A5102991899- Esophageal and GI Pathology
- Celiac Disease Research and Management
- Microscopic Colitis
- Pancreatic and Hepatic Oncology Research
- Glycosylation and Glycoproteins Research
- Gastric Cancer Management and Outcomes
- Abdominal Surgery and Complications
- Gastrointestinal disorders and treatments
- Pneumothorax, Barotrauma, Emphysema
- Inflammatory Bowel Disease
- Cancer Cells and Metastasis
- Biliary and Gastrointestinal Fistulas
- Protein purification and stability
- Cancer Genomics and Diagnostics
- Metastasis and carcinoma case studies
- Fungal Infections and Studies
- Bariatric Surgery and Outcomes
- Neuroendocrine Tumor Research Advances
- Antifungal resistance and susceptibility
- Monoclonal and Polyclonal Antibodies Research
- Immunodeficiency and Autoimmune Disorders
- Pancreatitis Pathology and Treatment
- Acute Lymphoblastic Leukemia research
- Cystic Fibrosis Research Advances
- Chronic Lymphocytic Leukemia Research
University of Chicago
2018-2020
University of Chicago Medical Center
2019
Lurie Children's Hospital
2015
Brigham and Women's Hospital
2013
Harvard University
2013
University of California, San Francisco
2001
Immunoglobulin G (IgG) Fc receptors play a critical role in linking IgG antibody-mediated immune responses with cellular effector functions. A high resolution map of the binding site on human IgG1 for FcγRI, FcγRIIA, FcγRIIB, FcγRIIIA, and FcRn has been determined. common set residues is involved to all FcγR; FcγRII FcγRIII also utilize outside this set. In addition which, when altered, abrogated one or more receptors, several were found that improved only specific simultaneously type...
To evaluate CD200 expression in B-cell proliferative disorders.We analyzed 180 recent specimens of neoplasms for by flow cytometric immunophenotypic analysis, which is better able to assess relative intensity staining than immunohistochemical staining.We found that hairy cell leukemia exhibits a high level comparison other lymphoproliferative disorders, including leukemia-variant (HCL-V), marginal zone lymphoma, and lymphoplasmacytic lymphoma. We confirmed this observation semiquantitative...
Background Bronchoscopy with bronchoalveolar lavage (BAL) and respiratory tract biopsies are important tools for diagnosing fungal infections in children cancer hematopoietic stem cell transplant (HSCT) recipients. Our objective was to evaluate the impact of BAL on management suspected oncology HSCT patients. Procedure We retrospectively reviewed medical records patients possible, probable, or proven infection determined whether biopsy following computed tomography (CT) prompted a change...
Enterocutaneous fistulas (ECFs) are associated with considerable morbidity and mortality. Most ECFs occur after surgery, but other causes include infection, perforated peptic ulcer, inflammatory bowel disease, even abdominal injury or trauma. The management of an ECF is often protracted complex. When initial medical fails, nonsurgical interventions limited have disappointing outcomes. Fistula plugs been used some success in anorectal fistulas. Although there experience fistula for closure,...
Introduction Cyclophosphamide (CPM) is one of the oldest chemotherapeutic agents available, which also has immunosuppressive properties. It was first used for inflammatory bowel disease (IBD) in 1985, when given to 4 patients who developed pancreatitis on azathioprine. The case series using pulse IV CPM steroid-refractory IBD described 2003. Case presentation We describe a 23-year-old Caucasian male diagnosed with Crohn's (CD) at 14 years age (Montreal Classification A1L1L4B1p). He initially...
This is a case of 67-year-old female with chronic refractory gastro-cutaneous fistula secondary to multiple abdominal surgeries. The patient had partial gastrectomy following perforated gastric ulcer in 1992. She then underwent Roux-en-Y reconstruction 2004 and further revision 2014 resection her remnant subsequent complications. After surgery 2014, she developed that was successfully closed endoscopic suturing. However, two years later, an wall abscess found have recurrence the fistulous...
Introduction: Iron deficiency anemia (IDA) and diarrhea can be indicators of underlying celiac disease (CD) and/or inflammatory bowel (IBD). Studies have found that low socioeconomic status race impact healthcare delivery in IBD other chronic diseases. The aim our study was to determine if insurance impacts whether patients with IDA are evaluated appropriately. Methods: We identified 18 years older who were seen at the University Chicago Medicine (UCM) from Jan 1, 2006 Sept 20, 2017. used...