- Congenital Diaphragmatic Hernia Studies
- Tracheal and airway disorders
- Neonatal Respiratory Health Research
- Esophageal and GI Pathology
- Congenital Anomalies and Fetal Surgery
- Gastrointestinal disorders and treatments
- Hernia repair and management
- Foreign Body Medical Cases
- Pediatric Hepatobiliary Diseases and Treatments
- Gastroesophageal reflux and treatments
- Appendicitis Diagnosis and Management
- Intestinal and Peritoneal Adhesions
- Intestinal Malrotation and Obstruction Disorders
- Restraint-Related Deaths
- Eosinophilic Esophagitis
- Genital Health and Disease
- Fetal and Pediatric Neurological Disorders
- Tumors and Oncological Cases
- Diverticular Disease and Complications
- Medical Imaging and Pathology Studies
- Spinal Dysraphism and Malformations
- Cardiac, Anesthesia and Surgical Outcomes
- Intraperitoneal and Appendiceal Malignancies
- Soft tissue tumor case studies
- Helicobacter pylori-related gastroenterology studies
Cincinnati Children's Hospital Medical Center
2016-2024
Namık Kemal University
2021-2024
Koç University
2018-2023
University of Health Sciences Antigua
2022
Sağlık Bilimleri Üniversitesi
2022
Biruni University
2022
Istanbul Medipol University
2021
Boğaziçi University
2021
Cukurova University
2020
University of Cincinnati
2019
BackgroundCongenital anomalies are the fifth leading cause of mortality in children younger than 5 years globally. Many gastrointestinal congenital fatal without timely access to neonatal surgical care, but few studies have been done on these conditions low-income and middle-income countries (LMICs). We compared outcomes seven most common low-income, middle-income, high-income globally, identified factors associated with mortality.MethodsWe did a multicentre, international prospective cohort...
The Clavien-Madadi classification is a novel instrument for the assessment and grading of unexpected events in pediatric surgery, based on Clavien-Dindo classification. system has been adjusted to better fit population prospective single-center study. There need now validate within an international expert network.
Transition of care (TOC; from childhood into adulthood) patients with anorectal malformations (ARM) and Hirschsprung disease (HD) ensures continuation for these patients. The aim this international study was to assess the current status TOC adult (AC) programs ARM HD.A survey developed by members EUPSA, ERN eUROGEN, ERNICA, including patient representatives (ePAGs), comprising four domains: general information, questions about transition adulthood, disease-specific regarding AC programs....
Congenital diaphragmatic hernia (CDH) occurs in ~1:2,000 pregnancies and is associated with substantial morbidity mortality. Fetal tracheal occlusion (TO) an emerging therapy that improves lung growth reduces mortality, although respiratory compromise persists survivors. In this study, we used fluid a fetal sheep model of CDH TO for proteomic analysis subsequent validation findings tissue. We found the profiles was most similar to control CDH/TO lung. Among 118 proteins altered CDH, only 11...
The failure of a fetus to develop its full potential due maternal or placental factors is known as intrauterine growth restriction (IUGR). Fetal head usually preserved in that situation producing discordance between and body size. Our goal discover if IUGR has an impact on the prenatal ultrasound measurements taken assess pulmonary development congenital diaphragmatic hernia (CDH).
Abstract Introduction Anastomotic stricture (AS) is the second most common complication after esophageal atresia (EA) repair. We aimed to evaluate data in Turkish Esophageal Atresia Registry determine risk factors for AS development EA repair a large national cohort of patients. Methods The between 2015 and 2021 were evaluated. Patients enrolled into two groups according occurrence AS. with (AS group) without (non-AS compared demographic operative features, postoperative intubation status,...
While appendiceal intussusception is an uncommon pathological condition, mucinous cystadenoma of the appendix a particularly rare entity. We report case induced by presenting as acute appendicitis. A 37-year-old woman was admitted with one-day history onset, right lower abdominal pain. Computed tomography showed swelling appendix, mass in ileocolic region and oedematous pericolonic fat stranding. Emergency laparotomy via McBurney incision revealed that base swollen intussuscepting into...
Intussusception, the second most common abdominal emergency in childhood, is three times more men, and peak age before 2 years.1–3 The incidence neonates 0.3–1.3 per 6000 cases.2–4 Till date, only 17 reports are available PubMed less than 50 cases English literature. Most of were misdiagnosed as necrotizing enterocolitis (NEC), causing a delay treatment. Herein, we present case, demonstrating how it important that an early diagnosis premature with nonspecific symptoms affects outcome.
Although intussusception and food allergy are common health problems in childhood, the relation between these two diseases remain obscure. The aim of this study is to investigate relationship intussusception, factors associated with both. Patients diagnosed by Brighton Collaboration Intussusception Working Group criteria were prospectively investigated for per European Society Pediatric Gastroenterology, Hepatology Nutrition (ESPGHAN) Guideline. They analyzed demographic features, clinical,...
Congenital band compression syndrome should be considered in cases diagnosed prenatally or postnatally as intestinal obstruction. Presently described is a report of newborn admitted to hospital with abdominal distension and bilious vomiting. A suspected obstruction had been prenatal examination. Surgery revealed congenital compressing ileal segments preventing transmission content. Band was successfully removed integrity intact.
Fetal endoscopic tracheal occlusion (FETO) is an emerging surgical therapy for congenital diaphragmatic hernia (CDH). Ovine and rabbit data suggested altered lung epithelial cell populations after (TO) with transcriptomic signatures implicating basal cells. To test this hypothesis, we deconvolved mRNA sequencing (mRNA-seq) used quantitative image analysis in fetal TO, which had increased cells reduced ciliated TO. In a mouse TO model, flow cytometry showed cells, immunohistochemistry...
To assess the feasibility of evaluating fetal cerebellar oxygenation in pregnant rats by Photoacoustics (PA) imaging on day 20 pregnancy (E20). PA is a real-time, non-invasive method, combining laser pulse tissue excitation and ultrasonic detection response. We conducted an experimental pilot study four rat fetuses, from two different that were scanned transabdominally E20 with system coupled to high-resolution ultrasound imaging. The Vevo 2100 LAZR used first identify cerebellum then its...
Recurrent intussusception is a management dilemma and have many causes. We report 22-month old boy who presented multiple times for recurrent intussusception. At diagnostic work-up he was found to be suffering from non-IgE food allergy. The child did not develop further episodes of after removal allergenic diet.
Comparative, functional, developmental, and some morphological studies on animal anatomy require accurate visualization of three-dimensional structures. Nowadays, several widely applicable methods exist for non-destructive whole-mount imaging tissues. The purpose this study was to optimize specimen preparation develop a method quantitative analysis the total pulmonary vasculature in fetal rats. Tissues were harvested at E21 fetuses fixed overnight 4% paraformaldehyde/phosphate buffered...
Tubularized incised plate urethroplasty (TIPU) surgery is among the most successful techniques for distal hypospadias. Our objective was investigation of complication rates and their predictors.Between 2010 2021, 150 patients with hypospadias were operated on consecutively by a single surgeon using TIPU technique. The primary outcome including fistula, meatal stenosis, glans dehiscence. Secondary outcomes predictor factors complications.The average diameter 13.9 ± 0.10 mm 57.0% had greater...