A5009345910- Virus-based gene therapy research
- Toxic Organic Pollutants Impact
- Mosquito-borne diseases and control
- Carcinogens and Genotoxicity Assessment
- Animal Virus Infections Studies
- HIV Research and Treatment
- Drug-Induced Hepatotoxicity and Protection
- Nephrotoxicity and Medicinal Plants
- Solar and Space Plasma Dynamics
- Animal Disease Management and Epidemiology
- Inertial Sensor and Navigation
- Vector-borne infectious diseases
- Actinomycetales infections and treatment
- Effects and risks of endocrine disrupting chemicals
- Diphtheria, Corynebacterium, and Tetanus
- Viral Infections and Vectors
- Prion Diseases and Protein Misfolding
- Viral gastroenteritis research and epidemiology
- CRISPR and Genetic Engineering
- Infectious Disease Case Reports and Treatments
- Veterinary Medicine and Surgery
- Ovarian cancer diagnosis and treatment
- Eicosanoids and Hypertension Pharmacology
- Geomagnetism and Paleomagnetism Studies
- Adrenal and Paraganglionic Tumors
Colorado State University
2023-2024
National Institutes of Health
2023
National Cancer Institute
2023
University of California, Davis
2014-2021
University of Stuttgart
2013
Background:The aryl hydrocarbon receptor repressor (AhRR) is known to repress (AhR) signaling, but very little regarding the role of AhRR in vivo.Objective:This study tested vivo overexpressing mice on molecular and toxic end points mediated through a prototypical AhR ligand.Methods:We generated AhRR-transgenic (AhRR Tg) based genetic background C57BL/6J wild type (wt) mice. We effect ligand 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) expression cytochrome P450 (CYP)1A1 cytokines various...
Feline infectious peritonitis (FIP), caused by genetic mutants of feline enteric coronavirus known as FIPV, is a highly fatal disease cats with no currently available vaccine or US Food and Drug Administration-approved cure. Dissemination FIPV in affected results range clinical signs, including cavitary effusions, anorexia, fever lesions pyogranulomatous vasculitis perivasculitis, without central nervous system ocular involvement. The objectives this study were to screen an array antiviral...
Caprine arthritis encephalitis virus (CAEV) is a monocyte/macrophage-tropic lentivirus that primarily infects goats resulting in well-recognized set of chronic inflammatory syndromes focused on the joint synovium, tissues central nervous system, pulmonary interstitium and mammary gland. Clinically affected animals generally manifest with one or more these classic CAEV-associated tissue lesions; however, renal inflammation has not been reported peer-reviewed literature. Here we describe six...
Modern antiretroviral therapy for immunodeficiency viruses, although remarkably effective in controlling viral transcription, and overt virus-associated morbidity, has failed to absolutely eradicate retroviruses from their infected hosts as a result of proviral integration long-lived reservoir cells. Immunodeficiency virus-infected patients are therefore consigned lifelong antiviral means control viremia, transmission, infection-associated morbidity. Unfortunately, therapies can be difficult...
Abstract Feline infectious peritonitis (FIP), caused by a genetic mutant of feline enteric coronavirus known as FIPV, is highly fatal disease cats with no currently available vaccine or FDA-approved cure. Dissemination FIPV in affected results range clinical signs including cavitary effusions, anorexia, fever and lesions pyogranulomatous vasculitis peri-vasculitis without central nervous system and/or ocular involvement. There critical need for effective approved antiviral therapies against...
This paper presents a commonly used magnetic momentum controller for satellites augmented with an L1 adaptive controller. In particular, the main objective of study is to investigate ability control improve de-saturation performance and add more robustness existing architecture in presence uncertainties geomagnetic field model available on-board design. Existing non-adaptive controllers use Earth’s measurements or fairly accurate models. The results presented this suggest that able provide...
Abstract Tubulointerstitial nephropathy and uveitis, otherwise more broadly known as oculorenal syndrome in human medicine, is a condition that has, to the authors’ knowledge, not been described veterinary medicine. This report describes an 8‐year‐old, male, neutered, mixed breed dog with 6‐year history of idiopathic epilepsy, chronically receiving zonisamide, who was presented for sub‐acute recurrent episodes severe generalised weakness, altered mentation inappropriate urination. Throughout...
A female goat fetus was received by the Colorado State University–Veterinary Diagnostic Laboratory following an isolated abortion of twins a reportedly healthy doe. Postmortem examination did not reveal any gross abnormalities. Histologic evaluation revealed pyogranulomatous and necrotizing bronchopneumonia with intracellular extracellular gram-positive non–acid-fast filamentous bacilli. Aerobic culture stomach contents pooled lung liver tissue yielded light growth Nocardia sp., which...
Abstract OBJECTIVE To describe the use of ultrasound and adrenal function testing to confirm that excised periovarian tissue is normal ectopic (EAT). ANIMAL A 6-month-old female domestic shorthair cat. CLINICAL PRESENTATION, PROGRESSION, AND PROCEDURES The cat underwent an ovariohysterectomy procedure, during which abnormal was discovered adjacent both ovaries. removed submitted for histopathology, consistent with gland tissue, initially raising concern inadvertent adrenalectomy. Abdominal...