- Diet and metabolism studies
- Liver Disease Diagnosis and Treatment
- Traditional Chinese Medicine Analysis
- Advanced Memory and Neural Computing
- Genetic factors in colorectal cancer
- Phytochemicals and Antioxidant Activities
- Electrocatalysts for Energy Conversion
- Endoplasmic Reticulum Stress and Disease
- Immune cells in cancer
- Lipid metabolism and disorders
- Medicinal Plant Research
- Nanomaterials for catalytic reactions
- Nutrition, Genetics, and Disease
- Digestive system and related health
- Ammonia Synthesis and Nitrogen Reduction
- Natural Antidiabetic Agents Studies
- Advanced battery technologies research
- Energetic Materials and Combustion
- Atherosclerosis and Cardiovascular Diseases
- Adipose Tissue and Metabolism
- Educational Research and Science Teaching
- Diet, Metabolism, and Disease
- Gut microbiota and health
- Andrographolide Research and Applications
Shanxi University
2023-2024
North University of China
2023
Shanxi University of Traditional Chinese Medicine
2022
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic hepatic manifestation of metabolic dysfunction for which effective interventions are lacking. The burden NAFLD increasing at an alarming rate. frequently associated with morbidities such as dyslipidemia, type 2 diabetes mellitus and obesity, etc. current study explored potential role bound polyphenols from foxtail millet (BPIS) in treating mice induced by a high-fat diet (HFD). results indicated critical BPIS effectively...
Abstract GLP‐1 is a vital candidate for stimulating insulin secretion in glucose‐dependent manner, reducing body weight and eliminating nonalcoholic fatty liver disease with few side effects. Therefore, elevating antagonizing the enzymatic cleavage by DPP4 are main direction of GLP‐1‐based drug development. The present study implies that ferulic acid (FA) treatment increased serum level diet‐induced obesity mice. binding FA to effectively prevented DPP4, which led effective elimination...
Chemoresistance is one of the difficulties in treatment colorectal cancer (CRC), and enhanced stemness tumor cells underlying contributing factor. Leucine-rich repeat-containing G-protein-coupled receptor 5 (LGR5) a classical marker CRC stem can be an important potential target for chemotherapy. Quinoa, protein-rich plant, offers as source high-quality active peptides. Novelly, study obtained quinoa protein hydrolysate (QPH) from whole grains by simulated digestion. In vivo experiments...
To solve the problems of traditional production process ultrafine nitroguanidine (NQ), such as a long and easy pollution caused by recrystallization, NQ (2–6 μm) was prepared one-step crystallization in an impinging stream-rotating packed bed (IS-RPB). The influence operation parameters on size crystal discussed through various particle characterization methods. Results show that IS-RPB 2.0–3.0 μm, which smaller than market products conformed to military standard. Simultaneously, morphology...
Abstract Chemoresistance is a major cause of breast cancer (BC) recurrence and metastasis, chemotherapy resistance comes from tumor stemness. Our previous study showed that quinoa bran terpenoids (QBT) exhibited significant antitumor activity. In this study, we found QBT increased the sensitivity drug‐resistant BC cells to chemotherapeutic drugs adriamycin (ADR) taxol (TAX). A novel lncRNA 667012 was identified along with treatment. Moreover, overexpression promoted drug resistance,...
Quinoa is a healthy food that beneficial for obese people. It rich in flavonoids, and has the functions of reducing blood glucose lipids, losing weight. However, its mechanism regulating metabolism main active ingredients have not been deeply explored. So we investigate effective components biological quinoa flavone relieving obesity-induced damage intestinal L cells. We analyzed effect metabolic diseases mainly caused by inflammatory reactions on endocrine Then discovered can repair...
Ethnopharmacological relevance: Salvianolic acid A (SAA) is the main active component of classic anti-atherosclerotic drug Salvia miltiorrhiza Bunge. Inflammation-induced infiltration monocytes/macrophages into vascular wall initiating step in atherogenesis, and targeted blocking this may provide a promising avenue for precise treatment atherosclerosis. However, effect salvianolic on macrophages still unknown.Aim studyTo evaluate SAA macrophage underlying mechanism against...