A5038446892- Systemic Lupus Erythematosus Research
- Pregnancy and Medication Impact
- Metallurgical Processes and Thermodynamics
- Health Policy Implementation Science
- Systemic Sclerosis and Related Diseases
- Renal Diseases and Glomerulopathies
- Scheduling and Optimization Algorithms
- Primary Care and Health Outcomes
- Fault Detection and Control Systems
- Pharmacological Effects of Natural Compounds
- Heparin-Induced Thrombocytopenia and Thrombosis
- Atherosclerosis and Cardiovascular Diseases
- Genetic diversity and population structure
- Clinical practice guidelines implementation
- Liver Diseases and Immunity
- Mental Health and Patient Involvement
- Platelet Disorders and Treatments
- Innovations in Concrete and Construction Materials
- Diverse Scientific Research Studies
- Manufacturing Process and Optimization
- Modeling, Simulation, and Optimization
- Mineral Processing and Grinding
- Pharmaceutical studies and practices
- Gout, Hyperuricemia, Uric Acid
- Genetic and phenotypic traits in livestock
European League Against Rheumatism
2019-2024
Sanatorium Kilchberg
2024
RINA Consulting - Centro Sviluppo Materiali S.p.A. (Italy)
2000-2022
The objective was to develop evidence-based recommendations for the management of antiphospholipid syndrome (APS) in adults. Based on evidence from a systematic literature review and expert opinion, overarching principles were formulated voted. High-risk antibody (aPL) profile is associated with greater risk thrombotic obstetric APS. Risk modification includes screening cardiovascular venous thrombosis factors, patient education about treatment adherence, lifestyle counselling. Low-dose...
Objective To update the 2012 EULAR/ERA–EDTA recommendations for management of lupus nephritis (LN). Methods Following EULAR standardised operating procedures, a systematic literature review was performed. Members multidisciplinary Task Force voted independently on their level agreeement with formed statements. Results The changes include treatment targets, use glucocorticoids and calcineurin inhibitors (CNIs) end-stage kidney disease (ESKD). target therapy is complete response (proteinuria...
Objective To develop recommendations for cardiovascular risk (CVR) management in gout, vasculitis, systemic sclerosis (SSc), myositis, mixed connective tissue disease (MCTD), Sjögren’s syndrome (SS), lupus erythematosus (SLE) and antiphospholipid (APS). Methods Following European League against Rheumatism (EULAR) standardised procedures, a multidisciplinary task force formulated CVR prediction based on systematic literature reviews expert opinion. Results Four overarching principles...
<h3>Background:</h3> Counselling patients with rheumatic and musculoskeletal diseases (RMD) in the phase of reproduction, pregnancy lactation is a challenging task. In women, potential risk drug therapy needs to be weighed against untreated maternal RMD associated risks for mother child. men, safety antirheumatic drugs regard fertility pregnancy/offspring outcomes considered. The first EULAR points consider (PtC) use before pregnancy, during published 2016 have been widely used [1]....
A clinical guideline is a document with the aim of guiding decisions based on evidence regarding diagnosis, management and treatment in specific areas healthcare. Specific to rheumatic musculoskeletal diseases (RMDs), adherence guidelines recommendations impacts outcomes people these diseases. However, currently, implementation less than optimal rheumatology. The WHO has described evidence-based as one greatest challenges facing global health community identified importance scaling up...
Goat mtDNA haplogroup A is a poorly resolved lineage absorbing most of the overall diversity and found in locations as distant Eastern Asia Southern Africa. Its phylogenetic dissection would cast light on an important portion spread goat breeding. The aims this work were 1) to provide operational definition meaningful units within A, 2) investigate mechanisms underlying maintenance by considering modes selection operated breeders 3) identify peculiarities Sardinian types. We sequenced D-loop...
The steel industry is an important consumer of electrical energy having a significant impact on the electricity network and accounting to part production costs. Thus, there opportunity closer cooperation between grid operators improve power consumption prediction actively contribute secure operation. This paper aims describe overall dynamical approach for demand monitoring timely reactions situation, avoid non flexible equipment disconnection, financial fines when deviating from contingent...
A multi-agent system for the steel production is presented. It re-allocates off-spec products to existing alternative orders. The consists of three main Industry 4.0 components: agents, service-oriented architecture (SOA) and a semantic modelling process chain. Using economic principles like virtual marketplaces, solution reallocation reached by means auctions, where product agents act as sellers order bidders. price defines key matching between product. To incorporate postprocessing,...
<h3>Objectives</h3> To develop recommendations for family planning, assisted reproduction, pregnancy, and menopause in women with SLE and/or APS. <h3>Methods</h3> Research questions were compiled using a modified Delphi technique. A systematic PubMed search was performed an array of index terms. <h3>Results</h3> The preliminary set are presented. APS patients planning pregnancy should be counseled managed after risk stratification by taking into consideration disease activity (active/flaring...
<h3>Background</h3> Systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) have a high disease burden which cannot be sufficiently alleviated with pharmacological treatment alone. In summer 2023 EULAR recommendations for non-pharmacological management of SLE SSc were published https://doi.org/10.1136/ard-2023-224416. Dissemination implementation the into daily clinical practice is crucial due to impact on patients QoL holistic these diseases. <h3>Methods</h3> We first aim at raising...
<h3>Background:</h3> At EULAR 2023, the Lupus100 initiative was launched to address issue of unreliable online sources by ensuring 95% European lupus patients can access high-quality information in their native languages. This made possible thanks effective collaboration between and doctors who worked together create already 13 different language versions, available online. Reflecting on first year since Lupus100's launch provide valuable insights into patient engagement dissemination....
<h3>Background:</h3> In the absence of strategic direction, patient groups struggle to deliver results that meet their ambitions. Projects selection based on short term considerations or association funding combined with changing priorities prevent more significant projects implementation. <h3>Objectives:</h3> To share Lupus Europe experience how a simple plan helped achieve long goals and mobilise resources. <h3>Methods:</h3> Back in 2011, was small organisation, less than 30k€ annual...
<h3>Background</h3> The Patient – Doctor communication gap is often discussed, and one of the obstacles pointed by patients doctors alike in fruitful co-working optimal treatments. Recognizing difference between approach when confronted to a lupus flare critical bridge this increase effectiveness jointly agreed treatment plans. <h3>Objectives</h3> Identify potential discrepancies patient discussion starting points facing flare. Are they "talking same thing?", "do have similar concerns their...
In recent years, the steel industry has significantly raised its demands regarding product quality, optimization of production cost, environmental issues and lead-time. The demand for improved production performance in turn increased on information systems, particular highlighting need for factory- company-wide collaboration exchange. heterogeneity in structure, technology architecture systems deployed manufacturing plants presents further challenges to design implementation a...
Background: Up to 40% of systemic lupus erythematosus (SLE) patients develop kidney disease, which represents a major cause morbidity. Objectives: To update the 2012 EULAR/ERA-EDTA recommendations for management nephritis (LN). Methods: We followed EULAR standardised operating procedures publication treatment recommendations. Delphi-based methodology led 15 questions systematic literature review (SLR), was undertaken by three fellows. Results: The changes include targets, use glucocorticoids...
The Control In Steel project, a cooperation of four research institutes, revisited projects the last 20 years focusing on automation and control solutions applied to downstream steel production route. During this investigation we found hints those solutions, which were beneficial for specific problems. For our analysis, 46 systematically reviewed. Taxonomies problem space, solution barriers issues impact developed each project categorized along these taxonometrical dimensions. As result,...
<h3>Background</h3> Despite significant improvements in diagnosis delay and treatment strategies, the burden of Systemic Lupus Erythematosus (SLE) remains high. <h3>Objectives</h3> The objective study was to assess association between delay, disease activity on daily life (BoDL) a large sample European patients with SLE. <h3>Methods</h3> In May 2020, Europe, umbrella patient for SLE, conducted multilingual anonymous online cross-sectional individuals self-reported physician's SLE living...
<h3>Background</h3> Access to quality disease information is one of the cornerstones therapeutic education and critical help doctor-patient dialog adherence treatment. Lupus patients doctors alike lack time in consultation address many questions have. As a result, often rely on poor or unverified from web. For non-English speakers, language barrier adding yet another obstacle education. <h3>Objectives</h3> To provide access doctor verified SLE on-line, mother 95%+ European population so that...
ABSTRACT Objective Despite significant improvements in diagnosis delay and treatment strategies, the burden of Systemic Lupus Erythematosus (SLE) remains high. The objective study was to assess association between delay, disease activity on daily life (BoDL) a large sample European patients with SLE. Methods In May 2020, Europe, umbrella patient for SLE, conducted multilingual anonymous online cross-sectional individuals self-reported physician’s SLE living Europe. BoDL score computed using...
Resource consumption is an important topic for steelmaking industry, which spending significant efforts to reduce its environmental impact and improve competitiveness. Water largely exploited in steelworks indirect direct cooling, specific surface treatment, fumes washing cooling. It already reused recycled after restoring quality through treatments temperature and/or pollutant reduction. However, sometimes water networks are not optimized due outdated treatments, lack of continuous...