Irene Persano

ORCID: 0000-0003-2004-4644
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About
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Research Areas
  • Neuroendocrine Tumor Research Advances
  • Lung Cancer Research Studies
  • Neuroblastoma Research and Treatments
  • COVID-19 and healthcare impacts
  • Gestational Trophoblastic Disease Studies
  • Pancreatic and Hepatic Oncology Research
  • Infection Control and Ventilation
  • Ocular Oncology and Treatments
  • Advanced Breast Cancer Therapies
  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Palliative Care and End-of-Life Issues
  • Gyrotron and Vacuum Electronics Research
  • Chronic Disease Management Strategies
  • Emergency and Acute Care Studies
  • Advances in Oncology and Radiotherapy
  • Healthcare cost, quality, practices
  • Brain Metastases and Treatment
  • Vaccine Coverage and Hesitancy
  • Myasthenia Gravis and Thymoma

Ospedale San Luigi Gonzaga
2020-2024

Azienda Sanitaria Ospedaliera S.Croce e Carle Cuneo
2023

University of Turin
2020-2023

Gonzaga University
2022

<h3>Importance</h3> Data about the optimal timing for initiation of peptide receptor radionuclide therapy (PRRT) advanced, well-differentiated enteropancreatic neuroendocrine tumors are lacking. <h3>Objective</h3> To evaluate association upfront PRRT vs chemotherapy or targeted with progression-free survival (PFS) among patients advanced who experienced disease progression after treatment somatostatin analogues (SSAs). <h3>Design, Setting, and Participants</h3> This retrospective,...

10.1001/jamanetworkopen.2022.0290 article EN cc-by-nc-nd JAMA Network Open 2022-02-24

Background: The optimal treatment sequencing for advanced, well-differentiated pancreatic neuroendocrine tumors (pNETs) is unknown. We performed a multicenter, retrospective study to evaluate the best sequence in terms of progression-free survival first-line (PFS1) and second-line (PFS2), overall among patients with pNETs. Methods: This multicenter retrospectively analyzed prospectively collected data sporadic pNETs who received at least two consecutive therapeutic lines, evidence...

10.3390/jcm13072074 article EN Journal of Clinical Medicine 2024-04-03

Well-differentiated lung neuroendocrine tumors (Lu-NET) are classified as typical (TC) and atypical (AC) carcinoids, based on mitotic counts necrosis. However, prognostic factors, other than tumor node metastasis (TNM) stage the histopathological diagnosis, still lacking. The current study is aimed to identify potential factors better stratify NET, thus, improving patients' treatment strategy follow-up.A multicentric retrospective study, including 300 Lung all surgically removed, from...

10.1007/s12020-022-03015-w article EN cc-by Endocrine 2022-03-18

Neuroendocrine carcinomas (NECs) are poorly differentiated and highly aggressive epithelial neuroendocrine neoplasms. The most common primary site is the lung, but they may arise in every organ. Approximately 37% of extrapulmonary NECs (EP-NECs) occur gastroenteropancreatic (GEP) tract, followed by genitourinary (GU) system gynecological tract. As a result their rarity, there scant evidence to guide treatment recommendations, multidisciplinary approach essential for management such patients....

10.3390/jcm12247715 article EN Journal of Clinical Medicine 2023-12-15

Hospital admission (HA) in cancer history is a common, repeated and frequently unplanned event. The emergency departments (EDs) the oncological outpatient service (OOS) are ordinary way of entry. We studied reasons admission, pathways access discharge prognostic factors population admitted patients with cancer.The health records ward referral hospital 6-month period were retrieved analysed. characteristics those last 3 months life compared other group.Among 147 HA, 79.5% unplanned, 48.9%...

10.1136/spcare-2023-004574 article EN BMJ Supportive & Palliative Care 2023-09-13

Abstract Purpose Thyroid transcription factor‐1 (TTF‐1) assessed by immunohistochemistry (IHC) is a specific biomarker for lung adenocarcinoma, and commonly used to confirm the pulmonary origin of neuroendocrine tumours (NET). The majority available data suggest that TTF-1 favourable prognostic adenocarcinomas, whereas its role more conflicting NET. main aim this multicenter retrospective study was investigate potentially relevant associations between clinical pathological features...

10.1007/s12020-023-03542-0 article EN cc-by Endocrine 2023-09-30

PURPOSE: COVID-19 cancer patients (C19-CP) represent a population at high risk for mortality, whose clinical characteristics are still unknown in the second SARS-CoV-2 wave. The aim of this retrospective study was to compare epidemiology and presentation C19-CP referring emergency department (ED) our institution (San Luigi Gonzaga University Hospital, Orbassano, Turin, Italy), 3-week observation period first waves, starting from introduction corresponding national lockdowns. METHODS: We...

10.1200/op.21.00098 article EN JCO Oncology Practice 2021-07-06

Since SARS-CoV-2 infection rapidly spread around the world, Italy has quickly become one of most affected countries. Healthcare systems introduced strict control measures to ensure optimal care, especially in frail groups such as cancer patients (pts). This study investigated efficacy pre-procedure screening and whether COVID-19 influenced timely diagnosis therapy.Data oncological procedures pts with confirmed or suspected diagnosis, treated at Oncology Department coming from Emergency San...

10.37349/etat.2021.00058 article EN cc-by Exploration of Targeted Anti-tumor Therapy 2021-10-31

Safety data regarding BNT162b2 in cancer patients (CPs) are scarce. Herein we report the side effects (SEs), adverse events (AEs), and patient-reported outcomes (PROs) following administration CPs treated at San Luigi Gonzaga University Hospital. All who agreed to participate our vaccination campaign received were included descriptive analysis. An anonymous questionnaire investigating occurrence of SEs/AEs PROs was administered study population 21 days after first dose. Pearson's chi-squared...

10.3390/biomedicines11010165 article EN cc-by Biomedicines 2023-01-09

Abstract Purpose Well-differentiated lung neuroendocrine tumors (Lu-NET) are classified as typical (TC) and atypical (AC) carcinoids, based on mitotic counts necrosis. However, prognostic factors, other than tumor node metastasis (TNM) stage the histopathological diagnosis, still lacking. The current study is aimed to identify potential factors better stratify NET, thus, improving patients’ treatment strategy follow-up. Methods A multicentric retrospective study, including 300 Lung all...

10.21203/rs.3.rs-1193325/v1 preprint EN cc-by Research Square (Research Square) 2022-01-05

Background: Glucagonoma is a rare functional pancreatic neuroendocrine tumor. Necrolytic migratory erythema (NME) paraneoplastic manifestation of glucagonoma and often the first presenting symptom. The misdiagnosis this entity can affect patient’s quality life his expectancy. Case Presentation: We report case 48-year-old man with pruritic scaly rash, ulcerated skin lesions, periorbital edema, who was diagnosed treated for atopic eczema 7-year period. Despite treatment, dermatitis general...

10.24911/ejmcr/173-1606402831 article EN European Journal of Medical Case Reports 2021-01-01
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