A5108137503- Atherosclerosis and Cardiovascular Diseases
- Neuroinflammation and Neurodegeneration Mechanisms
- Viral Infections and Vectors
- Acute Ischemic Stroke Management
- Lipoproteins and Cardiovascular Health
- Immune cells in cancer
- Cancer Cells and Metastasis
- Amphibian and Reptile Biology
- Cancer, Lipids, and Metabolism
- Rabies epidemiology and control
- Bartonella species infections research
- Leptospirosis research and findings
- Hormonal Regulation and Hypertension
- Ferroptosis and cancer prognosis
Yunnan Institute of Endemic Diseases Control and Prevention
2022-2023
Hunan Provincial People's Hospital
2021-2022
Abstract Background The immune system plays a vital role in the pathological process of ischaemic stroke. However, exact immune-related mechanism remains unclear. current research aimed to identify key genes associated with Methods CIBERSORT was utilized reveal cell infiltration pattern stroke patients. Meanwhile, weighted gene coexpression network analysis (WGCNA) meaningful modules significantly correlated characteristic were identified by following two machine learning methods: support...
Background: Abnormalities in the extracellular matrix (ECM) have been shown to play a crucial role promoting formation, progression, and metastasis of glioblastoma multiforme (GBM). Therefore, our study is aimed at constructing prognostic model based on ECM‐related factors, predict prognosis patients with GBM. Methods: We employed single‐sample gene set enrichment analysis (ssGSEA) establish ECM index The identification candidate genes was achieved by differential conducted between groups,...
Leptospirosis has been identified as a zoonotic disease caused by pathogenic spirochetes of the bacterial genus Leptospira. Rodents are considered primary hosts these bacteria, whereas many recent studies suggest that bats may serve potential natural reservoirs. However, on hosted bat populations still need to be completed in China. In this study, total 276 belonging five genera collected Yunnan Province (Southwest China) from 2017 2021 were included screening. Pathogenic detected PCR...
Bartonella species has been validated as blood-borne bacteria in mammals and a substantial opportunity to be harbored by variety of hematophagous arthropod vectors. Bats, along with their ectoparasites, are recognized worldwide one the natural reservoir hosts for these bacteria. However, there have few investigations toward broad range obligated bat ectoparasites China. Here, molecular detection was performed survey infection among follow-up phylogenetic analyses further characterize...
Abstract Background: The purpose of this study was to explore the potential molecular targets hyperlipidaemia and related mechanisms. Methods: microarray dataset GSE66676 obtained from patients with downloaded. Weighted gene co-expression network (WGCNA) analysis used analyse expression profile, royal blue module considered have highest correlation. Gene Ontology (GO) functional Kyoto Encyclopedia Genes Genomes (KEGG) pathway enrichment analyses were implemented for identification genes in...