A5047853968- Hepatitis B Virus Studies
- Hepatitis C virus research
- Hepatitis Viruses Studies and Epidemiology
- Viral gastroenteritis research and epidemiology
- Yersinia bacterium, plague, ectoparasites research
- Vibrio bacteria research studies
- Antifungal resistance and susceptibility
- Drug-Induced Hepatotoxicity and Protection
- Antibiotic Resistance in Bacteria
- Phytochemical compounds biological activities
- Garlic and Onion Studies
- Vaccine Coverage and Hesitancy
- Computational Drug Discovery Methods
- Malaria Research and Control
- Fungal Infections and Studies
- Bioactive Compounds in Plants
- Animal Disease Management and Epidemiology
- Liver Disease Diagnosis and Treatment
- Drug-Induced Adverse Reactions
- Escherichia coli research studies
- Antimicrobial Resistance in Staphylococcus
- Pineapple and bromelain studies
- Viral Infections and Outbreaks Research
- Phytochemicals and Antioxidant Activities
- Viral Infections and Immunology Research
Newcastle University Medicine Malaysia
2017
Sana'a University
2007-2016
Universiti Putra Malaysia
2010-2016
University of Malaya
2012
Orthosiphon stamineus is considered an important traditional folk medicine. In this study ethanol and aqueous extracts of O. were evaluated in vitro for their antioxidant, antimicrobial as well immunomodulatory properties on human peripheral blood mononuclear cells (PBMCs). The DPPH radical scavenging method was used the determination antioxidant activity, while antibacterial efficacy investigated by both disc diffusion Minimum Inhibitory Concentration (MIC) against four bacterial strains...
The efficacy of allicin compared with fluconazole in alleviating systemic Candida albicans infections was evaluated both vitro and vivo through a candidiasis mouse model. Determination minimum inhibitory concentrations (MICs) for different C. isolates revealed that showed MICs ranged from 0.05 to 12.5 μg mL−1 0.25 16 mL−1, respectively. A time–kill study significant effect (P <0.01) against albicans, comparable fluconazole. Scanning electron microscopy observation that, similar fluconazole,...
Objectives: This study aimed to evaluate the level of hepatitis B immunity among undergraduate students 23 years after commencement nationwide childhood immunization program in Malaysia. Methods: A total 402 serum samples obtained from volunteer were screened for presence surface antibodies using qualitative ELISA. Results: Results showed that 62.7% volunteers had protective anti-hepatitis antigens (≥10 IU/L), whom 67.9% received three doses vaccine. The estimated post-vaccination was found...
Occult hepatitis B infections are becoming a major global threat, but the available data on its prevalence in various parts of world often divergent.This study aimed to detect occult virus surface antigen-negative serum using anti-HBc as marker previous infection.A total 1000 randomly selected sera from blood donors were tested for core antibody and an ELISA nested polymerase chain reaction was done primers specific gene (S-gene).Of samples 55 (5.5%) found be reactive, which 87.3% (48/55)...
Hepatitis B virus surface mutants are of enormous importance because they capable escaping detection by serology and can infect both vaccinated unvaccinated populations, thus putting the whole population at risk. This study aimed to detect characterise hepatitis B-escaped among blood donors vaccinees. One thousand serum samples were collected for this from antigen, antibodies core tested using a commercial enzyme-linked immunosorbent assay (ELISA) kit. DNA was performed via nested polymerase...
Candida species are a major cause of invasive infections in both critically ill and immunocompromised patients. Hence, rapid identification these pathogens may facilitate specific therapy patient management. The development diagnostic methods remains challenge. Herein, we developed the simplex triplex polymerase chain reaction (PCR) for three medically important namely C. albicans, parapsilosis tropicalis . target phospholipase B gene (PLB). primers designed achieved highly selected using...
epatitis B virus (HBV) vaccines were introduced in the early 1980s, while recombinant hepatitis became available mid-1980s.More than 100 countries have adopted national policy of infant vaccination.Hepatitis Vaccination campaigns been shown to adequately control disease, even endemic areas.The production surface antibodies (anti-HBs) has reported confer long-term protective immunity; these are produced response vaccination or HBV infection.Hepatitis core (anti-HBc), however, detected almost...
Background: Zoonotically acquired HEV has been described as one of the most successful zoonotic viral infections in human history.Aim: In this study we characterized comparative genomic analysis it relates to swine HEV.Materials and methods: A total 82 chronic hepatitis B patients were recruited from May 2015 2016 for study. We conducted a serological molecular investigation among these patients. The detected sequenced genomes deduced amino acids using evolutionary genetic software version...
<i>Objective:</i> The aim of this study was to determine the sensitivities <i>Plasmodium falciparum</i> clinical isolates sulfadoxine/pyrimethamine (SP) using in vivo and vitro methods. <i>Subjects Methods:</i> In Mark III in-vitro test techniques according World Health Organization protocols antimalarial drug tests were used SP susceptibility <i>P. from 100 malaria patients both sexes between ages 3.5 45 years living Tihamah, Yemen. conducted 19...
Occult hepatitis B is characterized by undetectable levels of surface antigen, but detectable viral DNA and becoming a major global threat due to: (i) the effect on health children born to carrier mothers despite presence passive immunoglobulin at birth; (ii) immune escape current vaccines; (iii) spread through blood products in post transfusion infection, organ donation, sexual transmission. The aim this study investigate occult virus among vaccines. Four hundred eight, vaccinee were...