- HIV/AIDS Research and Interventions
- Adolescent Sexual and Reproductive Health
- HIV, Drug Use, Sexual Risk
- COVID-19 and healthcare impacts
- Global Maternal and Child Health
- COVID-19 Digital Contact Tracing
- COVID-19 and Mental Health
- COVID-19 epidemiological studies
- HIV/AIDS Impact and Responses
- Health and Medical Studies
- Influenza Virus Research Studies
- Emergency and Acute Care Studies
- COVID-19 Clinical Research Studies
- Sex work and related issues
- Data-Driven Disease Surveillance
- Telemedicine and Telehealth Implementation
- Electronic Health Records Systems
- Acute Ischemic Stroke Management
- Indoor Air Quality and Microbial Exposure
- Digital Mental Health Interventions
- Bacterial Infections and Vaccines
- Artificial Intelligence in Healthcare and Education
- HIV, TB, and STIs Epidemiology
- Zoonotic diseases and public health
- Respiratory viral infections research
Robert Koch Institute
2018-2024
Emory University
2023
Emory Healthcare
2021-2022
Cancer Care Ontario
2018
London School of Hygiene & Tropical Medicine
2013-2017
University of London
2013-2015
National Health Service
2011
Objectives To compare breadth of condition coverage, accuracy suggested conditions and appropriateness urgency advice eight popular symptom assessment apps. Design Vignettes study. Setting 200 primary care vignettes. Intervention/comparator For apps seven general practitioners (GPs): coverage condition-suggestion measured against the vignettes’ gold-standard. Primary outcome measures (1) Proportion ‘covered’ by an app, that is, not excluded because user was too young/old or pregnant,...
Abstract Introduction Longer intervals between clinic consultations for clinically stable antiretroviral therapy ( ART ) patients may improve retention in care and reduce facility workload. We assessed long‐term among attending six‐monthly clinical SMCC with three‐monthly fast‐track drug refills, estimated the number of “saved” by this model delivery rural Malawi. Methods Stable (aged ≥18 years, on first‐line ≥12 months, CD 4 count ≥300 cells/ mL 3 , without opportunistic infections, not...
Background Unprecedented lockdown measures have been introduced in countries worldwide to mitigate the spread and consequences of COVID-19. Although attention has focused on effects these epidemiological indicators relating directly infection, there is increased recognition their broader health implications. However, assessing implications real time a challenge, due limitations existing syndromic surveillance data tools. Objective The aim this study explore added value mobile phone app–based...
<h3>Objectives</h3> This study aimed to identify factors associated with access HIV care and antiretroviral (ARV) drugs for prevention of mother-to-child transmission (PMTCT) among HIV-positive pregnant women in a community cohort rural Tanzania (Kisesa). <h3>Methods</h3> Kisesa-resident who tested during serosurveillance were (while HIV-positive) between 2005 2012 eligible. Community records linked PMTCT clinic data from four facilities (PMTCT programme implemented 2009; referrals...
Background HIV counselling and testing (HCT) services can play an important role in prevention by encouraging safe sexual behaviours linking HIV-infected clients to antiretroviral therapy (ART). However, regular repeat high-risk HIV-negative individuals is for timely initiation of ART as part the ‘treatment prevention’ approach. Aim To investigate HCT use during a round serological surveillance northwest Tanzania 2010, explore rates between 2003 2010. Methods were provided fourth, fifth...
It is widely assumed that voluntary counselling and testing (VCT) services contribute to HIV prevention by motivating clients reduce sexual risk-taking. However, findings from sub-Saharan Africa have been mixed, particularly among HIV-negative persons. We explored associations between VCT use changes in risk behaviours incidence using data a community cohort study northwest Tanzania. Data on use, behaviour status were available three serological surveillance rounds undertaken 2003–4 (Sero4),...
The last decade has seen rapid evolution in guidance from the WHO concerning provision of HIV services along diagnosis-to-treatment continuum, but extent to which these recommendations are adopted as national policies Kenya, and subsequently implemented health facilities, is not well understood. Identifying gaps policy coverage implementation important for highlighting areas improving service delivery, leading better outcomes. We compared with testing counselling, prevention mother-to-child...
Abstract Background Despite the introduction of free antiretroviral therapy (ART), use voluntary counselling and testing (VCT) services remains persistently low in many African countries. This study investigates how prior experience HIV VCT, knowledge about ART influence VCT rural Tanzania. Methods In 2006–7, was offered to participants during fifth survey round an community cohort that includes for research purposes without results disclosure, a questionnaire covering knowledge, attitudes...
Estimates of population-level coverage with prevention mother-to-child transmission (PMTCT) services are vital for monitoring programmes but rarely undertaken. This study describes uptake PMTCT among HIV-positive pregnant women in a community cohort rural Tanzania. Kisesa incorporates demographic and HIV sero-surveillance rounds since 1994. Cohort data were linked retrospectively to records from four clinics 2009 (HIV care treatment clinic (CTC) available one facility 2008; referrals city...
Introduction Between 2021 and 2023, a project was funded in order to explore the mortality burden (YLL–Years of Life Lost, excess mortality) COVID-19 Southern Eastern Europe, Central Asia. Methods For each national or sub-national region, data on deaths population were collected for period March 2020 December 2021. Unstandardized age-standardised YLL rates calculated according standard disease methodology. In addition, all-cause 2015–2019 used as baseline estimate region years Results On...
Human T-lymphotropic virus (HTLV) infection is rare in the United Kingdom (UK) and few studies are available worldwide. Following introduction of blood donation testing 2002, a cohort individuals could be identified prospectively recruited to describe progression onset disease. Here we baseline characteristics participants, evaluate recruitment into UK HTLV National Register over first six years, from July 2003 June 2009. A multicentre study participants services (recipients donors)...
Voluntary counselling and testing (VCT) for HIV first evolved in Western settings, with one aim being to promote behaviours which lower the risk of onward transmission or acquisition HIV. However, although quantitative studies have shown that impact VCT on sexual behaviour change has been limited African there is a lack qualitative research exploring perceptions prevention messages, particularly among clients HIV-negative. We conducted study explore healthcare worker, community both...
Abstract Objectives To compare breadth of condition coverage, accuracy suggested conditions and appropriateness urgency advice 8 popular symptom assessment apps with each other 7 General Practitioners. Design Clinical vignettes study. Setting 200 clinical representing real-world scenarios in primary care. Intervention/comparator Condition accuracy, performance was measured against the vignettes’ gold-standard diagnoses triage level. Primary outcome measures Outcomes included (i) proportion...
To investigate the relative effectiveness of different HIV testing and counselling (HTC) services in improving diagnosis rates increasing HTC coverage African settings.Patient records from three [community outreach during cohort study rounds (CO-HTC), walk-in at local health centre (WI-HTC) antenatal (ANC-HTC)] were linked to a community using probabilistic record linkage algorithm. Characteristics users each service compared those participants who did not use logistic regression. Data...
Background Participatory epidemiology is an emerging field harnessing consumer data entries of symptoms. The free app Ada allows users to enter the symptoms they are experiencing and applies a probabilistic reasoning model provide list possible causes for these Objective objective our study explore potential contribution syndromic surveillance by comparing influenza-like illness (ILI) entered in Germany with from national population-based reporting system called GrippeWeb. Methods We...
The COVID-19 pandemic has had an extensive impact on public health worldwide. However, in many countries burden of disease indicators for have not yet been calculated or used monitoring. present study protocol describes approach developed the project "The Burden Disease due to COVID-19. Towards a harmonization population metrics surveillance dynamic outbreaks" (BoCO-19). process data collection and aggregation across 14 different sub-national regions Southern Eastern Europe Central Asia is...
<sec> <title>BACKGROUND</title> Unprecedented lockdown measures have been introduced in countries worldwide to mitigate the spread and consequences of COVID-19. Although attention has focused on effects these epidemiological indicators relating directly infection, there is increased recognition their broader health implications. However, assessing implications real time a challenge, due limitations existing syndromic surveillance data tools. </sec> <title>OBJECTIVE</title> The aim this study...
The term "community health worker" (CHW) can apply to a wide range of individuals providing services and support for diverse populations. Very little is known about the role CHWs in Europe working nonclinical settings who promote sexual prevent HIV other sexually transmitted infections (STIs) among gay, bisexual, men have sex with (MSM).
Abstract Background Unprecedented lockdown measures have been introduced in countries across the world to mitigate spread and consequences of COVID-19. While attention has focused on effects these epidemiological indicators relating directly infection, there is increased recognition their broader health implications. However, assessing implications real time a challenge, due limitations existing syndromic surveillance data tools. Objective To explore added value mobile phone app-based...
<h3>Introduction</h3> The COVID-19 pandemic has led to excess mortality out of proportion documented cases while also affecting the care non-COVID-19 related diseases. No data exist on effects and outcomes patients with aneurysmal subarachnoid hemorrhage (aSAH). Here we determine impact latency presentation clinical for hemorrhage. <h3>Methods</h3> We performed a retrospective cohort study all presenting single center in Atlanta, Georgia, USA aSAH between 2012 2020. was first reported...
<sec> <title>BACKGROUND</title> Participatory epidemiology is an emerging field harnessing consumer data entries of symptoms. The free app Ada allows users to enter the symptoms they are experiencing and applies a probabilistic reasoning model provide list possible causes for these </sec> <title>OBJECTIVE</title> objective our study explore potential contribution syndromic surveillance by comparing <i>influenza-like illness</i> (ILI) entered in Germany with from national...