- Phytochemicals and Antioxidant Activities
- Nonlinear Optical Materials Research
- Bioactive Compounds and Antitumor Agents
- Computational Drug Discovery Methods
- Cholinesterase and Neurodegenerative Diseases
- Essential Oils and Antimicrobial Activity
- Phytochemistry and biological activity of medicinal plants
- Diet, Metabolism, and Disease
- Natural Antidiabetic Agents Studies
- Pharmacological Effects of Natural Compounds
- Helicobacter pylori-related gastroenterology studies
- Ginger and Zingiberaceae research
- Bioactive Compounds in Plants
- Synthesis and Biological Evaluation
- Radioactivity and Radon Measurements
- Regulation of Appetite and Obesity
- Phytochemical compounds biological activities
- Papaya Research and Applications
- MXene and MAX Phase Materials
- Radiation Detection and Scintillator Technologies
- Transgenic Plants and Applications
- Food Science and Nutritional Studies
- Phytochemistry and Biological Activities
- Medicinal Plant Research
- Andrographolide Research and Applications
Hawler Medical University
2023
Ton Duc Thang University
2020
Salahaddin University-Erbil
2005-2016
University of Technology Malaysia
2011-2012
Aqueous and ethanol extracts of different traditional Malaysian plants (Polygonum minus, Andrographis paniculata, Curcuma xanthorrhiza, Momordica charantia Strobilanthes crispus) were evaluated for their antioxidant properties, total phenolic content cytotoxic activity. Antioxidant activity was by using 1,1-diphenyl-1-picrylhydrazyl (DPPH) ferric reducing power (FRAP) assays. The results showed that contain high activities compared to aqueous extracts. findings exhibited a strong correlation...
Theoretical studies on the adsorption, sensibility, and reactivity of a boron nitride nanocage decorated with Au, Cu, Ni, Os, Pt, Zn metals as biosensor material were carried out for adsorption carboplatin by applying density functional theory computation at B3LYP-GD3BJ/def2svp level theory. All optimized structures, well calculations regards studied objective including electronic properties, geometry optimization parameters, energy studies, natural bond orbital analysis, topology sensor...
Orthosiphon stamineus is considered an important traditional folk medicine. In this study ethanol and aqueous extracts of O. were evaluated in vitro for their antioxidant, antimicrobial as well immunomodulatory properties on human peripheral blood mononuclear cells (PBMCs). The DPPH radical scavenging method was used the determination antioxidant activity, while antibacterial efficacy investigated by both disc diffusion Minimum Inhibitory Concentration (MIC) against four bacterial strains...
The leaves of Polygonum minus were fractionated using an eluting solvent to evaluate the pharmacological mechanisms underlying anti-ulcerogenic activity P. minus. Different fractions obtained and evaluated for their ulcer preventing capabilities ethanol induction method. In this study, Sprague Dawley rats weighing 150-200 g used. parameters estimated identify active fraction mechanism gastroprotective action minus: gastric mucus barrier, as well superoxide dismutase, total hexosamine,...
Due to their ubiquity and the rise of drug-resistant forms, Candida albicans infections pose a serious threat world health. Exploring new molecular possibilities is essential in order create newer antifungal medicines address this challenge. Herein, use density functional theory at B3LYP-D3BJ/aug-cc-pVDZ method along with silico docking was utilized examine effects polar (DMSO, ethanol, water) solvation on reactivity, spectral (NMR, UV, FT-IR) investigation, potential...
In recent years, the bioactive properties of medicinal plants have been attracting attention scientists. Polygonum minus Huds is a traditional Malaysian plant that has used in treatment digestive disorders. Several researchers reported that P. contains high level antioxidants, flavonoid and phenolic compounds which contain several properties. To explain mechanism underlying these activities, attempted to determine chemical composition this plant. The aim current study represent previous...
This study have been designed to the effect of extracted pure oleuropein from Oleaeuropaealeaf against alloxan induced type 1 diabetic rats.Diabetic male ratwas by injectingsingle subcutaneous injection 100 mg/kg b.wof alloxan.Respectively, compound (5, 10, 15 and 20 mg/kg.b.w)was orally administered once per a day during period 40 days ofexperiment.Then, serum blood was collected for determination glucose level,haematological analysis, enzymatic non-enzymatic antioxidant. Further,...
Adiponectin is a protein hormone secreted entirely by abdominal fat tissue. It exhibits various biological activities. The present study was performed to evaluate the effects of metformin alone or in combination with adiponectin on blood glucose, TG (triglyceride), CHOL (Total cholesterol), LDL (Low density lipoprotein) and HDL (High levels mice also anti-ulcerogenic activity against ethanol induced gastric mucosal injury rats. Three groups were gavaged 1% volume/body weight high...
The purpose of this study is to evaluate the aqueous extract Alcea kurdica Alef for antioxidant and antimicrobial activity as well potential toxicity. Antioxidant activities were evaluated using 1,1-diphenyl-2- picrylhydrazyl (DPPH) free radical scavenging Ferric Reducing Power (FRAP) reducing capacity assays total phenolic compounds (TPC). Antimicrobial was assessed against some Gram-positive Gram-negative bacteria, yeasts filamentous fungi agar dilution method. plant also in-vitro toxicity...
Acetylcholinesterase (AChE) is a key enzyme enhancing the cognitive disorder, leading to Alzheimer’s disease, and AChE inhibition crucial therapeutic mechanism against it. Matricaria recutita (MR) widely used as herbal medicine due its phytotherapeutic properties. For this reason, MR flower was evaluated identify polyphenolic compounds (PC), then each PC examined for inhibitory activity. The ultra-performance liquid chromatography-electrospray tandem mass spectrometry UPLC-ESI-MS/MS detect...
Medicinal plants have been widely studied to identify plant-based anti-gastric ulcer medicines. The mechanism of gastroprotective action is important discover the potential lead compounds for drug development. All relevant articles between 2011 and 2021 focusing on Malaysian were collected analyzed understand underlying pathways. Keywords include peptic ulcer, gastric NSAIDs (Non-Steroidal Anti-Inflammatory Drugs), Helicobacterpylori, medicinal plant, gastroprotection, antiulcer, acid...