Bin-Na Lee

ORCID: 0000-0001-8017-1835
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About
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Research Areas
  • Endodontics and Root Canal Treatments
  • Dental materials and restorations
  • Dental Radiography and Imaging
  • Dental Trauma and Treatments
  • Bone Tissue Engineering Materials
  • Bone and Dental Protein Studies
  • Dental Erosion and Treatment
  • dental development and anomalies
  • Dental Implant Techniques and Outcomes
  • Oral microbiology and periodontitis research
  • 3D Printing in Biomedical Research
  • Oral and Maxillofacial Pathology
  • Photopolymerization techniques and applications
  • Temporomandibular Joint Disorders
  • HIV Research and Treatment
  • Biochemical Analysis and Sensing Techniques
  • Dental Research and COVID-19
  • Salivary Gland Disorders and Functions
  • Laser Applications in Dentistry and Medicine
  • Bone Metabolism and Diseases
  • Bone health and treatments
  • Additive Manufacturing and 3D Printing Technologies
  • Surgical Sutures and Adhesives
  • Occupational health in dentistry
  • Drilling and Well Engineering

Chonnam National University
2016-2025

Gwangju Institute of Science and Technology
2018

The University of Texas MD Anderson Cancer Center
1996-1997

The purpose of this study was to assess the ability two new calcium silicate-based pulp-capping materials (Biodentine and BioAggregate) induce healing in a rat pulp injury model compare them with mineral trioxide aggregate (MTA).Eighteen rats were anesthetized, cavities prepared capped either ProRoot MTA, Biodentine, or BioAggregate. specimens scanned using high-resolution micro-computed tomography (micro-CT) system evaluated histologically immunohistochemically dentin sialoprotein (DSP).On...

10.5395/rde.2016.41.1.29 article EN cc-by-nc Restorative Dentistry & Endodontics 2016-01-01

Abstract Aim To compare the mineralization inductive capacity of Biodentine and Bioaggregate with Mineral trioxide aggregate ( MTA ) to investigate possible signaling pathways in human dental pulp cells HDPC s). Methodology Viability s response Biodentine, Bioaggregate, was measured using 3‐[4,5‐dimethylthiazol‐2‐yl]‐2,5 diphenyltetrazolium bromide. their potential induce odontoblast differentiation, expression dentine sialophosphoprotein DSPP matrix protein1 DMP 1) m RNA level evaluated by...

10.1111/iej.12298 article EN International Endodontic Journal 2014-04-16

Introduction: Previous studies have shown that bioactive glass (BG) can enhance the formation of hydroxyapatite under simulated body fluid (SBF) conditions when combined with mineral trioxide aggregate (MTA). This study aims to assess impact BG-supplemented MTA on biocompatibility and mineralization potential dental pulp stem cells (DPSCs). Methods: We prepared ProRoot (MTA) supplemented 2% 4% BG. Five passages DPSCs were utilized for experiments. The subjected various tests determine their...

10.34133/bmr.0142 article EN cc-by Biomaterials Research 2025-01-17

The aim of this study was to evaluate the cytotoxicity, setting time and compressive strength MTA two novel tricalcium silicate-based endodontic materials, Bioaggregate (BA) Biodentine (BD).Cytotoxicity evaluated by using a 2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-5-((phenylamino)carbonyl)-2H-tetrazolium hydroxide (XTT) assay. Measurements 9 heavy metals (arsenic, cadmium, chromium, copper, iron, lead, manganese, nickel, zinc) were performed inductively coupled plasma-mass spectrometry...

10.5395/rde.2014.39.2.89 article EN cc-by-nc Restorative Dentistry & Endodontics 2014-01-01

Various three-dimensional (3D) culture methods have been introduced to overcome the limitations of in vitro and mimic vivo conditions. This study aimed evaluate two microsphere-forming a monolayer method. We evaluated cell morphology, viability, osteo-, adipo-, chondrogenic differentiation potential dental pulp stem cells (DPSCs) cultured 3D plates: ultra-low attachment (ULA) U-bottomed StemFit (SF) plates, two-dimensional (2D) plate. RNA sequencing (RNA-seq) revealed differentially...

10.3390/jcm9010242 article EN Journal of Clinical Medicine 2020-01-16

Purpose This study aims to compare the volumetric change, degree of conversion (DOC), and cytotoxicity 3D-printed restorations post-cured under three different conditions. Materials methods interim were conditions systems: 5 min, 30 24 h. Three-unit six-unit fixed dental prostheses (n = for each case) printed; ten specimens from group then scanned their changes. Root-mean-squared (RMS) values data acquired by superimposing files with original files. Thirty disk-shaped printed evaluate DOC...

10.4047/jap.2021.13.2.71 article EN The Journal of Advanced Prosthodontics 2021-01-01

A calcium silicate cement/methacrylated gelatin (GelMa) scaffold has been applied in tissue engineering; however, the research on its applications dental regeneration remains lacking. We investigate effect of this human pulp stem cells (hDPSCs). hDPSCs were cultured 3D-printed GelMa and MTA-GelMa scaffolds. Cell adhesion was evaluated using scanning electron microscopy images. Cells an osteogenic differentiation medium, which contained a complete medium or α-MEM containing aqueous extracts...

10.3390/ma15062170 article EN Materials 2022-03-15

The inflammatory cytokines interleukin-1beta (IL-1beta), IL-6, and tumor necrosis factor alpha (TNF-alpha) have been associated with increased human immunodeficiency virus (HIV) expression enhanced lymphocyte adhesion to trophoblastic cells in experimental systems. To determine if there is a correlation between the of these levels HIV transcripts trophoblasts term placentas from HIV-infected women, we studied placentae 30 HIV-positive 13 control gravidae. Twenty-three women received...

10.1128/jvi.71.5.3628-3635.1997 article EN Journal of Virology 1997-05-01

Background and Objectives: Bromelain is a mixture of protease obtained from pineapple fruits or stems. Even though the biological mechanism action bromelain has not been completely understood, it well known that possesses anticancer, anti-inflammatory immunomodulatory effects. This study investigated effects on lipopolysaccharide (LPS)-induced human dental pulp cells (hDPCs). Materials Methods: Cell viability after treatment was measured using WST-1 assay. We exposed hDPCs to 5 µg/mL LPS...

10.3390/medicina57060591 article EN cc-by Medicina 2021-06-08

Dental management of patients with X-linked hypophosphatemiaX-linked hypophosphatemia (XLH) is a hereditary metabolic disease caused by the loss phosphate through renal tubules into urine, and an associated decrease in serum calcium potassium phosphate.Its dental features include spontaneous abscesses that occur absence trauma or caries.The aim this case report was to describe problems XLH evaluate limitations their treatment.A 14 year old male 38 female were referred Department Conservative...

10.5395/rde.2017.42.2.146 article EN cc-by-nc Restorative Dentistry & Endodontics 2017-01-01

The purpose of this study was to investigate the polymerization temperature a bulk filled composite resin light-activated with various light curing modes using infrared thermography according depth and approximation cavity wall.Composite (AeliteFlo, Bisco, Schaumburg, IL, USA) inserted into Class II prepared in Teflon blocks cured LED unit (Dr's Light, GoodDoctors Co., Seoul, Korea) for 20 s. Polymerization measured an thermographic camera (Thermovision 900 SW/TE, Agema Infra-red Systems AB,...

10.1590/1678-775720130036 article EN cc-by Journal of Applied Oral Science 2013-07-01

Treatment of non-vital immature teeth with amoxicillin-containing triple antibiotic paste resulting in apexificationA recent treatment option for young patients is revascularization (TAP).However, tooth discoloration was reported the use conventional minocycline-containing TAP.In this case report, TAP used to prevent discoloration.At 1 yr follow up, were asymptomatic on clinical examination and showed slight crown due mineral trioxide aggregate (MTA) filling rather than TAP.Radiographic...

10.5395/rde.2015.40.4.322 article EN cc-by-nc Restorative Dentistry & Endodontics 2015-01-01

To assess the biological effects, including odontoblastic differentiation of a novel light-curable material (TheraCal), on human dental pulp cells (hDPCs).The hDPCs were isolated from freshly extracted, caries-free third molars. Ten discs TheraCal and MTA (8 mm in diameter 3 height) incubated α-minimum essential medium (α-MEM) supernatant collected. Viability response to was measured using WST-1 assay. RT-PCR real-time PCR used detect gene expression dentine sialophosphoprotein (DSPP) matrix...

10.1111/iej.12642 article EN International Endodontic Journal 2016-03-25
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