A5082001651- Neuroendocrine Tumor Research Advances
- Lung Cancer Research Studies
- Neuroblastoma Research and Treatments
- Hormonal and reproductive studies
- Sperm and Testicular Function
- Testicular diseases and treatments
- Ovarian cancer diagnosis and treatment
- Sexual Differentiation and Disorders
- Thyroid Cancer Diagnosis and Treatment
- Pituitary Gland Disorders and Treatments
- Pancreatic and Hepatic Oncology Research
- Adrenal and Paraganglionic Tumors
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Hormonal Regulation and Hypertension
- Growth Hormone and Insulin-like Growth Factors
- Cancer, Lipids, and Metabolism
- Thyroid and Parathyroid Surgery
- Cervical Cancer and HPV Research
- Glycosylation and Glycoproteins Research
- Multiple and Secondary Primary Cancers
- Sex and Gender in Healthcare
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Urinary Bladder and Prostate Research
- Bone health and treatments
- Cancer Risks and Factors
Sapienza University of Rome
2018-2025
Azienda Ospedaliera Sant'Andrea
2022
Istituti di Ricovero e Cura a Carattere Scientifico
2022
Istituto Neurologico Mediterraneo
2022
Ospedale Santa Maria Goretti
2022
Cancer Institute (WIA)
2022
Policlinico Umberto I
2020-2021
Università Cattolica del Sacro Cuore
2016
University of Rome Tor Vergata
2012-2013
Universidade Nove de Julho
2000
Background/Objectives: HPV is the most common sexually transmitted infectious agent worldwide and adolescents are at high risk of contracting HPV. The aim our study was to find out how much know about virus its effects, obtain information on attitudes behaviors regarding vaccination close these gaps. Methods: As part ESPRIT project, 598 lower secondary (11–14 years) upper (14–19 school students from three Italian regions were surveyed between December 2023 March 2024 using a seven-question...
Cyclic GMP–phosphodiesterase type 5 (PDE5) inhibition has been shown to counteract maladaptive cardiac changes triggered by diabetes in some but not all studies. We performed a single-center, 20-week, double-blind, randomized, placebo-controlled trial (NCT01803828) assess sex differences remodeling after PDE5 patients with diabetic cardiomyopathy. A total of 122 men and women (45 80 years) long-duration (>3 well-controlled 2 mellitus (T2DM; HbA1c < 86 mmol/mol) were selected according...
Abstract Purpose Pancreatic neuroendocrine tumors (pNETs) are frequent in multiple endocrine neoplasia type 1 (MEN1) syndrome. They usually not surgically treated unless larger than to 2 cm or a growth rate &gt; 0.5 per year. Somatostatin analogues represent one of the main therapeutic options pNETs, but they have never been prospectively investigated MEN1-related pNETs. The aim this study was evaluate effectiveness lanreotide patients with pNETs &lt; cm. Methods MEN1 more maximal...
Testicular ultrasound (US) is routinely employed in the evaluation of reproductive and sexual function. However, its use for characteristics other than testicular volume hampered by a lack information on prognostic value findings, which to date have only been incorporated score proposed Lenz et al 1993.We sought explore whether US examination can predict quality spermatogenesis provide endocrine function.We retrospectively reviewed 6210 examinations, finally selecting examinations from 2230...
Well-differentiated lung neuroendocrine tumors (Lu-NET) are classified as typical (TC) and atypical (AC) carcinoids, based on mitotic counts necrosis. However, prognostic factors, other than tumor node metastasis (TNM) stage the histopathological diagnosis, still lacking. The current study is aimed to identify potential factors better stratify NET, thus, improving patients' treatment strategy follow-up.A multicentric retrospective study, including 300 Lung all surgically removed, from...
Klinefelter syndrome is the most common chromosomal disorder in males and cause of hypergonadotropic hypogonadism. We describe natural history testicular dysfunction patients with through integration clinical, hormonal, quantitative ultrasound data a life-course perspective.Prospective semilongitudinal study.We included 155 subjects 47,XXY karyotype (age range: 7 months-55 years) naïve to testosterone replacement therapy. Subjects were divided according pubertal stage age group (transition...
Background: Early diagnosis of medullary thyroid cancer (MTC) when basal calcitonin (CT) levels are <100 pg/ml remains a clinical challenge. The calcium stimulation test is unique tool for stimulating CT. However, standardized and sex-specific cutoff values lacking. Therefore, this study aimed to investigate whether the CT adequate diagnosing MTC in both sexes identify values. Methods: This was an individual patient data (IPD) meta-analysis. A literature search performed using Scopus,...
Introduction. Pheochromocytomas (PCCs), paragangliomas (PGLs), ganglioneuroblastomas (GNBs) and ganglioneuromas (GNs) are neuroendocrine neoplasms (NENs) sharing a common embryologic origin from neural crest cells. However, they rarely occur concurrently recurrently. We describe the case of 40-year-old woman with "composite PCC-GN" multiple NENs neuroblastic tumors. Case presentation. The patient was first referred to our department at age 15 years for paroxysmal hypertension, headache,...
Abstract Purpose The role of osteocalcin (OCN) in pubertal development, male hypogonadism, and the effect testosterone (Te) replacement therapy (TRT) remains unclear. We aimed to investigate total OCN (tOCN) concentrations patients with Klinefelter syndrome (KS), a model adult hypergonadotropic hypogonadism. Methods This retrospective longitudinal study investigated 254 KS (47,XXY) between 2007 2021 at an academic referral center, categorized as (1) prepubertal, (2) pubertal, (3) adults. All...