A5090924454- Receptor Mechanisms and Signaling
- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
- Cannabis and Cannabinoid Research
- Mast cells and histamine
- Olfactory and Sensory Function Studies
- Neuropeptides and Animal Physiology
- Neuroscience of respiration and sleep
- Neuroendocrine regulation and behavior
- Nicotinic Acetylcholine Receptors Study
- Sleep and Wakefulness Research
- Nitric Oxide and Endothelin Effects
- Ion channel regulation and function
- Asthma and respiratory diseases
- Pharmacological Receptor Mechanisms and Effects
- Pharmacological Effects and Assays
- Pain Mechanisms and Treatments
- Circadian rhythm and melatonin
- Alcohol Consumption and Health Effects
- Diet, Metabolism, and Disease
- Pulmonary Hypertension Research and Treatments
- Eicosanoids and Hypertension Pharmacology
- Heart Rate Variability and Autonomic Control
- Forensic Toxicology and Drug Analysis
- Retinal Development and Disorders
University of Bonn
2015-2025
University of Milan
2016
University of Würzburg
2016
University of Cologne
2016
Life & Brain (Germany)
2007-2016
Medical University of Białystok
1992-2012
October 6 University
1997
Institute of Pharmacology
1984-1991
Beiersdorf (Germany)
1990
University of California, San Diego
1990
Allergic contact dermatitis affects about 5% of men and 11% women in industrialized countries is one the leading causes for occupational diseases. In an animal model cutaneous hypersensitivity, we show that mice lacking both known cannabinoid receptors display exacerbated allergic inflammation. contrast, fatty acid amide hydrolase–deficient mice, which have increased levels endocannabinoid anandamide, displayed reduced responses skin. Cannabinoid receptor antagonists inflammation, whereas...
We investigated the influence of cannabidiol (CBD) on blood pressure (BP) and heart rate (HR) in spontaneously (SHR) deoxycorticosterone (DOCA-salt) hypertensive rats. Hypertension was connected with increases cardiac plasma markers lipid peroxidation both models, whereas endocannabinoid levels decreased SHR increased DOCA-salt. CBD (10 mg/kg once a day for 2 weeks) did not modify BP HR hypertension but counteracted pro-oxidant effects. Moreover, it or anandamide, 2-arachidonoylglycerol...