- Musculoskeletal pain and rehabilitation
- Spinal Fractures and Fixation Techniques
- Liver physiology and pathology
- Scoliosis diagnosis and treatment
- Medical Imaging and Analysis
- Pancreatic function and diabetes
- Amyotrophic Lateral Sclerosis Research
- Neurological diseases and metabolism
- Pain Management and Placebo Effect
- Alzheimer's disease research and treatments
- Organ Transplantation Techniques and Outcomes
- Pain Mechanisms and Treatments
University of Colorado Denver
2023
University of Colorado Anschutz Medical Campus
2021
Mayo Clinic in Florida
2017
Miami University
2017
A growing body of evidence suggests that a loss chromosome 9 open reading frame 72 (C9ORF72) expression, formation dipeptide-repeat proteins, and generation RNA foci contribute to disease pathogenesis in amyotrophic lateral sclerosis frontotemporal dementia. Although the levels C9ORF72 transcripts proteins have already been examined thoroughly, much remains unknown about role C9ORF72-linked diseases. As such, we performed comprehensive study an extensive pathological cohort expansion...
The role of fluid stresses in activating the hepatic stem/progenitor cell regenerative response is not well understood. This study hypothesized that immediate early genes (IEGs) with known links to liver regeneration will be upregulated progenitor cells (LPCs) exposed vitro shear on order those produced from elevated interstitial flow after partial hepatectomy. objectives were: (1) develop a chamber for application stress LPCs 3D culture; and (2) determine effects IEG expression LPCs. Two...