- RNA Interference and Gene Delivery
- Advanced biosensing and bioanalysis techniques
- Catalytic Processes in Materials Science
- Advanced Photocatalysis Techniques
- Covalent Organic Framework Applications
- Polymer Surface Interaction Studies
- Virus-based gene therapy research
- TiO2 Photocatalysis and Solar Cells
- Supercapacitor Materials and Fabrication
- Internet Traffic Analysis and Secure E-voting
- Advanced Sensor and Energy Harvesting Materials
- Advanced battery technologies research
- Extraction and Separation Processes
- Dermatologic Treatments and Research
- Nanopore and Nanochannel Transport Studies
- Polydiacetylene-based materials and applications
- Biopolymer Synthesis and Applications
- 3D Printing in Biomedical Research
- Nanowire Synthesis and Applications
- Biochemical effects in animals
- Quantum-Dot Cellular Automata
- CO2 Reduction Techniques and Catalysts
- Immunotherapy and Immune Responses
- Adsorption and biosorption for pollutant removal
- Fuel Cells and Related Materials
National Chin-Yi University of Technology
2021-2024
National Yang Ming Chiao Tung University
2023-2024
National Sun Yat-sen University
2021
National Pingtung University of Science and Technology
2013
National Taiwan University
2007-2011
Fooyin University
2009
Industrial wastewater often contains heavy metals, like lead, copper, nickel, cadmium, zinc, mercury, arsenic, and chromium. Overdoses of metals will impose a severe threat to human health. Adsorption is the most efficient way treatment for eliminating metals. A novel material-reusable hydrogel-based adsorbent was developed in overcoming regeneration issue. The polyethylene glycol diacrylate-3-sulfopropyl methacrylate potassium salt (PEGDA-SMP) hydrogel performed an ion-exchange rate remove...
DNA vaccination is a novel immunization strategy that possesses many potential advantages over other vaccine strategies. One of the major difficulties hindering clinical application relative poor immunogenicity vaccines. Poly(methyl methacrylate) (PMMA) synthetic polymer approved by Food and Drug Administration for certain human applications such as bone cement. In vivo, PMMA particles are phagocytosable have to initiate strong immune responses stimulating production inflammatory cytokines....
In this study, we develop the optimum composition of copper oxide/ruthenium oxide and multi-walled carbon nanotubes (CuO/RuO2/MWCNTs) ternary nanocomposite via a hydrothermal method as an efficient electrode material for supercapacitor applications. The ratio between CuO RuO2 varied to improve electrochemical performance electrode. synthesized nanocomposites are analyzed by high-resolution scanning electron microscopy (HR-SEM), thermo gravimetric analyzer (TGA) impedance spectroscopy (EIS)....
In an attempt to improve the photocatalytic activity of anatase TiO2, we developed a composite photocatalyst composed hollow TiO2 microspheres (hTS) and graphene. The hTS were prepared through two-step hydrothermal process, where SiO2 with desirable diameters 100–400 nm used as sacrificial templates. Accordingly, effect cavity size on catalyst in wet CO2 photoreduction (CO2PR) was studied. Furthermore, it established that pH value crucially influences photocatalyst, well its composition...
A variable gene delivery system has been developed based on conjugating chitosan to biotin through a functionalized poly(ethylene glycol) (PEG) spacer, which can be used further bind different molecules the outer layer of polymer/DNA complex by streptavidin (SA)-biotin linkage. In this study, TAT-conjugated SA was as model molecule prove conjugation function prepared complex. addition, low-molecular-weight poly(ethyleneimine) (PEI) added into increase transfection efficiency. The results...
Abstract In this study, we modified poly(ethylene‐ co ‐vinyl alcohol) (EVAL) membranes by the covalent bonding of diamines via epoxidation surface hydroxyl groups EVAL to analyze effect immobilized with different carbon chain length on cultured cerebellar granule neurons. Morphological studies showed that neurons seeded diamine‐immobilized membrane were able survive and regenerate formation an extensive neuritic network. Furthermore, presence diamine was effectively regulate neuron adhesion,...
A composite of highly dispersed Pt–RuO u –SnO v nanoparticles (NPs) on a mesoporous carbon CMK-3 framework was synthesized. The resulting composites Pt, RuO , SnO and were designated PwRxSy/C3, their microstructures compositions systematically characterized using variety techniques. Pt-based NPs have average particle sizes 2–8 nm well in the pore channels host. methanol oxidation reaction (MOR) activity catalysts investigated as function Sn mass fraction. electrochemical for MOR improved...
A novel cationic co-polymer was developed by grafting poly(ethylene glycol) (PEG) on guanidinylated polyallylamine (PAA) for gene delivery. Characterization of PEG-g-guanidinylated PAA/DNA complexes demonstrated that particle size increased and surface charge decreased with increasing the amount PEG. The results cytotoxicity assay proved grafted PEG could effectively decrease complexes. In transfection efficiency assay, HeLa cells treated PEG(2)-g-guanidinylated PAA (formed 17.5 μmol 2...
The application of technique assembling oligonucleotides (5'-C <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">10</sub> A xmlns:xlink="http://www.w3.org/1999/xlink">20</sub> -3') with binay polyethylene imine (PEI)/DNA complexes used to prepare a ternary anioic gene delivery system. Characterization PEI/DNA/oligonucleotide demonstrated that nanoparticles possessed the negative surface charge -50 mV and size around 100-170 nm when molar ratio...
Copolymers of 3-hydroxyvalerate (HV) and 3-hydroxyhexanoate (HHx) membranes are a new family biomaterials for tissue engineering applications. The object this study is to investigate the behavior rat tooth germ cells on various 3-hydroxyl-butyrate-co-3-hydroxy-hexanoate (PHBHHx) membranes. In study, PHBHHx from three thin-film processes were used. with different surface morphologies prepared by phase inversion, electrospinning, hot pressing. investigated scanning electron microscopy (SEM)....
Extensive atomistic simulations of the mechanical deformation defective nanowires (NWs) were performed using embedded-atom molecular dynamics modeling approach. The investigation focuses on coupled effects various vacancy cluster (VC) defects, operation temperature, and wire cross-sectional area properties plastic deformations NWs. stress-strain behaviors show that elastic modulus is independent defects. Quasi-linear decreasing Young's moduli observed with increasing temperature. For a given...