A5053405176- Lung Cancer Diagnosis and Treatment
- Tracheal and airway disorders
- Medical Imaging and Pathology Studies
- Lung Cancer Treatments and Mutations
- Esophageal and GI Pathology
- Pleural and Pulmonary Diseases
- Airway Management and Intubation Techniques
- Salivary Gland Tumors Diagnosis and Treatment
- Esophageal Cancer Research and Treatment
- Tuberculosis Research and Epidemiology
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Advanced Radiotherapy Techniques
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Surgical Simulation and Training
- Dysphagia Assessment and Management
- Pneumocystis jirovecii pneumonia detection and treatment
- Tumors and Oncological Cases
- Radiomics and Machine Learning in Medical Imaging
- Oral and Maxillofacial Pathology
- Myasthenia Gravis and Thymoma
- Vascular Anomalies and Treatments
- Peripheral Nerve Disorders
- Head and Neck Surgical Oncology
- Inhalation and Respiratory Drug Delivery
- Pneumonia and Respiratory Infections
Université de Rouen Normandie
2015-2024
Centre Hospitalier Universitaire de Rouen
2007-2024
Hôpital Charles-Nicolle
2007-2023
Intergroupe Francophone de Cancérologie Thoracique
2022
Laboratoire d'Informatique, du Traitement de l'Information et des Systèmes
2013-2020
Inserm
2013-2016
Hôpital Charles-Nicolle
2006
The aim of the present study was to assess fibred confocal fluorescence microscopy (FCFM) as a tool for imaging alveolar respiratory system in vivo during bronchoscopy. A 488-nm excitation wavelength FCFM device used 41 healthy subjects including 17 active smokers. After topical anaesthesia, 1.4-mm miniprobe introduced into bronchoscope working channel and advanced distally alveoli. Morphometric cellular analyses were performed on selected frames harbouring minimal compression effect. In...
<b><i>Background:</i></b> Therapeutic bronchoscopy (TB) is an accepted strategy for the symptomatic management of central airway malignant obstruction. Stent insertion recommended in case extrinsic compression, but its value preventing re-obstruction after endobronchial treatment without compression unknown. <b><i>Objective:</i></b> Silicone stent Placement Obstruction due to non-small cell lung Cancer (SPOC) first randomized controlled trial...
Abstract Background and Objective EpiGETIF is a web‐based, multicentre clinical database created in 2019 aiming for prospective collection of data regarding therapeutic rigid bronchoscopy (TB) malignant central airway obstruction (MCAO). Methods Patients were enrolled into the registry from January to November 2022. Data prospectively entered through web‐interface, using standardized definitions each item. The objective this first extraction was describe population techniques used among...
Abstract Background and objective Treatment optimization of non‐squamous non‐small‐cell lung cancers ( nonS q‐ NSCLC ) relies on the molecular analysis tumour. We aimed to assess predictive factors feasibility MAF from samples peripheral obtained by radial endobronchial ultrasound bronchoscopy (r‐ EBUS 1.5 mm microbiopsy forceps. Methods reviewed data consecutive nodules sampled with r‐ between J anuary 2012 uly 2014 at a single F rench U niversity H ospital. were systematically analysed for...
Background: Ultrasonography is widely used in critical care practice. The status of related studies remains unclear. purpose this study to analyze current literature investigating the use ultrasound units by using bibliometric analysis. Methods: Science Citation Index Expanded (SCI-E) database was for data retrieval. search formula retrieval “ultrasound” OR “ultrasonography” AND “intensive unit” “critical care” care”. software package R results. Information literatures were analyzed....
Solitary pulmonary nodules (SPN) have become increasingly prevalent and diagnostic management remains challenging. We demonstrate a novel technique in which probe-based confocal endomicroscopy (pCLE) could be performed to microimage SPN vivo real-time. Two wavelengths (488 660 nm with methylene blue (MB)) were used for elastin network cellular imaging, respectively using pCLE conjunction r-EBUS virtual navigation. In the first case, 1-mm Alveoflex® was image metastatic melanoma...
Abstract: Minimally invasive sublobar anatomical resection is becoming more and popular to manage early lung lesions. Robotic-assisted thoracic surgery (RATS) unique in comparison with other minimally techniques. Indeed, RATS able better integrate multiple streams of information including advanced imaging techniques, an immersive experience at the level robotic console. Our aim was describe three-dimensional (3D) throughout surgical procedure from preoperative planning intraoperative...
Background Malignant solitary pulmonary nodules (SPN) have become more prevalent, with upper lobes predilection. Probe-based confocal laser endomicroscopy (pCLE) provides in-vivo imaging of SPN. However, the stiffness 1mm probe (AlveoFlex) causes difficult accessibility to lobes. A thinner 600μm designed for bile duct exploration (CholangioFlex) has potential reach Objectives To examine malignant SPNs in all segments lungs using either 0.6mm or 1.4 mm and assess quality inter observer...
Minimally invasive surgery of pulmonary nodules allows suboptimal palpation the lung compared to open thoracotomy.The objective this study was assess endoscopic pleural dye marking using radial endobronchial ultrasound (r-EBUS) and virtual bronchoscopy localize small peripheral immediately before minimally resection.The procedure performed without fluoroscopy, under general anesthesia in operating room surgery. Then, 1 mL methylene blue (0.5%) instilled into guide sheath, wedged subpleural...
Endobronchial ultrasound-guided (EBUS) transbronchial needle aspiration (TBNA) has significantly improved the diagnostic workup for intrathoracic lymphadenopathies. More recently, EBUS intranodal forceps biopsy (IFB) been developed in an attempt to maximize yield by providing additional tissue. In this study, we aimed assess improvement of with EBUS-TBNA combined EBUS-IFB, compared alone.Consecutive patients who had 19-G and EBUS-IFB from August 30, 2018, September 28, 2021, were included....
Various advanced bronchoscopy methods have been developed to reach peripheral lung lesions (PLL). In a large cohort, we aimed assess standardized procedure of first-line radial-endobronchial ultrasound (r-EBUS) and virtual planner for the diagnosis cancer.This retrospective, single center study included patients who had r-EBUS-guided PLL between 2008 2019. Cases without final cancer or follow-up were excluded.Between 2019, 2735 r-EBUS procedure, among whom 1627 in present study. Over 12-year...
With the use of low-dose CT for early screening lung cancer, more and cancers are found. At same time, patients with small nodules have also increased, it is a great challenge surgeons to resect pulmonary volume, deep position no solid components under video-assisted thoracoscopic surgery. Many studies reported preoperative intraoperative methods localizing before minimally invasive resection. Methods localization include CT-guided hook-wire positioning, coil or dye injection radionuclide...
This two-step study evaluated the cost-effectiveness of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) for presurgery staging non-small cell lung cancer (NSCLC) in France (EVIEPEB; ClinicalTrial.gov identifier NCT00960271). Step 1 consisted a high-benchmark EBUS-TBNA–training program participating hospital centers. 2 was prospective, national, multicenter on patients with confirmed or suspected NSCLC and an indication mediastinal at least one lymph node > cm...
Patients undergoing flexible bronchoscopy under local anesthesia usually experience anxiety before and during the procedure. Different non-pharmacological techniques, including music hypnosis, are used to distract patients' attention, reduce anxiety. The new technique "virtual reality hypnosis (VRH)", defined as a hypnotic induction suggestion delivered by personalized virtual software, can generate simulation of lifelike environment. No study has described use VRH bronchoscopy. objective is...
Abstract Background and Objective Little is known about malignant central airway obstruction (MCAO) complicating the metastatic spread of non‐bronchogenic solid cancers (NBC) their bronchoscopic management. This study aimed to describe epidemiology this population determine prognostic factors before therapeutic bronchoscopy (TB). Methods In multicenter using EpiGETIF registry, we analysed patients treated with TB for MCAO caused by NBC between January 2019 December 2022. Results From a...