A5101487569- Neurological diseases and metabolism
- RNA regulation and disease
- Mitochondrial Function and Pathology
- Endoplasmic Reticulum Stress and Disease
- Parkinson's Disease Mechanisms and Treatments
- Folate and B Vitamins Research
- Nuclear Structure and Function
- Erythrocyte Function and Pathophysiology
- Cell death mechanisms and regulation
University of Chile
2009-2025
Buck Institute for Research on Aging
2019-2025
Harvard University
2018-2021
Center for Climate and Resilience Research
2019-2021
Abstract Parkinson’s disease (PD) is the second most common neurodegenerative condition, characterized by motor impairment due to progressive degeneration of dopaminergic neurons in substantia nigra and depletion dopamine release striatum. Accumulating evidence suggest that axons an early event disease, involving destruction programs are independent survival cell soma. Necroptosis, a programmed death process, emerging as mediator neuronal loss models diseases. Here, we demonstrate activation...