- Advanced Proteomics Techniques and Applications
- Metabolomics and Mass Spectrometry Studies
- Mass Spectrometry Techniques and Applications
- Influenza Virus Research Studies
- Viral Infections and Vectors
- Viral Infectious Diseases and Gene Expression in Insects
- S100 Proteins and Annexins
- 3D Printing in Biomedical Research
- Wound Healing and Treatments
- Aquaculture disease management and microbiota
- Respiratory viral infections research
- Burn Injury Management and Outcomes
- Animal Virus Infections Studies
- Immune Response and Inflammation
Technical University of Denmark
2021-2024
Viral Nervous Necrosis (VNN, also called viral encephalo- and retinopathy (VER)), is a widespread disease of marine aquaculture caused by betanodavirus (or nervous necrosis virus - NNV), segmented positive sense RNA virus, member the nodaviridae family. VNN affects predominantly fish cause significant losses to Mediterranean farming industry, including production European sea bass (Dicentrarchus labrax). Of four circulating genotypes betanodavirus, red-spotted grouper NNV (RGNNV) reassortant...
Venous leg ulcers represent a clinical challenge and impair the quality of life patients. This study examines impaired wound healing in venous at molecular level. Protein expression patterns for biomarkers were analysed ulcer fluids from 57 patients treated with protease-modulating polyacrylate dressing 12 weeks, compared exudates 10 acute split-thickness wounds. Wound improved wounds: 61.4% achieved relative area reduction ≥ 40%, 50.9% total 60%. Within first 14 days, abundances S100A8,...
Introduction Influenza A virus (IAV) infection is a global respiratory disease, which annually leads to 3-5 million cases of severe illness, resulting in 290,000-650,000 deaths. Additionally, during the past century, four IAV pandemics have claimed millions human lives. The epithelial lining trachea plays vital role infection, both as point viral entry and replication well antiviral immune response. Tracheal tissue generally inaccessible from patients, makes animal models crucial for study...
Targeted proteomics methods have been greatly improved and refined over the last decade are becoming increasingly method of choice in protein peptide quantitative assays. Despite tremendous progress, targeted assays still suffer from inadequate sensitivity for lower abundant proteins throughput, especially complex biological samples. These attributes essential establishing at forefront clinical use. Here, we report an assay utilizing SureQuantTM internal standard triggered on a newest...
The authors have withdrawn their manuscript whilst they perform additional analyses to test some of conclusions further. Therefore, the do not wish this work be cited as reference for project. If you any questions, please contact corresponding author ( uadk@dtu.dk ).