- Lung Cancer Treatments and Mutations
- Cancer Immunotherapy and Biomarkers
- Lung Cancer Research Studies
- Neuroendocrine Tumor Research Advances
- COVID-19 and healthcare impacts
- Lung Cancer Diagnosis and Treatment
- Cancer, Lipids, and Metabolism
- Prostate Cancer Treatment and Research
- Hormonal and reproductive studies
- Medical Imaging Techniques and Applications
- Infection Control and Ventilation
- Pancreatic and Hepatic Oncology Research
- Metastasis and carcinoma case studies
- Brain Metastases and Treatment
- Medical Imaging and Pathology Studies
- Colorectal Cancer Treatments and Studies
- Mycobacterium research and diagnosis
- Economic and Financial Impacts of Cancer
- Cancer Cells and Metastasis
- Cancer therapeutics and mechanisms
- Cancer Diagnosis and Treatment
- HER2/EGFR in Cancer Research
- COVID-19 Clinical Research Studies
University of Turin
2019-2023
Ospedale San Luigi Gonzaga
2019-2022
PURPOSE: COVID-19 cancer patients (C19-CP) represent a population at high risk for mortality, whose clinical characteristics are still unknown in the second SARS-CoV-2 wave. The aim of this retrospective study was to compare epidemiology and presentation C19-CP referring emergency department (ED) our institution (San Luigi Gonzaga University Hospital, Orbassano, Turin, Italy), 3-week observation period first waves, starting from introduction corresponding national lockdowns. METHODS: We...
Personalized treatment based on driver molecular alterations, such as ALK rearrangement, has revolutionized the therapeutic management of advanced oncogene addicted NSCLC patients. Multiple effective tyrosine kinase inhibitors (TKIs), with amelioration activity at central nervous system level, are now available, leading to substantial prognosis improvement. The exposure TKIs triggers resistance mechanisms and sequential administration other chemotherapy is, for most part, not targeted. In...
Background: Lung cancer (LC) tissue for immunological characterization is often scarce. We explored and compared T cell characteristics between broncho-alveolar lavage from tumor affected (t-BAL) contralateral lung (cl-BAL), with matched peripheral blood (PB). Methods: BAL PB were collected during bronchoscopy diagnostic and/or therapeutic purposes in patients monolateral primary lesion. Results: Of 33 undergoing sampling, 21 had histologically-confirmed LC. Most cases locally-advanced or...