A5048631551- Gut microbiota and health
- Diet and metabolism studies
- Gastrointestinal motility and disorders
- Biosensors and Analytical Detection
- Advanced Sensor and Energy Harvesting Materials
- RNA Interference and Gene Delivery
- Characterization and Applications of Magnetic Nanoparticles
- Pelvic floor disorders treatments
- Advanced biosensing and bioanalysis techniques
- Virus-based gene therapy research
- Liver Disease Diagnosis and Treatment
- Liver physiology and pathology
- Gastric Cancer Management and Outcomes
- Immunotherapy and Immune Responses
- Chronic Myeloid Leukemia Treatments
- Microfluidic and Bio-sensing Technologies
- PI3K/AKT/mTOR signaling in cancer
- Micro and Nano Robotics
- Adipose Tissue and Metabolism
- Anorectal Disease Treatments and Outcomes
- Gas Sensing Nanomaterials and Sensors
- Drug Transport and Resistance Mechanisms
- Traditional Chinese Medicine Analysis
- Food composition and properties
- Magnetic Properties and Applications
Shanxi Academy of Medical Sciences
2016-2025
Shanxi Medical University
2008-2025
Shanxi University
2024
Huazhong University of Science and Technology
2021
Shanxi Dayi Hospital
2016-2019
First Hospital of Shanxi Medical University
2008-2010
Depression and anxiety are common comorbid diseases of constipation. Fecal microbiota transplantation (FMT) significantly relieves gastrointestinal-related symptoms, but its impact on psychiatric symptoms remains uncharted.
Neratinib has emerged as significant theraputic option for breast cancer treatment. However, despite its approval, numerous adverse drug events (ADEs) associated to it remain unrecognized and unreported. This study aims mine analyze the signals of ADEs related neratinib from US Food Drug Administration Adverse Event Reporting System (FAERS) database, providing insights safe rational clinical use drug.
Background Chronic constipation is one of the most prevalent functional gastrointestinal disorders, yet its etiology multifactorial, and pathophysiological mechanism still unclear. Previous studies have shown that gut microbiota constipated patients differs from healthy controls; however, many discrepancies exist in findings, no clear link has been confirmed between chronic changes microbiota. Growing evidence indicates age, gender, hormone levels can affect composition The aim this study to...
Evidence is limited regarding the relationship between sleep factors (self-reported disorder diagnosis, subjective difficulties, and duration), patterns, risk of type 2 diabetes mellitus (T2D). Thus, this study aims to investigate factors, T2D using data from National Health Nutrition Examination Survey (NHANES). A total 14,652 individuals aged ≥18 years NHANES (2005-2014) were enrolled with complete on T2D, covariates. Information self-reported duration was collected during in-home visits...
Human exposure to heavy metals occurs through multiple pathways in daily life. However, the effects of mixed metal on accelerated aging elderly U.S. population remains unclear. This study aims investigate association between concentrations blood and urine onset aging. A total 2530 individuals were included analysis 716 this study. GrimAge acceleration (AgeAccelGrim) was calculated as residuals from regressing DNA methylation chronological age. Weighted multivariable logistic regression...
A variation of familial adenomatous polyposis (FAP), known as Gardner's syndrome (GS), can manifest extraintestinal tumors, such desmoid tumors (DTs). key part in the diagnosing process is played by clinician. Because DT frequently occurs before intestinal develops, doctors identify underlying illness early looking for DT's telltale signs. Nevertheless, this instance, patient's failure to recognize promptly following excision tumor abdomen wall caused a delay diagnosis and impacted disease's course.
A factor closely associated with renal disease status in clinical diagnosis is abnormal human serum albumin (HSA) concentration levels body fluids urine, serum, etc. The surface stress biosensor was developed as a new type of to detect protein molecule and has wide range applications. However, further sensitivity improvement required achieve higher detection performance. Herein, MXene/PDMS/Fe3O4/PDMS the multilayer heterogeneous membrane (MHBios) based on coupling magnetic field, electric...
Recently, mechanical biosensors have attracted more attention on single molecule detection due to its high accuracy, low cost, and convenience. However, the sensitivity of restricted their clinical application. Herein, a biosensor based membrane-mediated magneto-stress-electric coupled sensitization (MSEC-MMB) was developed enhance performance. Through introducing Fe3O4 nanoparticles (MNPs) traditional stress-electric applying magnetic field, biosensing system constructed. The MSEC-MMB...
The development of 3D print technology provided an opportunity to achieve fast and accurate fabrication wearable sensor arrays. In this paper, high-sensitivity flexible stretchable silver-coated carbon nanotube (Ag@CNT) strain arrays are fabricated using printing composite nanomaterial synthesis. Ag@CNTs with uniform compact particles were synthesized different sizes nanotubes (CNTs) a reduction method. Strain accurately efficiently the aid printed molds. Sensors then compared...
Chronic constipation is a common gastrointestinal disorder that occurs in the elderly and women. Psyllium husk widely used to treat this condition. Recent studies have shown psyllium can improve clinical symptoms of by regulating gut microbiota, but its effects potential mechanisms constipated women reproductive age not been previously investigated. We compared fecal microbiota after treatment with placebo (n = 29) 25) using 16S ribosomal ribonucleic acid (rRNA) gene sequencing analysis....
The satisfactory prognostic indicator of gastric cancer (GC) patients after surgery is still lacking. Perioperative plasma extracellular vesicular programmed cell death ligand-1 (ePD-L1) has been demonstrated as a potential prognosis biomarker in many types cancers. value postoperative ePD-L1 not characterized.We evaluated the preoperative, and change ePD-L1, well soluble PD-L1, short-term survival GC surgery. Kaplan-Meier model Cox proportional hazards models for both univariate...
Background As a three-dimensional network involving glycosaminoglycans (GAGs), proteoglycans (PGs) and other glycoproteins, the role of extracellular matrix (ECM) in tumorigenesis is well revealed. Abnormal glycosylation liver cancer correlated with chemoresistance. However, galactosyltransferase HCC (hepatocellular carcinoma) largely unknown. Methods Here, oncogenic functions B4GALT7 (beta-1,4-galactosyltransferase 7) were identified by panel vitro experiments, including MTT...
Background: The aim of our study was to develop a nomogram model predict overall survival (OS) and cancer-specific (CSS) in patients with gastric signet ring cell carcinoma (GSRC). Methods: GSRC from 2004 2015 were collected the Surveillance, Epidemiology, End Results (SEER) database randomly assigned training validation sets. Multivariate Cox regression analyses screened for OS CSS independent risk factors nomograms constructed. Results: A total 7,149 eligible identified, including 4,766...
Abstract Flexible sensor is one of the prevalent directions in field, and sensing material structure are main aspects that affect performance sensor. This paper studies a flexible pressure based on Graphene/MXene‐PDMS @ sponge. Using porous skeleton sponge high conductivity synergy Graphene MXene to prepare set sensitivity (0.053kPa −1 ), stability (2000 cycles loading), variability (0–35 kPa detection limit), all‐in‐one In rectal model experiment, array can effectively detect static...
Abstract The membrane based on receptor functionalization provides a new paradigm for the development of mechanical biosensors. However, improvement sensitivity and test accuracy is still challenge biosensors in practical application. Herein, surface stress biosensor (MBioS) double‐side‐gold nanoparticale (AuNP)‐coated grid‐type polydimethylsiloxane (PDMS) (D‐G‐MBioS) 3D printing human serum albumin (HSA) detection developed. amplified by grid coupling sandwich immune structure to improve...
Back Cover: In article number 2100251, Qiang Zhang and co-workers propose a flexible pressure sensor based on graphene/[email protected] The exhibits high sensitivity (0.053 kPa−1), stability (2000 cycles loading) variability (0 – 35 kPa detection limit). Furthermore, the array can effectively detect static pressure, systolic corresponding abnormal in rectal model experiment, which show good prospect detecting pressure.