A5065189599- Global Public Health Policies and Epidemiology
- Acute Myocardial Infarction Research
- Cardiovascular Health and Risk Factors
- Patient Satisfaction in Healthcare
- Health Systems, Economic Evaluations, Quality of Life
- Primary Care and Health Outcomes
- Healthcare professionals’ stress and burnout
- Healthcare Policy and Management
- Cardiac Health and Mental Health
- Nutritional Studies and Diet
- Diabetes, Cardiovascular Risks, and Lipoproteins
- COVID-19 and Mental Health
- Sepsis Diagnosis and Treatment
- Emergency and Acute Care Studies
- Chronic Disease Management Strategies
- Cardiovascular Disease and Adiposity
- Global Health Care Issues
- Geriatric Care and Nursing Homes
- Lipoproteins and Cardiovascular Health
- Health and Medical Research Impacts
- Climate Change and Health Impacts
- Health and Well-being Studies
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Health Sciences Research and Education
Mayo Clinic in Arizona
2018-2025
Mayo Clinic
2017-2025
Brigham and Women's Hospital
2014-2024
Mayo Clinic in Florida
2022-2023
Purdue University West Lafayette
2023
International Data Group (Sweden)
2022
Harvard University
2015-2021
National Institutes of Health
2020
University of Toronto
2003-2018
World Bank Group
2017-2018
Data from a comprehensive literature search of environmentally relevant physical-chemical properties for nine polybrominated diphenyl ethers (PBDE), ranging monobrominated congener to the fully brominated decabromodiphenyl ether, were evaluated and adjusted achieve both internal interhomologue consistency. These data then used in four model-based long-range transport potential (LRTP) assessment methods. The models TaPL3-2.10, ELPOS-1.1.1, Chemrange-2, Globo-POP-1.1 found yield comparable...
Risk profiles for premature coronary heart disease (CHD) are unclear.To examine baseline risk incident CHD in women by age at onset.A prospective cohort of US female health professionals participating the Women's Health Study was conducted; median follow-up 21.4 years. Participants included 28 024 aged 45 years or older without known cardiovascular disease. Baseline were obtained from April 30, 1993, to January 24, 1996, and analyses conducted October 1, 2017, 2020.More than 50 clinical,...
Sepsis is a burdensome condition worldwide in terms of morbidity, mortality and financial cost to health systems. A recent global task force report that was endorsed by 31 clinical societies defined sepsis as "life-threatening organ dysfunction caused dysregulated host response infection
Statins decrease levels of low-density lipoprotein (LDL) and triglycerides as well cardiovascular events but increase the risk for a diagnosis type 2 diabetes mellitus (T2DM). The factors associated with incident T2DM are incompletely characterized.To investigate association subclasses size novel insulin resistance (LPIR) score (a composite 6 measures) among individuals randomized to high-intensity statin or placebo.This secondary analysis JUPITER trial placebo-controlled clinical trial) was...
Type II diabetes (T2D) is preceded by prolonged insulin resistance and relative deficiency incompletely captured glucose metabolism parameters, high-density lipoprotein (HDL) cholesterol triglycerides.Whether (LPIR) score, a metabolomic marker, associated with incident improves risk reclassification over traditional markers on extended follow-up.Among 25,925 nondiabetic women aged 45 years or older, LPIR was measured nuclear magnetic resonance spectroscopy as weighted score of very low...
Background Patients with COVID-19 infection requiring in-hospital care are frequently managed by Internal Medicine hospitalists, comprised of physicians, nurse practitioners and physician assistants. There is sparse information on the psychological impact pandemic hospitalists.
Importance US rural vs nonrural populations have striking disparities in diabetes care. Whether rurality contributes to mortality is unknown. Objective To examine rates and trends based on county urbanization. Design, Setting, Participants In this observational, cross-sectional study, the Centers for Disease Control Prevention Wide-Ranging Online Data Epidemiologic Research database was searched from January 1, 1999, December 31, 2018, as a multiple cause underlying of death among residents...
Abstract Background Hospital‐at‐home (HaH) is a growing model of care that has been shown to improve patient outcomes, satisfaction, and cost‐effectiveness. However, selecting appropriate patients for HaH challenging, often requiring burdensome manual screening by clinicians. To facilitate enrollment, electronic health record (EHR) tools such as best practice advisories (BPAs) can be used alert providers potential candidates. Objective describe the development implementation BPA identifying...
Introduction Optimal hospital bed utilization requires innovative patient care models. We studied a novel hospitalist model utilizing telemedicine to facilitate collaboration with affiliated emergency departments (EDs) and support medical triage of ED patients high likelihood admission. Methods Telehospitalists based at tertiary facility collaborated four community EDs in the same healthcare network between January 1, 2022, April 30, 2023. supported clinicians decisions facilitated...
The rising incidence of noncommunicable diseases, combined with the costs mitigating climate change, sovereign debt and regional conflicts, is undermining global health security threatening progress towards achieving sustainable development goals United Nations. negative impact these polycrises disproportionately borne by low- middle-income countries, which have highest disease burden lowest health-care spending. Health digitalization emerging as a promising countermeasure, accelerated...
<sec> <title>BACKGROUND</title> High quality post-hospital care is crucial for positive patient outcomes following hospital discharge. Despite a preference home-based care, many patients are admitted to post-acute facilities. Our study explores the use of technology support transitioning from home. </sec> <title>OBJECTIVE</title> To develop patient-centered framework using design principles aiding in <title>METHODS</title> A vignette-based, mixed-method survey was conducted with 116 recently...
The molecular mechanisms that regulate adult neural precursor cell (NPC) survival, and thus maintain neurogenesis, are not well defined. Here, we investigate the role of p63, a p53 family member, in NPC function mice. Conditional ablation p63 NPCs or haploinsufficiency led to reduced numbers newborn neurons neurogenic zones hippocampus lateral ventricles olfactory bulb. These reductions were attributable enhanced apoptosis rescued by inhibition caspase activity, p53, apoptotic effector PUMA...
Statin use has increased substantially in North America and Europe, with resultant reductions cardiovascular mortality. However, little is known about statin lower-income countries. India of interest because its burden disease, the unique nature prescription drug market, growing globalization sales. We conducted an observational study using IMS Health data for period February 2006–January 2010. During period, monthly prescriptions from 45.8 to 84.1 per 1,000 patients coronary heart...
The molecular mechanisms that regulate survival of embryonic neural precursors are still relatively ill-defined. Here, we have asked whether the p53 family member p63 plays any role during this developmental window, focusing on cerebral cortex. We show genetic knockdown either in culture or telencephalon causes apoptosis cortical and newly born neurons, can be rescued by expression ΔNp63, but not TAp63 isoforms. This precursor is consequence deregulated activity, since both basal induced...