A5103093120- Natural product bioactivities and synthesis
- Forensic Toxicology and Drug Analysis
- Ginger and Zingiberaceae research
- Nigella sativa pharmacological applications
- Phytochemicals and Antioxidant Activities
- Essential Oils and Antimicrobial Activity
- Drug-Induced Hepatotoxicity and Protection
- Phytochemistry and Biological Activities
- Bee Products Chemical Analysis
- Genomics, phytochemicals, and oxidative stress
- Bioactive natural compounds
- Hormonal and reproductive studies
- Helicobacter pylori-related gastroenterology studies
- Pharmacological Effects of Natural Compounds
- Bioactive Compounds and Antitumor Agents
- Natural Antidiabetic Agents Studies
- Alcohol Consumption and Health Effects
- Computational Drug Discovery Methods
- Artificial Intelligence in Healthcare and Education
- Neurotransmitter Receptor Influence on Behavior
- Advances in Cucurbitaceae Research
- Sesquiterpenes and Asteraceae Studies
- Natural Compounds in Disease Treatment
- Pesticide Exposure and Toxicity
- Plant Genetic and Mutation Studies
Jazan University
2016-2025
Médecins Sans Frontières
2025
Ludwig-Maximilians-Universität München
2022-2025
Huazhong Agricultural University
2024
Health Affairs
2024
Directorate of Health
2024
Al-Neelain University
2024
Weatherford College
2023
LMU Klinikum
2022-2023
University of Mosul
2022
Jasminum sambac is used in folk medicine as the treatment of many diseases. The aim present investigation to evaluate gastroprotective effects ethanolic extracts J. leaves against acidified ethanol-induced gastric ulcers rats. Seven groups rats were orally pre-treated with carboxymethylcellulose (CMC) normal group, CMC ulcer 20 mg/kg omeprazole positive 62.5, 125, 250, and 500 extract experimental groups, respectively. An hour later, was given group ethanol solution control, groups....
Background: Nanostructured lipid carriers (NLCs), composed of solid and liquid lipids, surfactants are potentially good colloidal drug carriers. Thymoquinone is the main bioactive compound Nigella sativa . In this study, preparation, gastroprotective effects, pharmacokinetic (PK) properties thymoquinone (TQ)-loaded NLCs (TQNLCs) were evaluated. Method: TQNLCs prepared using hydrogenated palm oil (Softisan ® 154), olive oil, phosphatidylcholine for phase sorbitol, polysorbate 80, thimerosal,...
Background Zingiber zerumbet Smith is a perennial herb, broadly distributed in many tropical areas. In Malaysia, it's locally known among the Malay people as "lempoyang" and its rhizomes, particularly, widely used traditional medicine for treatment of peptic ulcer disease beyond other gastric disorders. Aim study The aim current to evaluate gastroprotective effect zerumbone, main bioactive compound rhizome, against ethanol-induced model rats. Materials Methods Rats were pre-treated with...
Nanotechnology is a rapidly expanding discipline, and solid lipid nanoparticles (SLN) are at the forefront of this development. They offer various possible clinical pharmaceutical research applications numerous other fields. A quantitative review technique called bibliometric analysis uses statistics, data mining, mathematics to find emerging trends in particular academic topic. It currently more widely utilized employed many subjects. As result, current study looked through Scopus-indexed...
The current in vitro study was designed to investigate the anti-inflammatory, cytotoxic and antioxidant activities of boesenbergin A (BA), a chalcone derivative known structure isolated from Boesenbergia rotunda. Human hepatocellular carcinoma (HepG2), colon adenocarcinoma (HT-29), non-small cell lung cancer (A549), prostate (PC3), normal hepatic cells (WRL-68) were used evaluate cytotoxicity BA using MTT assay. activity assessed by ORAC assay compared quercetin as standard reference...
The essential oil of the bark Cinnamomum altissimum Kosterm. obtained by hydrodistillation was analyzed capillary GC and GC–MS. characterized linalool (36.0%), methyl eugenol (12.8%), limonene (8.3%), α-terpineol (7.8%) terpinen-4-ol (6.4%). content total phenolics in extracts determined spectrometrically according to Folin–Ciocalteu procedure calculated as gallic acid equivalents (GAE). A phenolic compound 50.41 ± 0.98 μg GAE/mg oil. extract displayed antioxidant activities, with an IC50...
Mitrella kentii (M. kentii) (Bl.) Miq, is a tree-climbing liana that belongs to the family Annonaceae. The plant rich with isoquinoline alkaloids, terpenylated dihydrochalcones and benzoic acids has been reported possess anti-inflammatory activity. purpose of this study assess gastroprotective effects desmosdumotin C (DES), new isolated bioactive compound from M. kentii, on gastric ulcer models in rats.
This study investigated the potential hepatoprotective activity of curcumin-incorporated nano-lipid carrier (Cur-NLC) against cypermethrin (Cyp) toxicity in adult Wistar male rats. All animals groups III, IV, V, and VI were subjected to Cyp (50 mg/kg) for 15 days. Three different doses Cur-NLC (1, 2.5, 5 mg/kg/day) administered orally 10 The toxic effects evaluated considering increases serum hepatic biomarkers alanine aminotransferase (ALT), aspartate (AST), alkaline phosphatase (ALP),...
This study was set to investigate antiproliferative potential of dentatin (a natural coumarin isolated from Clausena excavata Burm. F) against prostate cancer and delineate the underlying mechanism action. Treatment with dose-dependently inhibited cell growth PC-3 LNCaP lines, whereas it showed less cytotoxic effects on normal epithelial line (RWPE-1). The inhibitory effect due induction apoptosis as evidenced by Annexin V staining shrinkage. We found that dentatin-mediated accumulation...
Acne vulgaris is a common skin disease that has physical and psychological impacts. Patients diagnosed with acne often use complementary alternative medicine, despite the insufficient evidence.
Abstract Gum Arabic (GA) is a natural ingredient used in food, pharmaceutical, and cosmetic industries. Numerous studies have been conducted on the physicochemical properties applications of GA. This study aimed to map knowledge perform bibliometric analysis GA research (GAR) for over century ago. A search was carried out Scopus database using relevant terms Boolean operators (Gum OR Acacia gum, gum sudani), data-driven documents English were extracted. The extracted data included citations,...