A5010009380- Thyroid Disorders and Treatments
- Diabetes and associated disorders
- Thyroid Cancer Diagnosis and Treatment
- Gut microbiota and health
- Digestive system and related health
- Pituitary Gland Disorders and Treatments
- Helicobacter pylori-related gastroenterology studies
- T-cell and B-cell Immunology
- Thyroid and Parathyroid Surgery
- Growth Hormone and Insulin-like Growth Factors
- Reproductive System and Pregnancy
- Celiac Disease Research and Management
- Vitamin D Research Studies
- Gastroesophageal reflux and treatments
- Atherosclerosis and Cardiovascular Diseases
- Salivary Gland Disorders and Functions
- Neutropenia and Cancer Infections
- Radiation Dose and Imaging
- Gastrointestinal motility and disorders
- Pregnancy and preeclampsia studies
- Urticaria and Related Conditions
- Ion Transport and Channel Regulation
- Diet, Metabolism, and Disease
- Potassium and Related Disorders
- COVID-19 Clinical Research Studies
Sapienza University of Rome
2017-2025
Policlinico Umberto I
2023
Ospedale Santa Maria Goretti
2023
University of L'Aquila
2022
Abstract Context The risk of recurrence papillary thyroid carcinoma smaller than 1 cm (microPTC) is low. Predictors disease persistence in microPTC are still unclear. Objective To compare the clinical and pathological characteristics microPTCs with macrocarcinomas (PTC > cm), identifying predictors biochemical structural incomplete response one year after initial treatment microPTC. Methods We included patients consecutively enrolled Italian Thyroid Cancer Observatory (NCT04031339),...
Background: An increased rate of recurrent miscarriage has been described in patients with autoimmune thyroid disease. However, there is a lack studies that assess the pregnancy loss (RPL) Hashimoto's thyroiditis (HT) isolated or concurrent non-endocrine disorders (NEAD). The objective study was to RPL HT accompanied diseases. Methods: This retrospective observational cohort systematic review NEAD an outpatient Endocrinology Unit at University Hospital. Among 3480 consecutively examined...
Despite the absorption of oral thyroxine (T4) occurs in small bowel, several patients with gastric disorders show an increased need for T4. In vitro evidence suggested that medium pH variations interfere T4 dissolution. This study was aimed at finding proof concept a direct relationship between minimal effective dose and actual juice pH.Among 311 consecutively thyroxine-treated patients, 61 bearing Hashimoto's thyroiditis (52 F/9 M; median age = 51 years) who complained persistent dyspepsia...
In recent years, the role of gastric and duodenal microbiota has acquired increasing importance in homeostasis host, although, to date, most evidence concern faecal microbiota. Indeed, gastric, are challenging study, due acid, bile, digestive enzymes, rapid transit time. Specifically, acid environment may influence their bacterial composition since barrier protects against orally ingested microorganisms leads inactivation before reaching intestine. The aim this study was assess a correlation...
Background: Thyroxine absorption takes place at the small intestine level and several disorders affecting this intestinal tract lead to thyroxine malabsorption. An increased need for has also been observed in gastric due variations drug dissolution and/or its ionization status. Ulcerative colitis (UC) is an inflammatory bowel disease that postulated as a potential cause of thyroxine, but there lack evidence on topic. This study aimed measuring requirement hypothyroid patients with UC....
Hashimoto’s thyroiditis (HT) may occur associated with celiac disease (CD). Regulatory B cells (Breg) subsets have been shown to play a significant role in autoimmune processes. Therefore, we characterized their distribution the peripheral blood obtained from 10 patients isolated HT, HT + CD, 9 and healthy donors (HD). Th17 were significantly increased bearing both while CD exhibited lower percentage of Th17, as compared donors. CD24 hi CD38 Breg higher HD (<mml:math...
Significant uncertainty exists about the diagnostic accuracy of ultrasonographic (US) features used to predict risk thyroid cancer in pediatric population. Moreover, there are no specific indications for nodule evaluation patients during transition age.
Softgel levothyroxine (LT4) preparation showed a better in vitro dissolution profile at increasing pH as compared to tablet LT4 preparation. Clinical studies suggested performance of softgel patients with gastric disorders but whether this finding is related juice variation vivo not known.Twenty-eight hypothyroid (24F/4M; median age=50 treated (median dose= 1.65 µg/kg/day) and stable thyroid stimulating hormone (TSH) values on target (<0.8-2.5> mU/l) have been shifted The dose has titrated...
Abstract Background Sellar/parasellar lesions have been studied in the adult and paediatric age range, but during transition their epidemiology, clinical manifestations, management treatment outcomes poorly investigated. Materials methods An Italian multicentre cohort study, which hospital records of patients with diagnosis sellar/parasellar young adulthood (15–25 years), were reviewed terms prevalence, hormonal features at diagnosis, where available. Both pituitary neuroendocrine tumours...
Abstract Background CD20 + T cells represent up to 5% of circulating lymphocytes. These have been shown produce higher levels IL-17A and IFN-γ than those − Some reports described the role in autoimmune disorders such as multiple sclerosis rheumatoid arthritis possibly due their ability these inflammatory cytokines. This study is aimed at describing behavior lymphocytes most frequent disorder, i.e., Hashimoto’s thyroiditis (HT), presenting isolated or associated further autoaggressive a frame...
Background Hypothyroidism is treated with daily levothyroxine (LT4). In recent years, soft gel caps of LT4 (LT4-C) have been commercialized, and their performance has optimized. Since guidelines recommend dose according to the tablet preparation efficacy, present study was undertaken obtain data about requirement, normalized per body weight, LT4-C. Methods Patients undergoing LT4-C after total thyroidectomy radioiodine treatment for differentiated thyroid carcinoma were selected. There no...
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)