Hanène Djeghim

ORCID: 0000-0001-7913-6346
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About
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Research Areas
  • Essential Oils and Antimicrobial Activity
  • Coconut Research and Applications
  • Phytochemicals and Antioxidant Activities
  • Natural product bioactivities and synthesis
  • Brucella: diagnosis, epidemiology, treatment
  • Phytochemical compounds biological activities
  • Phytochemistry and Biological Activities
  • Bee Products Chemical Analysis
  • Listeria monocytogenes in Food Safety
  • Fatty Acid Research and Health
  • Peanut Plant Research Studies
  • Microbial infections and disease research
  • Herpesvirus Infections and Treatments
  • Mycotoxins in Agriculture and Food
  • Agricultural pest management studies
  • Bioactive natural compounds
  • Parasitic Infections and Diagnostics
  • Food composition and properties
  • Toxoplasma gondii Research Studies
  • Advanced Chemical Sensor Technologies
  • Pharmacological Effects of Medicinal Plants
  • Morinda citrifolia extract uses
  • Veterinary medicine and infectious diseases
  • Tea Polyphenols and Effects
  • Plant biochemistry and biosynthesis

University Frères Mentouri Constantine 1
2018-2025

Biotechnology Research Center
2021-2025

National Center for Biotechnology
2021

Ammodaucus leucotrichus exhibits promising pharmacological activity, hinting at anti-inflammatory and anti-arthritic effects. This study investigated seed extracts from using methanol n-hexane, focusing on properties. The extract outperformed the n-hexane diclofenac, a reference drug, in trypsin inhibition (85% vs. 30% 64.67% 125 μg/mL). For inhibition, IC50 values were 82.97 μg/mL (methanol), 202.70 (n-hexane), 97.04 (diclofenac). Additionally, surpassed diclofenac BSA (bovine serum...

10.3390/ph17030385 article EN cc-by Pharmaceuticals 2024-03-18

Plant-derived compounds have recently been gaining popularity as skincare factors due to their ability absorb ultraviolet radiations and anti-inflammatory, antioxidant properties. In this light, work aimed evaluate in vitro the pharmacological activities of butanolic extract prepared from aerial parts

10.3390/foods10081937 article EN cc-by Foods 2021-08-20

This study investigated the effects of genetic diversity in allergenicity peanut and assessed allergenic capacity six Arachis hypogaea accessions using a Balb/c mouse model. It also explored potential cross-reactivities between Ara h 3 (peanut allergen) Gly m (soybean computational tools. Female mice were injected with protein extracts alum. Serum-specific antibodies (IgE, IgGt, IgG1, IgG2a) measured ELISA, allergic profiles examined via western blot. Structural homology, B cell epitopes,...

10.1016/j.jprot.2024.105264 article EN cc-by-nc Journal of Proteomics 2024-07-22

Introduction Peanut oil is valued for its mild flavor, rich phytochemical content, therapeutic potential, and associated health benefits. This study aims to analyze the chemical composition, antioxidant properties, anti-Alzheimer’s potential of Algerian peanut using both experimental computational approaches. The goal evaluate suitability pharmaceutical applications, particularly antioxidant, anti-Alzheimer, anticancer properties. Methods composition was determined Gas Chromatography-Mass...

10.3389/fchem.2024.1487084 article EN cc-by Frontiers in Chemistry 2024-10-24

Abstract Acetylcholinesterase (AChE) is currently the most favorable target for symptomatic treatment and reduction of Alzheimer's disease (AD). In order to identify new potent inhibitors this enzyme, we describe herein a structure‐based virtual screening (SBVS) using Institut Curie‐CNRS chemical library (ICCL), which contained at date 14307 compounds. The strategy undertaken in work consisted use several docking programs SBVS calculations followed by application consensus method (vSDC)...

10.1002/minf.201800118 article EN Molecular Informatics 2019-02-06

<p>Beta-glucan, such as barley-derived beta-glucan (BBG), are homopolysaccharides that have attracted attention by their nutritional and therapeutic properties. The aim of this study was to evaluate the antioxidant power BBG extracted from local Algerian variety barley (SAIDA 183), its acetylcholinesterase, alpha glucosidase inhibitory activity well prebiotic potential fermentation with lactic acid bacteria isolated camel’s milk, namely <em>lactococcuslactisssplactis</em>...

10.5138/09750185.2229 article EN International Journal of Phytomedicine 2018-04-30

A previously undescribed triterpenoid saponin, 3-O-[α-l-rhamnopyranosyl-(1→2)-{β-d-glucopyranosyl-(1→6)-}β-d-galactopyranosyl-(1→2)-β-d-glucuronopyranosyl]-sophoradiol (1), in addition to twenty-nine known constituents (2-30) were isolated from the aerial parts of Genista numidica Spach. Structures elucidation was performed by comprehensive 1D- and 2D-NMR analyses HRESIMS. The extracts, fractions compounds evaluated for their antibacterial, antioxidant tyrosinase inhibitory activities....

10.1080/14786419.2018.1437425 article EN Natural Product Research 2018-02-15

This study was designed to evaluate the tyrosinase inhibitory effect, in vitro, vivo, and silico toxicity of fractions isolated from A. numidica de Lannoy needles. The cytotoxicity extracts examined against Artemia salina larvae, while these tested by acute oral mice; administration a dose 2000 mg/kg b.w leaves extracts. blood samples were collected eye orbital sinus for further analysis biochemical parameters. absorption, distribution, metabolism, elimination, (ADMET) properties identified...

10.3390/plants11182389 article EN cc-by Plants 2022-09-14

Background: Respiratory viral diseases, including the bovine parainfluenza 3 virus, cause significant economic losses in ruminants. There is no available data regarding epidemiological situation of this virus Algeria. Objectives: The present study aims to determine seroprevalence and associated risk factors (BPI3V) sheep two different climatic regions Methods: A total 108 serum samples were collected from at ages tested for antibodies against BPI3V using an indirect enzyme-linked...

10.32598/ijvm.18.2.1005387 article EN cc-by Iranian Journal of Veterinary Medicine 2024-04-01

This study investigated the prevalence of mycotoxin Ochratoxin A in poultry feed samples from Eastern Algeria, an important production region. A, produced by Aspergillus and Penicillium fungi, can contaminate feed, leading to toxicity issues for human beings consuming contaminated products. Analysis 42 using Enzyme-Linked Immunosorbent Assay (ELISA), found 62% contained detectable ochratoxin levels exceeding concentration 1.50 ng g−1, varying between 2.23 g−1 3.23 with average 2.59 g−1....

10.1080/00207233.2024.2369448 article EN International Journal of Environmental Studies 2024-06-19

ABSTRACTABSTRACTThe present study aimed to assess the occurrence of aflatoxins in foodstuffs most consumed by population Algeria. To determine aflatoxin B1 (AFB1) levels coffee samples marketed Constantine province (Algeria), 43 green and roasted were purchased from local markets shops. The concentration range AFB1 investigated a highly sensitive microtitre plate Enzyme-Linked Immunosorbent Assay (ELISA) method. detection quantification limits 0.2ng g−1 0.5ng g−1, respectively. results...

10.1080/00207233.2023.2181595 article EN International Journal of Environmental Studies 2023-02-23

Background. The peanut is one of the most important oil crops suitable for cultivation in tropical areas world. Despite its agronomic importance, few studies have been carried out to assess morphogenetic diversity Arachis hypogaea L., especially East African countries. major interest this morphologic study lies potential species provide useful genes improvement cultivated peanuts. To date, no has performed Algeria characterize local varieties. Materials and methods . Thirty accessions were...

10.30901/2227-8834-2021-3-111-124 article EN cc-by PROCEEDINGS ON APPLIED BOTANY GENETICS AND BREEDING 2021-10-09
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