A5066285046- Neuroscience and Neuropharmacology Research
- Epilepsy research and treatment
- Receptor Mechanisms and Signaling
- Neurotransmitter Receptor Influence on Behavior
- Neuropeptides and Animal Physiology
- Ion channel regulation and function
- Diet and metabolism studies
- Neuroendocrine regulation and behavior
- Pharmacological Effects and Toxicity Studies
- Memory and Neural Mechanisms
- Regulation of Appetite and Obesity
- Anesthesia and Pain Management
- Stress Responses and Cortisol
- Pharmacological Receptor Mechanisms and Effects
- Hormonal and reproductive studies
- Neurological Disease Mechanisms and Treatments
- Pain Management and Opioid Use
- Pain Mechanisms and Treatments
- Hydrogen's biological and therapeutic effects
- Sexual function and dysfunction studies
- Antioxidant Activity and Oxidative Stress
- Nerve Injury and Rehabilitation
- Biochemical Analysis and Sensing Techniques
- Biochemical effects in animals
- Spine and Intervertebral Disc Pathology
Istanbul Yeni Yüzyıl University
2013-2024
Istanbul University
2001-2016
Local administration of insulin-like growth factor-I (IGF-I) has been shown to increase the rate axon regeneration in crush-injured and freeze-injured rat sciatic nerves. platelet-rich plasma (PRP) also have a measurable effect on facial nerve after transection model. The objective study was compare effects locally administered IGF-I PRP parameters Sciatic Function Index (SFI), sensory function (SF), count, myelin thickness/axon diameter ratio (G-ratio) model nerves.The right Wistar albino...
Food intake triggers convulsions in fasted mice and rats treated with antimuscarinic drugs, scopolamine or atropine. Bearing some similarities triggering factor manifestations of the seizures patients eating-evoked epilepsy, animals may provide insight into mechanism(s) this rare partially controlled form reflex epilepsy.
Primary objective: The present study was undertaken to evaluate whether enoant, which is rich in polyphenols, has any effect on electroencephalogram (EEG), oxidative stress and inflammation ischemia/reperfusion (I/R) injury.Methods: Ischemia induced by 2-hour occlusion of bilateral common carotid artery. Animals orally received enoant. Group 1 the ischemic control group. 2 treated with enoant 1.25 g kg−1 per day for 15 days after I/R. 3 same concentration as group before 4 sham operation EEG...
The purpose of the study was to compare neurotoxic effects intrathecally administered levobupivacaine, fentanyl and their mixture on rat spinal cord.In experiment, there were four groups with medication a control group. Rats injected 15μL saline or 0.0005μg/15μL, levobupivacaine 0.25%/15μL 0.0005μg+levobupivacaine for days. Hot plate test performed assess neurologic function after each injection at 5th, 30th 60th min. Five days last lumbal injection, cord sections between T5 T6 vertebral...
It has been shown that mice and rats treated with antimuscarinic drugs, scopolamine or atropine, after fasting for 48 h develop convulsions soon refeeding. The present study was performed to evaluate whether also being deprived of food 1-24 h. effect day-night on the development determined in 12-h animals. Mice were periods 1, 2, 3, 6, 9, 12, 18, 24, Animals fasted 12 during day night at 08:00 20:00 h, respectively. At time testing, animals intraperitoneal (i.p.) saline 3 mg/kg scopolamine....
Background: The purpose of the study was to compare neurotoxic effects intrathecally administered levobupivacaine, fentanyl and their mixture on rat spinal cord.Methods: In experiment, there were four groups with medication a control group.Rats injected 15 L saline or 0.0005 g/15 L, levobupivacaine 0.25%/15 g + for days.Hot plate test performed assess neurologic function after each injection at 5th, 30th 60th min.Five days last lumbal injection, cord sections between T5 T6 vertebral levels...
Free radicals and neutrophils are potent sources of ischemia-reperfusion injury (I/R) they can be limited by the use exogenous application some therapeutic agents. The objective this study was to compare effects cilostazol diltiazem hydrochloride in a rat hind limb model I/R injury. Methods: Skeletal muscles submitted 2 hours ischemia placing an aneurysm clip femoral artery reperfused after 1, 4 hours. Seventy-two Wistar-Albino rats were randomly divided into mainly four groups according...