatment
- Mental Health and Psychiatry
- Diet and metabolism studies
- Bipolar Disorder and Treatment
- Health, psychology, and well-being
- Health disparities and outcomes
- Physical Activity and Health
- Cardiac Health and Mental Health
- Mental Health Treatment and Access
- Cardiac electrophysiology and arrhythmias
- Psychosomatic Disorders and Their Treatments
- Smoking Behavior and Cessation
- Palliative Care and End-of-Life Issues
- Music Therapy and Health
- Grief, Bereavement, and Mental Health
- Health Policy Implementation Science
- Healthcare Decision-Making and Restraints
- Pain Management and Placebo Effect
- Chronic Disease Management Strategies
- Diabetes Management and Research
- Cancer Treatment and Pharmacology
- Health Systems, Economic Evaluations, Quality of Life
- Eating Disorders and Behaviors
- Cancer therapeutics and mechanisms
- School Health and Nursing Education
Region of Southern Denmark
2017-2025
Mental Health Services
2018-2025
University of Southern Denmark
2017-2025
Psykiatrien i Region Syddanmark
2013-2024
Aarhus University Hospital
2005-2017
Regional Hospital Randers
2015-2017
Aarhus University
2002-2015
Central Denmark Region
2015
Aalborg University Hospital
2011-2013
Copenhagen University Hospital
2006
The arterial content of hyaluronan (HA) undergoes diffuse changes as part the diabetic macroangiopathy. Because HA influences phenotype vascular cells in vitro such proliferation, migration, and secretion, it is tempting to speculate that diabetes-induced hastened cardiovascular disease may be linked increased amount HA. To explore pathophysiological role altered wall vivo, we created transgenic (Tg) mice with overexpression smooth muscle (SMCs) large small vessels, targeted by alpha...
Objective To explore physical health problems and their causes in patients with severe mental illness, as well possibilities for prevention treatment from the patients' staff's perspectives. Method We conducted six focus groups staff separately, three out-patient clinics treating schizophrenia or substance-use disorder comorbid to another psychiatric disorder. Focus were audio-recorded, transcribed verbatim analysed using a template approach. Results Paramount are weight issues,...
Background Patients with severe mental illness experience serious inequity when facing cancer treatment. They are less likely to be referred for treatment following recommended guidelines and have poorer survival than patients without illness. Relevant specialties such as psychiatry general practice rarely involved, the patient perspective is represented in research field. The present study investigated how barriers facilitators of patient-centred care. Methods In this qualitative case...
While psychiatric treatment mostly focuses on mental health, comorbid somatic conditions are frequent and often undertreated. This study aimed to bridge the gap by assessing feasibility of medical consultations for inpatients identify lifestyle-related conditions, as well abnormal paraclinical findings. Secondly, we treatments diagnoses associated with metabolic outcomes. Patients admitted Department Psychiatry Vejle, Denmark, between October 2022 December 2023 were invited participate in a...
1. Parsons A, Daley Begh R, Aveyard P. Influence of smoking cessation after diagnosis early stage lung cancer on prognosis: systematic review observational studies with meta-analysis. BMJ. 2010;340:b5569. doi:10.1136/bmj.b5569 CrossRef Google Scholar
Patients with psychiatric illness have increased somatic morbidity and mortality. Knowledge of how to integrate the prevention care into treatment patients is required. The aims this study were investigate whether an intervention programme improve physical health effective.An extension European Network for Promoting Health Residents in Psychiatric Social Care Institutions (HELPS) project further developed as a 12-month controlled cluster-randomized Danish centre. Waist circumference was...
People with mental disorders have a higher prevalence of physical illnesses and reduced life expectancy as compared the general population. However, there is lack knowledge across Europe concerning interventions that aim at reducing somatic morbidity excess mortality by promoting behaviour-based and/or environment-based interventions. HELPS an interdisciplinary European network aims (i) gathering relevant on illness in people illness, (ii) identifying health promotion initiatives countries...
Patients with schizophrenia experience low quality of life (QOL).To examine QOL in these patients and the relation between illness duration, adjusted daily doses (ADDs) antipsychotics, body mass index (BMI), waist circumference smoking.In this naturalistic, cross-sectional study, 82 were interviewed about smoking habits. completed a questionnaire (World Health Organization Quality Life-Bref) consisting physical, psychological, social environmental domains had height, weight measured. The...
Abstract Background Hospital visits constitute a ‘window of opportunity’ for initiating smoking cessation attempts, and healthcare providers (HCPs) play an important role in supporting patients to stop smoking. Yet, the current practices hospital setting are largely unexplored. The aim this study was explore support among hospital-based HCPs. Methods HCPs working large secondary care sector completed online, cross-sectional survey, including sociodemographic work-related factors as well 21...
Patients with schizophrenia experience low quality of life (QoL) and poor physical health, which is explained, in part, by unhealthy lifestyle, tobacco smoking, diet sedentary behavior.To measure QoL health patients to quantify associations between health.This was a naturalistic longitudinal 30-month follow-up study including individual guidance, group sessions treatment as usual.We included 190 patients. among newly diagnosed Higher body mass index significantly associated lower QoL. Newly...
Objective Antipsychotics are associated with a polymorphic ventricular tachycardia, torsades de pointes, which, in the worst case, can lead to sudden cardiac death. The QT interval corrected for heart rate (QTc) is used as clinical proxy pointes. QTc be prolonged by antipsychotic monotherapy, but it unknown if further polypharmaceutical treatment. Therefore, this study investigated associations between and monotherapy treatment schizophrenia, measured frequency of prolongation among...
Patients with co-existence of psychiatric disorders and substance use have an increased risk premature death. This is attributable to a higher prevalence physical comorbidities lifestyle related use. Furthermore, they experience low quality-of-life (QoL). Studies addressing interventions for these patients are warranted.To investigate the health QoL in use, analyse changes their (a) health, (b) (c) after 24-month health-promotion programme. Further aims were associations between number...
Background: Patients with severe mental illnesses have an increased physical morbidity and premature mortality on account of somatic diseases. illness are nursed cared for by the staff, who may acts as role models patients. Aims: The study tested efficacy intervention programme improving health in staff working long-term psychiatric treatment facilities. Furthermore, paper measured association between staff's changes patients' health. Methods: was a cluster randomized controlled 12-month...
Our purpose was to elucidate the hypothesis that paracrine-produced transforming growth factor (TGF)-beta1 regulates accumulation of extracellular matrix (ECM) in renal glomeruli, a hallmark diabetic nephropathy. To produce TGF-beta1 from juxtaglomerular apparatus mouse kidneys, we cloned Ren-1c promoter fragment (-4.100 +6 base pairs) upstream porcine (pTGF-beta1) cDNA, mutated ensure secretion biologically active TGF-beta beta1. The resulting transgenic mice had significantly more their...
People with mental disorders have higher mortality from lifestyle diseases than the general population. Forensic health patients (FMHPs) are often hospitalised for longer periods of time non-FMHPs. Thus, hospitalisation may a greater effect on risk in FMHPs.Investigate associations between proportional (PHT) and change body weight or other cardiometabolic factors among FMHPs.Retrospective cohort study including all FMHPs schizophrenia bipolar disorder, prescribed antipsychotics, treated 01...