- Opioid Use Disorder Treatment
- Substance Abuse Treatment and Outcomes
- Pharmaceutical Practices and Patient Outcomes
- Health, Medicine and Society
- Healthcare Systems and Practices
- Pain Management and Opioid Use
- HIV, Drug Use, Sexual Risk
- Mental Health Treatment and Access
- Pain Management and Placebo Effect
- Child and Adolescent Psychosocial and Emotional Development
- Parkinson's Disease Mechanisms and Treatments
- Pharmaceutical studies and practices
- Maternal Mental Health During Pregnancy and Postpartum
- Blood Pressure and Hypertension Studies
- Forensic Toxicology and Drug Analysis
- Chronic Disease Management Strategies
- COVID-19 and Mental Health
- Cervical Cancer and HPV Research
- Schizophrenia research and treatment
- Sleep and related disorders
- COVID-19 Clinical Research Studies
- Social Policies and Family
- Adolescent and Pediatric Healthcare
- Primary Care and Health Outcomes
- Stroke Rehabilitation and Recovery
Université Toulouse III - Paul Sabatier
2016-2025
Inserm
2015-2024
Université de Toulouse
2015-2024
Centre d'Étude et de Recherche Travail Organisation Pouvoir
2021-2023
Centre de recherche en Epidémiologie et Santé des Populations
2022
Université de Strasbourg
2022
Hôpital Purpan
2011-2021
Centre d’Investigation Clinique 1436
2021
Hôpital Paule de Viguier
2021
Laboratoire Epidémiologie et Analyses en Santé Publique : Risques, Maladies Chroniques et Handicaps
2019-2020
Aims The aim of this study was to assess the use and factors associated with misuse gabapentin pregabalin in general French population, through a cohort EGB (General Sample Beneficiaries), national representative sample population. Methods New users were identified from June 2006 December 2014, new duloxetine served as control group. Misuse defined higher daily doses than recommended. Cox proportional hazard regression models performed identify misuse. Results more frequent 8692 (12.8%) 1963...
In France, most cases of opioid use disorder are treated with buprenorphine by general practitioners in private practice. Using reimbursement data a representative sample the French population, Echantillon Généraliste des Bénéficiaires, we investigated mortality during periods when patients were and out treatment cohort 713 new users having mean (SD) follow-up 4.5 (1.5) years. The rate was 0.63 per 100 person-years (95% CI, 0.40–0.85) overall. multivariate Cox regression model, compared...
To assess the efficacy of inhaled ciclesonide in reducing risk adverse outcomes COVID-19 outpatients at developing severe illness.COVERAGE is an open-label, randomized controlled trial. Outpatients with documented COVID-19, factors for aggravation, symptoms ≤7 days, and absence criteria hospitalization are randomly allocated to either a control arm or one several experimental arms, including ciclesonide. The primary endpoint worsening (hospitalization, oxygen therapy home, death) by Day 14....
Drugs administered to hospitalized patients are not available within almost all health insurance databases. However, this unobservable exposure time bias is very rarely taken into account in pharmacoepidemiology. The objective was model periods due hospitalization and assess their impact on risk estimates the context of association between benzodiazepines mortality.A cohort study identified using General Sample Beneficiaries France for period 2006-2012. Benzodiazepines incident users were...
<b><i>Background:</i></b> In France, most patients with opioid use disorder (OUD) have been treated by buprenorphine, prescribed general practitioners (GP) in private practice since 1996. This has contributed to building a ‘French model’ facilitating access treatment based on the involvement of GPs buprenorphine prescription. <b><i>Objectives:</i></b> Our study aimed assess whether primary care OUD management changed lately....
Drug-Drug Interactions between Non Steroidal Anti-Inflammatory Drugs (NSAIDs) and Angiotensin Converting Enzyme Inhibitors (ACEIs), Receptor Blocker (ARBs) or diuretics can lead to renal failure hyperkalemia. Thus, monitoring of serum creatinine potassium is recommended when a first dispensing NSAID occur in patients treated with these drugs.We conducted pharmacoepidemiological retrospective cohort study using data from the French Health Insurance Reimbursement Database evaluate proportion...
Background: Adverse events result in longer hospital stays and increase costs mortality.We aimed to assess incidence of adverse occurring during hospitalization a post-emergency unit describe their characteristics.Methods: All patients French university (20 beds) were systematically consecutively recorded from September 2009 February 2011.Patients with compared up three control patients, matched for date admission +/-age the same unit.Results: We identified 56 64 events, giving an 3.0/100...
The objective of this study was to describe the level knowledge about paracetamol (acetaminophen), ibuprofen, and aspirin subjects who purchased nonprescription medications containing one these drugs. We conducted cross-sectional descriptive in 42 community pharmacies located southwestern France between July November 2013. A six-item self-administered questionnaire used. Participants were asked identify active ingredient contained 14 brand-name analgesic-antipyretics, state maximum daily...
Teaching of medication prescribing is a specific challenge in general practice curriculum. The aim this study was to identify and rank the competencies required for residents France. Qualitative consensus using nominal group technique. We invited different stakeholders curriculum use primary care series meetings. technique allowed quick development list consensual ranked answers following question: "At end their curriculum, terms prescribing, what should be able do?". Four meetings were held...
Background Despite most GPs recognising their role in the early diagnosis of alcohol use disorder (AUD), only 23% routinely screen for use. One reason report not screening is relationship with patients; questions regarding are considered a disturbance built on mutual trust. Aim To analyse feelings and experiences patients AUD concerning by GPs. Design & setting A qualitative study ( n = 12) remission or treatment, recruited from various medical settings. Method Semi-structured interviews...