A5032509096- Effects of Radiation Exposure
- Biomarkers in Disease Mechanisms
- Inflammasome and immune disorders
The First Affiliated Hospital, Sun Yat-sen University
2022
Sun Yat-sen University
2022
Zhongshan Hospital
2022
Fudan University
2022
Immune checkpoint inhibitors (ICIs)-related myocarditis is now one of the most critical immune-related adverse effects (irAEs) in tumor immunotherapy, which has raised great concern cardio-oncology. The pathogenesis involved cardiac injury remains elusive. Crocin, main component saffron, shown distinct functions cardioprotective and anti-inflammation properties. We therefore aimed to investigate potential effect crocin on protection ICIs-related its underlying molecular mechanism.We...