- Sarcoidosis and Beryllium Toxicity Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Inflammasome and immune disorders
- Breast Cancer Treatment Studies
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Photosynthetic Processes and Mechanisms
- Lung Cancer Treatments and Mutations
- Radiomics and Machine Learning in Medical Imaging
- Breast Lesions and Carcinomas
- Cancer Immunotherapy and Biomarkers
- Plant Molecular Biology Research
- Light effects on plants
Qinghai University Affiliated Hospital
2025
Qinghai University
2022-2024
Southern Medical University
2022
XinHua Hospital
2012
Yale University
2001
Arabidopsis seedling photomorphogenesis involves two antagonistically acting components, COP1 and HY5. specifically targets HY5 for degradation via the 26 S proteasome in dark through their direct physical interaction. Little is known regarding how light signals perceived by photoreceptors are transduced to regulate COP1. has related cryptochromes (cry1 cry2) mediating various blue/ultraviolet-A responses. Here we show that both photoactivated repress activity a protein-protein contact this...
Abstract We aimed to evaluate the efficacy and safety of adding apatinib, sintilimab chemotherapy in neoadjuvant treatment early triple-negative breast cancer (TNBC). In phase 2 NeoSAC trial, patients with TNBC received six cycles sintilimab, nab-paclitaxel, carboplatin followed by surgery. The primary endpoint was pathological complete response (pCR) rate. Specimens collected pre-neoadjuvant therapy post-surgery were retained for comprehensive analysis predictive biomarkers impact on tumor...
Based on the strong antioxidant activity of anthocyanins, this study was aimed to explore potential influence Lycium ruthenicum Murry anthocyanins (LRMA) hypoxia-induced apoptosis and proliferation H9c2 rat cardiomyocytes. The cell viability first tested after exposure normoxia, hypoxia, hypoxia + LRMA. After being incubated for 12 h under normoxia 24 in 50 μg/mL LRMA or 100 μM Salidroside, respectively, LDH content, morphology, cycle progression were analyzed. In addition, cellular along...