A5065479909- Essential Oils and Antimicrobial Activity
- Piperaceae Chemical and Biological Studies
- Phytochemistry Medicinal Plant Applications
- Insect Pest Control Strategies
- Phytochemical compounds biological activities
- Traditional and Medicinal Uses of Annonaceae
- Natural Compound Pharmacology Studies
- Natural product bioactivities and synthesis
- Research on Leishmaniasis Studies
- Natural Antidiabetic Agents Studies
- Phytochemistry and Biological Activities
- Plant biochemistry and biosynthesis
- Ethnobotanical and Medicinal Plants Studies
- Agricultural and Food Sciences
- Trypanosoma species research and implications
- Sesquiterpenes and Asteraceae Studies
- Botanical Research and Applications
- Healthcare Regulation
- Banana Cultivation and Research
- Bee Products Chemical Analysis
- Bioactive Compounds and Antitumor Agents
- Biochemical Analysis and Sensing Techniques
- Mosquito-borne diseases and control
- Antioxidant Activity and Oxidative Stress
- Biological and pharmacological studies of plants
Universidade Estadual de Maringá
2012-2021
Centro Universitário Cesumar
2014-2021
Centro de Ensino Superior de Juiz de Fora
2018
Fundação de Apoio a Pesquisa do Estado de Goiás
2015
Arab Foundations Forum
2014
University of Southern California
2010
European Union of Medical Specialists
2004-2008
University of California, San Francisco
2007
Universidade Federal de São Carlos
1992-2005
Istituto di Farmacologia Traslazionale
2005
Extracts of 13 Brazilian medicinal plants were screened for their antimicrobial activity against bacteria and yeasts. Of these, 10 plant extracts showed varied levels antibacterial activity. Piper regnellii presented a good Staphylococus aureus Bacillus subtilis, moderate on Pseudomonas aeruginosa, weak Escherichia coli. Punica granatum S. was inactive the other standard strains. Eugenia uniflora both E. Psidium guajava,Tanacetum vulgare, Arctium lappa, Mikania glomerata, Sambucus...
The essential oil (EO) of Ocimum gratissimum inhibited Staphylococcus aureus at a concentration 0.75 mg/ml. minimal inhibitory concentrations (MICs) for Shigella flexineri, Salmonella enteritidis, Escherichia coli, Klebsiella sp., and Proteus mirabilis were ranging from 3 to 12 <FONT FACE="Symbol">m</FONT>g/ml. endpoint was not reached Pseudomonas aeruginosa (>=24 mg/ml). MICs the reference drugs used in this study similar those presented other reports. minimum bactericidal EO within twofold...
The present study was designated to evaluate the antibacterial activities of aqueous and ethanol:water extracts from leaves, roots stem bark Psidium guajava L. against bacteria were tested by using both microdilution assay. P. active gram-positive Staphylococcus aureus (MICs=500, 125 250 µg/ml, respectively) Bacillus subtilis (MICs=500 µg/ml), virtually inactive gram-negative Escherichia coli Pseudomonas aeruginosa (MICs >1000 µg/ml). showed higher antimicrobial activity as compared...
The in vitro activity of parthenolide against Leishmania amazonensis was investigated. Parthenolide is a sesquiterpene lactone purified from the hydroalcoholic extract aerial parts Tanacetum parthenium. This isolated compound identified through spectral analyses by UV, infrared, (1)H and (13)C nuclear magnetic resonance imaging, DEPT (distortionless enhancement polarization transfer), COSY (correlated spectroscopy), HMQC (heteronuclear multiple-quantum coherence), electron spray...
This study tested in vitro activity of the essential oil from flowers Calendula officinalis using disk-diffusion techniques. The antifungal assay results showed for first time that has good potential activity: it was effective against all 23 clinical fungi strains tested.
Dermatophyte species infect the epidermis and appendages, often with serious social health-economic consequences. The hydroalcoholic extract of pomegranate fruit peel showed activity against dermatophyte fungi Trichophyton mentagrophytes, T. rubrum, Microsporum canis M. gypseum.Hydroalcoholic was prepared peels. This crude fractionated submitted to liquid-liquid partition, resulting in an active fraction which a Sephadex LH-20 column, followed by Lobar column. structure compound established...
The main objective of this work was to investigate the antifungal activity a crude extract, fractions and subfractions from Stryphnodendron adstringens (Mart.) Coville, known as 'barbatimão'.The growth inhibition by 'barbatimão' 103 isolates yeasts vaginal fluid determined using broth microdilution method. In addition, effect most active subfraction on cell surface hydrophobicity (CSH), germ-tube formation, budding, ultrastructure phagocytosis Candida albicans analysed. Fluconazole nystatin...
The seasonal variation of the chemical composition essential oil from fresh leaves Tetradenia riparia (Hochst.) Codd grown in southern Brazil was analyzed by GC-MS, and analgesic antimicrobial activities this were assayed. yield ranged 0.17% to 0.26%, with maximum amount winter minimum spring. results obtained principal components analysis (PCA) revealed existence high variability different seasons. samples clearly discriminated into three groups: winter, autumn, spring-summer. Samples...
Tetradenia riparia (Lamiaceae) is a well-known herbal medicine with variety of useful properties, including its acaricidal effect. This experiment was carried out to study the bioacaricidal activity T. essential oil (EO) against engorged females Rhipicephalus (Boophilus) microplus (Acari; Ixodidae). For this purpose, nine serial concentrations (12.50%, 6.25%, 3.75%, 1.80%, 0.90%, 0.45%, 0.22%, 0.11%, and 0.056% w/v) were used for adult immersion test (AIT). larval packet (LPT), we 14...
Essential oils from fresh Piperaceae leaves were obtained by hydrodistillation and analyzed gas chromatography mass spectrometry (GC-MS), a total of 68 components identified. Principal analysis results showed chemical variability between species, with sesquiterpene compounds predominating in the majority species analyzed. The composition essential oil Piper mosenii was described for first time. cytotoxicity evaluated peritoneal macrophages P. rivinoides, arboretum, aduncum exhibited highest...
This study describes the screening of extracts obtained from 19 species plants used in Brazilian traditional medicine for treatment a variety diseases. The were tested against axenic amastigote and promastigote forms Leishmania (L.) amazonensis, epimastigote Trypanosoma cruzi vitro at concentration 100 mg/ml. Baccharis trimera, Cymbopogon citratus, Matricaria chamomilla, Mikania glomerata, Ocimum gratissimum, Piper regnellii, Prunus domestica, Psidium guajava, Sambucus canadensis,...
Extracts from the dried pericarp of Sapindus saponaria L. (Sapindaceae) fruits were investigated for their antifungal activity against clinical isolates yeasts Candida albicans and C. non-albicans vaginal secretions women with Vulvovaginal Candidiasis. Four albicans, a single isolated each species parapsilosis, glabrata, tropicalis, strain ATCC 90028 used. The hydroalcoholic extract was bioactivity-directed isolate showed strong activity. n-BuOH one fraction all tested. Further...
The in vitro antiproliferative effects of 4 neolignans purified from the ethyl-acetate extract leaves Piper regnellii (MIQ.) C. DC. var. pallescens (C. DC.) YUNCK against Trypanosoma cruzi were investigated. These isolated compounds identified through spectral analyses UV, EI-MS, 1H-, 13C-NMR, H–H COSY, gNOE, HETCOR, and HMBC. eupomatenoid-5, eupomatenoid-6, conocarpan showed considerable activity epimastigote forms T. cruzi, with 50% inhibition concentrations (IC50) 7.0, 7.5, 8.0 μg/ml...
Arrabidaea chica leaf extract has been used by people as an anti-inflammatory and astringent agent well a remedy for intestinal colic, diarrhea, leucorrhea, anemia, leukemia. A. is known to be good producer of phenolics. Therefore, in the present study, we investigated its antioxidant activity. The phenolic composition leaves was studied liquid chromatography coupled diode array detection (LC-DAD) electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS), isoscutellarein,...
Many infections worldwide are associated with bacterial biofilms. The effects of isolated neolignans (conocarpan and eupomathenoid-5) the dichloromethane extract Piper regnellii (Miq.) C. DC., Piperaceae, were tested against isolates methicillin-resistant Staphylococcus aureus methicillin-sensitive S. biofilms planktonic cells. presented better results than all tested, a minimum inhibitory concentration <400 μg/ml for preformed minimal biofilm 15.6 formation. to cells was <12.5 μg/ml. These...
The evaluation of the activity aqueous and ethyl acetate extracts leaves Piper regnellii was tested against gram-positive gram-negative bacteria. extractdisplayed a weak Staphylococcus aureus Bacillus subtilis with minimal inhibitory concentration (MIC) bactericidal (MBC) 1000 µg/ml. extract presented good S. B. MIC MBC at 15.62 In contrast to relative low MICs for bacteria, bacteria were not inhibited by concentrations < mg/ml. fractionated on silica gel into nine fractions. hexane...
The global resurgence of tuberculosis (TB) and the development drug resistance, as multidrug-resistant (MDR) extensively drug-resistant (XDR) Mycobacterium isolates, are a threat to TB control have created need for new more effective anti-TB drugs.The current study evaluated in vitro cytotoxicity activity Tetradenia riparia essential oil (TrEO) 6,7-dehydroroyleanone pure compound against M. H37Rv susceptible resistant clinical isolates.The activities TrEO were determined by Resazurin...