A5100762707- Epigenetics and DNA Methylation
- Genetic Syndromes and Imprinting
- Genetic Associations and Epidemiology
- Nutritional Studies and Diet
- Birth, Development, and Health
- Nutrition and Health in Aging
- Congenital heart defects research
- Health, Environment, Cognitive Aging
- Liver Disease Diagnosis and Treatment
- Trace Elements in Health
- Folate and B Vitamins Research
- Heavy Metal Exposure and Toxicity
- Gestational Diabetes Research and Management
- Obesity, Physical Activity, Diet
- Nutrition, Genetics, and Disease
- Genetics and Neurodevelopmental Disorders
- Diet and metabolism studies
- Cancer, Lipids, and Metabolism
- Cancer-related gene regulation
- Pregnancy and preeclampsia studies
- Acute Ischemic Stroke Management
- Gout, Hyperuricemia, Uric Acid
- Maternal and fetal healthcare
- Blood Pressure and Hypertension Studies
- Ectopic Pregnancy Diagnosis and Management
Qingdao University
2016-2025
Shanghai Jiao Tong University
2022-2024
Ruijin Hospital
2022-2024
Lanzhou University Second Hospital
2024
Chinese Academy of Agricultural Mechanization Sciences
2024
Lanzhou University
2024
University of Edinburgh
2024
Shantou University Medical College
2023-2024
Wuxi People's Hospital
2024
Nanjing Medical University
2024
Abstract Plant extracts contain many active compounds, which are tremendously fruitful for plant defence against several insect pests. The prime objectives of the present study were to calculate extraction yield and evaluate leaf Citrullus colocynthis (L.), Cannabis indica (L.) Artemisia argyi Brevicoryne brassicae conduct biochemical analysis by gas chromatography-mass spectrometry (GC-MS). results suggested that when using ethanol, C. produced a high dry (12.45%), followed A. , 12.37%...
// Zeran Wang 1,2,* , Yueyong Liu 1,* Pengju Zhang 3,1,* Weiguo 1 Weijing 1,4 Kenneth Curr 2 Guangwei Wei 5,1 Jian-Hua Mao Life Sciences Division, Lawrence Berkeley National Laboratory, One Cyclotron Road, Berkeley, CA, USA Department of Biology, California State University East Bay, Hayward, California, USA. 3 Biochemistry and Molecular Shandong School Medicine, Jinan, Shandong, China 4 Cell 5 Anatomy, Building 1, P.R. * These authors contributed equally to this paper. Correspondence: Mao,...
Abstract Depression is currently the leading cause of disability around world. We conducted an epigenome-wide association study (EWAS) in a sample 58 depression score-discordant monozygotic twin pairs, aiming to detect specific epigenetic variants potentially related and further integrate with gene expression profile data. Association between methylation level each CpG site score was tested by applying linear mixed effect model. Weighted co-expression network analysis (WGCNA) performed for...
As life expectancy increases, cognitive performance decline in the elderly has become one of major global challenges. We aimed to evaluate association dietary vitamin D (VD), serum 25-hydroxyvitamin D3 (25(OH)D3), D2 (25(OH)D2), and total (25(OH)D) concentration with older Americans. The data from National Health Nutrition Examination Survey (NHANES), 2011-2014 was used. assessed by Consortium Establish a Registry for Alzheimer's Disease (CERAD) Word Learning sub-test, Animal Fluency test,...
Previous genome-wide association studies on anthropometric measurements have identified more than 100 related loci, but only a small portion of heritability in obesity was explained. Here we present bivariate twin study to look for the genetic variants associated with body mass index and waist-hip ratio, explore obesity-related pathways Northern Han Chinese. Cholesky decomposition model 242 monozygotic 140 dizygotic pairs indicated moderate correlation (r=0.53, 95%CI: 0.42-0.64) between...
The therapeutic management of obesity is challenging, hence further elucidating the underlying mechanisms development and identifying new diagnostic biomarkers targets are urgent necessary. Here, we performed differential gene expression analysis weighted co-expression network (WGCNA) to identify significant genes specific modules related BMI based on profile data 7 discordant monozygotic twins. In analysis, it appeared that 32 differentially expressed (DEGs) were with a trend up-regulation...
The study used the data from National Health and Nutrition Examination Survey (NHANES) 2007–2014 to analyse relationship of dietary vitamin B1, B2, niacin, B6, B12 folate equivalent (DEF) intakes with metabolic syndrome. In multivariate-adjusted model 2, compared lowest quartile intake, odd ratios (ORs;95% confidence intervals (CIs)) were 0.73 (0.59–0.91), 0.76 (0.61–0.95), (0.59–0.98) 0.77 (0.62–0.96) for highest B6 DFE, respectively. ORs (95%CIs) third B2 0.78 (0.61–0.99) 0.62 (0.47–0.83)....
Thin endometrium (TE) is closely associated with infertility in reproductive medicine. Estrogen therapy gains unsatisfactory outcomes. In this study, an artificial mucus based on dopamine (L-DOPA)-modified hyaluronic acid combining phytoestrogen cajaninstilbene and rat urinary exosomes (CUEHD) constructed for TE treatment using a model. the model, dominant elastic behavior adhesive properties of CUEHD guarantee adequate retention, rendering superior synergistic efficacy favorable biosafety...
DNA methylation (DNAm) has been shown in multiple studies to be associated with the estimated glomerular filtration rate (eGFR). However, focusing on Chinese populations are lacking. We conducted an epigenome-wide association study investigate between DNAm and eGFR monozygotic twins. Genome-wide level was detected using Reduced Representation Bisulfite Sequencing test. Generalized estimation equation (GEE) used examine Cytosine-phosphate-Guanines (CpGs) eGFR. Inference about Causation from...
Several modifiable health factors in Life's Essential 8 (LE8) are linked to nutritional anemia and can assess overall cardiovascular (CVH). This study explored the associations of CVH measured by LE8 score with iron deficiency (IDA), including mediating role inflammatory biomarkers. prospective cohort included 181,069 participants from UK Biobank. was categorized into low (0–49), medium (50–79), high (80–100) based on score. Weibull regression models were used quantify association between...