Jinglun Shen

ORCID: 0000-0001-7937-6171
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About
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Research Areas
  • Infective Endocarditis Diagnosis and Management
  • Cardiac Valve Diseases and Treatments
  • Venous Thromboembolism Diagnosis and Management
  • Atrial Fibrillation Management and Outcomes
  • Aortic Disease and Treatment Approaches
  • Cardiac Structural Anomalies and Repair
  • Transplantation: Methods and Outcomes
  • Cardiovascular Function and Risk Factors
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cardiac Arrhythmias and Treatments
  • Coronary Interventions and Diagnostics

Beijing Anzhen Hospital
2019-2024

Capital Medical University
2019-2024

Background Mechanical heart valve replacement (MHVR) is an effective method for the treatment of severe disease; however, it subjects patient to lifelong warfarin therapy after MHVR with attendant risk bleeding and thrombosis. Whether internet-based management reduces complications improves quality life remains unknown. Objective This study aimed compare effects conventional approach in patients who received order provide evidence regarding alternative strategies long-term anticoagulation....

10.2196/29529 article EN cc-by Journal of Medical Internet Research 2021-07-06

Introduction Warfarin is an effective anticoagulant and the only oral available for patients with mechanical heart valves. The prothrombin time associated international normalised ratio (INR) are routinely tested to monitor response anticoagulation therapy in patients. Patients who undergo valve replacement need lifelong therapy, their INR regularly measured adjust strength dose of drugs. Appropriate warfarin management can reduce patient complications, such as bleeding thrombosis, improve...

10.1136/bmjopen-2019-032949 article EN cc-by-nc BMJ Open 2019-12-01

Background: Due to the influence of anatomical structure, replacing bicuspid valve using transcatheter aortic replacement (TAVR) would increase risk perivalvular leakage and conduction block, affecting hemodynamic effect interventional valve. In this study, for tricuspid valves, we implemented different selection strategies explore safety effectiveness TAVR in treatment stenosis with “down-size” valves VenusA-valve system. Methods: The operation was performed via transfemoral approach....

10.21037/jtd-23-1885 article EN Journal of Thoracic Disease 2024-01-01

Prior to the approval of Sapien valve in 2020, there were no commercially available short-frame valves for transapical mitral valve-in-valve (MVIV) implantation. In January 2019, we first attempted reverse mounted J-valve MVIV implantation with good clinical results. The present study aimed explore safety and effectiveness reversely on delivery system.Patients who underwent using analyzed from 2019 December 2020 a 1-year follow-up. Before procedure, computed tomography (CT) angiography data...

10.21037/atm-21-6513 article EN Annals of Translational Medicine 2022-01-01

Background: Patients with tricuspid bioprosthetic structural valve degeneration (SVD) often present right ventricular enlargement and severe dysfunction, which cause a higher risk for redo cardiac surgery. In 2019, our center innovated using the J-valve system valve-in-valve (ViV) implantation to treat SVD. The purpose of this study was summarize clinical effect after 1-year follow-up. Case Description: From April 2019 October two cases dysfunction were treated system. Both patients male,...

10.21037/jtd-23-1961 article EN Journal of Thoracic Disease 2024-02-01

In recent years, transcatheter aortic valve implantation (TAVI) has become a widely used treatment for low-risk elderly patients. As an alternative to TAVI via the femoral artery, transapical (TA-TAVI) is better surgical choice patients with severe vascular diseases. The J-Valve assists doctors in completing easily using its positioning locator device, which prevents self-leaflet from approaching sinus wall. This function acts as coronary artery protection avoid occlusion. However, clinical...

10.1186/s13019-024-03012-2 article EN cc-by-nc-nd Journal of Cardiothoracic Surgery 2024-08-28

Background: Coronary obstruction (CO) is a fatal complication in transcatheter aortic valve replacement (TAVR). However, data on the outcomes and details of coronary protection (CP) use TAVR are limited. Methods: We retrospectively analyzed patients who had undergone CP during at our tertiary cardiac center from March 2017 to January 2024. was achieved by an undeployed balloon or stent positioned within artery, which releases CO occurrence. Patients' computed tomography (CT) evaluation...

10.31083/j.rcm2511407 article EN cc-by Reviews in Cardiovascular Medicine 2024-11-20

Valve-in-valve transcatheter mitral valve replacement (ViV-TMVR) is a minimally invasive option for patients with bioprosthetic failure. Since January 2019, our center has been using new innovative option, J-Valve, to treat failure who were at high risk open heart surgery. The aim of this study explore the effectiveness and safety J-Valve report results from four-year follow-up period application valve.Patients underwent ViV-TMVR procedure between 2019 September 2022 in included study....

10.3389/fcvm.2023.1137663 article EN cc-by Frontiers in Cardiovascular Medicine 2023-06-12

<sec> <title>BACKGROUND</title> Mechanical heart valve replacement (MHVR) is an effective method for the treatment of severe disease; however, it subjects patient to lifelong warfarin therapy after MHVR with attendant risk bleeding and thrombosis. Whether internet-based management reduces complications improves quality life remains unknown. </sec> <title>OBJECTIVE</title> This study aimed compare effects conventional approach in patients who received order provide evidence regarding...

10.2196/preprints.29529 preprint EN 2021-04-11

Background: Porcine valves are used for mitral valve replacement, but the limited long-term durability has restricted application in younger patients. Degenerated porcine were explanted to analyze failure modes and damage characteristics.Methods: Twelve via secondary replacement surgery. Microcomputed tomography scanning, morphological pathological examinations performed classify cusp tears, calcification, pannus formation. The causes of deterioration subsequently analyzed.Results: mean age...

10.21037/jtd-20-3578 article EN Journal of Thoracic Disease 2021-05-01
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