A5009596532- Hepatitis C virus research
- Advanced Materials Characterization Techniques
- Asymmetric Synthesis and Catalysis
- Monoclonal and Polyclonal Antibodies Research
- Fluorine in Organic Chemistry
- Synthetic Organic Chemistry Methods
- Chemical Synthesis and Analysis
- Microstructure and Mechanical Properties of Steels
- Phytochemical compounds biological activities
- High Temperature Alloys and Creep
- Synthesis and Biological Evaluation
- HIV/AIDS drug development and treatment
- Chemical synthesis and alkaloids
- Hepatitis B Virus Studies
- Nanoporous metals and alloys
- High Entropy Alloys Studies
- Crystallization and Solubility Studies
- Hydrogen embrittlement and corrosion behaviors in metals
- Fusion materials and technologies
- Microbial Natural Products and Biosynthesis
- Biochemical and Molecular Research
- Systemic Lupus Erythematosus Research
- Carbohydrate Chemistry and Synthesis
- Additive Manufacturing Materials and Processes
- Advancements in Battery Materials
Max-Planck-Institut für Nachhaltige Materialien
2022-2024
RWTH Aachen University
2017-2021
King George's Medical University
1989-2014
Abstract As hydrogen is touted as a key player in the decarbonization of modern society, it critical to enable quantitative (H) analysis at high spatial resolution and, if possible, atomic scale. H has known deleterious impact on mechanical properties (strength, ductility, toughness) most materials that can hinder their use part infrastructure hydrogen-based economy. Enabling mapping including local concentration analyses specific microstructural features essential for understanding multiple...
Objectives: To evaluate and compare the efficacy safety of Intranasal (IN) Dexmedetomidine, Midazolam Ketamine in producing moderate sedation among uncooperative pediatric dental patients. Study Design: This randomized triple blind comparative study comprises eighty four ASA grade I children both sexes aged 4-14 years, who were could not be managed by conventional behavior management techniques. All to receive one drug groups Dexmedetomidine 1?g/ kg (D1), 1.5μg/kg (D2), 0.2mg/kg (M1) 5mg/kg...
The purpose of present study was to evaluate the safety and efficacy orally administered midazolam in children as a sedative agent compare it with two other older agents, triclofos promethazine. conducted on ninety child patients requiring some short dental procedure. All were good physical status (ASA-I). ages ranged between 3 9 years. randomized into three groups: Group 1, midazolam, II, III, promethazine, basis drugs be administered. After administration each group, effects evaluated...
The impact of phase transformation from spinel-structured Li4Ti5O12 to rocksalt-type Li7Ti5O12 on the electrochromic properties material is studied. Thin films are deposited platinum-coated substrates using radio-frequency-ion beam sputtering. In situ and ex optical spectroscopy (in reflectance geometry) performed along with electrochemical characterization. measurements demonstrate reversible behavior thin effect change lithium content spectrum. Ex quantify constants for different charge...
Abstract The dependence of phase formation and mechanical properties on the chemical composition has been investigated for Pt-Ir Pt-Au combinatorial thin films. a single, metastable solid solution observed all experimental compositions temperatures. Upon Ir addition to Pt experimentally determined changes in lattice parameter Young’s modulus display rule mixture behavior which is good agreement with our ab initio data. Whereas, system, single decomposes into two phases as growth temperature...
Abstract The development of sustainable transportation and communication systems requires an increase in both energy density capacity retention Li‐batteries. Using substrates forming a solid solution with body‐centered cubic Li enhances the cycle stability anode‐less batteries. However, it remains unclear how substrate microstructure affects lithiation behavior. Here, correlative, near‐atomic scale probing approach is deployed through combined ion‐ electron‐microscopy to examine distribution...
Abstract Magnesium-based lightweight structural materials exhibit potential for energy savings. However, the state-of-the-art quest novel compositions with improved properties through conventional bulk metallurgy is time, energy, and material intensive. Here, opportunities provided by combinatorial thin film design sustainable development of magnesium alloys are evaluated. To characterise impurity level (Mg,Ca) solid solution films within grains grain boundaries, scanning transmission...
Abstract Cryogenic atom probe tomography (cryo-APT) is being developed to enable nanoscale compositional analyses of frozen liquids. Yet, the availability readily available substrates that allow for fixation liquids while providing sufficient strength their interface still an issue. Here, we propose use 1–2-µm-thick binary alloy film gold–silver sputtered onto flat silicon, with adhesion without additional layer. Through chemical dealloying, successfully fabricate a nanoporous substrate,...
Quantitative analysis of microstructural features on the nanoscale, including precipitates, local chemical orderings (LCOs) or structural defects (e.g. stacking faults) plays a pivotal role in understanding mechanical and physical responses engineering materials. Atom probe tomography (APT), known for its exceptional combination sensitivity sub-nanometer resolution, primarily identifies microstructures through compositional segregations. However, this fails when there is no significant...
Background: Current hepatitis C virus (HCV) therapies may cure ∼60% of infections. They are often contraindicated or poorly tolerated, underscoring the need for safer and more effective drugs. A novel, α-ketoamide-derived, substrate-based inhibitor HCV serine protease (SCH446211) was developed. Compared with earlier reported inhibitors similar chemical class, it has a P1′–P2′ extension which provides extended interaction active site. The aim this study to evaluate in vitro antiviral activity...
Thermal conductivity of NbO is studied experimentally and theoretically. Sputtered samples, slightly overstoichiometric in oxygen, are x-ray amorphous with a combined NbO2 short-range order, which consistent the quantum mechanical data. Upon annealing, crystallites form matrix due to an energetic preference 44 meV atom−1 over counterparts. The measured thermal at room temperature using time-domain thermoreflectance 6.9 W m−1 K−1, followed by continuous increase electronic contributions, it...