A5051755171- Celiac Disease Research and Management
- Microscopic Colitis
- Digestive system and related health
- Emergency and Acute Care Studies
- Eosinophilic Esophagitis
- Gastrointestinal motility and disorders
- Helicobacter pylori-related gastroenterology studies
- Microbial Metabolites in Food Biotechnology
- Heart Failure Treatment and Management
- Child Nutrition and Feeding Issues
- Patient Safety and Medication Errors
- Geriatric Care and Nursing Homes
- Eating Disorders and Behaviors
- Traumatic Brain Injury and Neurovascular Disturbances
- Whipple's Disease and Interleukins
- Hospital Admissions and Outcomes
- Neurosurgical Procedures and Complications
- Patient-Provider Communication in Healthcare
- Radiation Dose and Imaging
- Appendicitis Diagnosis and Management
- Galectins and Cancer Biology
- Healthcare Decision-Making and Restraints
- Therapeutic Uses of Natural Elements
- Pharmacovigilance and Adverse Drug Reactions
- Potassium and Related Disorders
Eastern Health
2013-2024
Monash University
2013-2024
Box Hill Hospital
2006-2017
Australian Regenerative Medicine Institute
2014
OBJECTIVES: Despite increased prescription of a gluten-free diet for gastrointestinal symptoms in individuals who do not have celiac disease, there is minimal evidence that suggests gluten trigger. The aims this study were to determine whether ingestion can induce non-celiac and examine the mechanism. METHODS: A double-blind, randomized, placebo-controlled rechallenge trial was undertaken patients with irritable bowel syndrome whom disease excluded symptomatically controlled on diet....
Background : Nonceliac gluten sensitivity (NCGS), occurring in patients without celiac disease yet whose gastrointestinal symptoms improve on a gluten‐free diet (GFD), is largely self‐reported diagnosis and would appear to be very common. The aims of this study were characterize who believe they have NCGS. Materials Methods Advertising was directed toward adults believed had NCGS willing participate clinical trial. Respondents asked complete questionnaire about symptoms, diet, investigation....
Summary Background Mild impairments of cognition or ‘Brain fog’ are often reported by patients with coeliac disease but the nature these has not been systematically investigated. Aim This longitudinal pilot study investigated relationships between cognitive function and mucosal healing in people newly diagnosed commencing a gluten‐free diet. Methods Eleven (8 females, 3 males), mean age 30 (range 22–39) years, were tested battery tests at weeks 0, 12 52. Information processing efficacy,...
Key aims of treatment coeliac disease are to heal the intestinal mucosa and correct nutritional abnormalities.We aim determine prospectively degree success time course achieving those goals with a gluten-free diet.Ninety-nine patients were enrolled at diagnosis taught diet. The first 52 reassessed 1 year 46 5 years, 25 being assessed three points regarding dietary compliance (dietitian-assessed), serology, bone mineral density body composition analysis by dual energy X-ray absorptiometry,...
Objectives To understand from a patient and carer perspective: (1) what features of the discharge process could be improved to avoid early unplanned hospital readmission (within 72 hours acute care discharge) (2) elements planning have enhanced experience. Design A qualitative descriptive design was used. Study data were collected using semi-structured interviews that transcribed verbatim analysed inductive thematic analysis. Data related participant characteristic by medical record audit...
Summary Background While potential risks of diagnostic medical radiation are acknowledged, actual exposure patients in routine clinical practice is poorly documented. Aim To quantify such to vulnerable abdominal organs with inflammatory bowel disease who already at risk intestinal cancer. Methods All incidences were documented a consecutive series 100 (62 Crohn’s disease, 37 ulcerative colitis, 1 indeterminate colitis) attending hospital‐based clinic. Total effective dose (mSv) was...
The past decade has seen human leukocyte antigen (HLA) typing emerge as a remarkably popular test for the diagnostic work-up of coeliac disease with high patient acceptance. Although limited in its positive predictive value disease, strong association specific HLA genes imparts exceptional negative to typing, enabling result exclude confidently. In response mounting evidence that clinical use and interpretation often deviates from best practice, this article outlines an evidence-based...
Scope Since epithelial barrier dysfunction has been associated with gluten and fermentable oligosaccharide, disaccharide, monosaccharide, polyols (FODMAPs), the effect of alterations in FODMAP a intake on function patients irritable bowel syndrome (IBS) who self‐reported sensitivity. Methods results Circulating concentrations markers injury (syndecan‐1 intestinal fatty acid‐binding protein) bacterial translocation (lipopolysaccharide‐binding protein soluble CD14) are measured while consuming...
Abstract Background Perception of diarrhea and constipation differs greatly. This study aimed to correlate subjective objective assessment fecal characteristics in irritable bowel syndrome ( IBS ) patients. Methods Data from two interventional dietary trials with varying FODMAP (Fermentable Oligosaccharides, Disaccharides, Monosaccharides And Polyols) or gluten content were interrogated. Subjects rated their dissatisfaction stool consistency daily using a visual analog scale during the...
Data on the optimal use of conventional therapies in Crohn's disease are lacking guidelines. An educational programme was established to explore questions raised clinical practice and provide practical answers.Telephone interviews with 96 gastroenterologists a web survey 1370 identified 26 key questions. Ten were taken forward next stage based opinion an International Steering Committee. Draft answers prepared from available evidence following literature search. The draft debated national...
Active inflammatory bowel disease, anaemia, iron deficiency and depression, alone or in combination, are known contributing factors of fatigue disease. However, some patients, cannot be attributed to causes. Thiopurines not a recognized cause.To describe the clinical scenario series patients where thiopurines were likely cause fatigue.The 5 was examined with specific reference temporal association thiopurine therapy fatigue, effect its withdrawal rechallenge, drug specificity.The onset...
Abstract Background Patients with anorexia nervosa (AN) are vulnerable to physiological decompensation and often require inpatient management by an eating disorders unit. Aims admitted Australian tertiary medical centre for stabilisation of AN were assessed as part quality assurance. Analysis included: (i) complications during acute stabilisation; (ii) predictors refeeding syndrome; (iii) governing length stay (LOS); (iv) outcomes pre‐ post‐implementation multidisciplinary treatment...
Abstract An audit of the in‐hospital safety and tolerability 401 infusions iron polymaltose in 386 patients has shown no cases anaphylaxis or other cardiorespiratory compromise. The infusion was terminated prematurely because adverse events six (1.6%). No occurred within first 15 min infusion. Premedication (in 24%) not associated with fewer events. Fear should inhibit use total dose practices premedication medical supervision during be abandoned.
Unplanned hospital readmissions are a quality and safety indicator. In Australian, 8% to 11.1% of unplanned occur ≤1 day acute care discharge. The aim this study was explore the reasons for discharge, determine what proportion such were potentially preventable. A retrospective exploratory cohort design used conduct two phase study. Phase 1, organisational data from 170 1358 between 2 28 days compared using Cochran-Mantel-Haenszel test. Binary logistic regression examine factors associated...
Abstract Background Demand for inpatient beds is increasing whilst supply diminishing. General medical services are feeling this demand as the ageing population presents more patients with undifferentiated illness traditionally cared by service. Redesign efforts need to focus on improving quality and speed of decision‐making utilise resources efficiently. Aims The aim study was improve patient flow through general undertaking a comprehensive redesign process targeting each stage journey....
BackgroundHealthcare workers (HCW) are exposed to an increased risk of COVID-19 through direct contact with patients and patient environments. We calculated the; seroprevalence SARS-CoV-2 in HCW at Eastern Health, a tertiary healthcare network Victoria, assessed associations demographics, work location role.MethodsA cross-sectional cohort study Health was conducted. Serum analysed for the presence antibodies SARS-CoV-2, all participants completed; online survey collecting information on...
Abstract Background Communication is pivotal to the effective care and treatment of patients in our health systems. Despite this understanding, clinicians are not sufficiently educated confidently conduct complex discussions with patients. skills workshops have been shown be an educational format improve clinician skills. However, despite increasing interprofessional focus within modern medicine, there few studies looking at communication workshops. Methods A qualitative study was conducted...