A5077405693- Bacterial biofilms and quorum sensing
- Biochemical and Structural Characterization
- Antimicrobial agents and applications
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Resistance in Bacteria
- Wound Healing and Treatments
- Microbial Natural Products and Biosynthesis
- Microplastics and Plastic Pollution
- Pineapple and bromelain studies
Universidade Federal Fluminense
2016-2023
Diabetic patients frequently develop wounds, which can be colonized by bacteria, mainly Staphylococcus aureus and Pseudomonas aeruginosa, with the ability to form biofilms. This study aimed evaluate colonization biofilm formation of aeruginosa in chronic wounds diabetic treated a bioactive dressing (EGF-CMC), consisted 2% carboxymethylcellulose (CMC) hydrogel loaded epidermal growth factor (EGF). randomized clinical trial was conducted 25 participants: 14 EGF-CMC 11 CMC for 12 weeks....
Pseudomonas aeruginosa is a common pathogen of acute and chronic infections that can increase risk to burned patients those with wounds, especially when forming biofilms. These complex ecosystems are formed by several bacteria communicate, cooperate, compete each other. To enhance its survival capacity in such competitive environment, P. produces secondary metabolites range biological activities, among other factors. Here, we evaluated how bioactive molecules mediate intraspecies...
Bromelain is a set of proteolytic enzymes usually obtained from pineapple (Ananas comosus). Although bromelain has distinguished therapeutic properties, little known about its potential against opportunistic pathogens related to wound healing complications, such as Staphylococcus aureus. This study aimed investigate the antibiofilm and antibacterial activity in 43 clinical strains S. aureus isolated chronic wounds blood cultures. Bromelain’s biofilm vitro was assessed by analyzing formation...
Pseudomonas aeruginosa é um dos patógenos mais frequentes em infecções acometendo pacientes queimados, tendo como importante determinante de patogenicidade sua capacidade formar biofilmes. O presente trabalho tem por objetivo avaliar a eficácia das soluções biocidas: clorexidina 4%, hipoclorito sódio 1%, peróxido hidrogênio 5% e álcool 70% na remoção biofilmes P. multidroga resistentes. Trata-se estudo descritivo abordagem quantitativa. Foram avaliados nove cepas aeruginosa, diferentes tipos...