A5067814848- Hair Growth and Disorders
- Dermatologic Treatments and Research
- Patient Dignity and Privacy
- melanin and skin pigmentation
- Palliative Care and End-of-Life Issues
- Mesenchymal stem cell research
- Facial Rejuvenation and Surgery Techniques
- Cancer and Skin Lesions
- Skin and Cellular Biology Research
- Fibroblast Growth Factor Research
- Wnt/β-catenin signaling in development and cancer
- Patient-Provider Communication in Healthcare
- Nerve injury and regeneration
- Cancer-related molecular mechanisms research
- Body Contouring and Surgery
- Mast cells and histamine
- Click Chemistry and Applications
- Orthodontics and Dentofacial Orthopedics
- Childhood Cancer Survivors' Quality of Life
Southern Medical University
2017-2024
Nanfang Hospital
2020-2024
Sun Yat-sen University
2023-2024
Sun Yat-sen Memorial Hospital
2023-2024
Peking University
2019
Peking University Cancer Hospital
2019
Zhujiang Hospital
2017-2019
The restoration of hair-inductive potential in human dermal papilla cells (hDPCs) is a tremendous challenge for hair regeneration. Much the research thus far has indicated that three-dimensional (3-D) culture shows improved efficacy follicle (HF) neogenesis. However, mature HF cannot regenerate an incomplete microenvironment. This study developed optimized 3-D co-culture system to restore characteristics hDPCs by mimicking in-vivo As result, Matrigel-encapsulated spontaneously formed into...
Depletion or permanent quiescence of the hair follicle stem cell (HFSC) pool underlies pathogenesis in androgenetic alopecia (AGA). Reactivation quiescent HFSCs is considered an efficient treatment strategy for loss. The retinoic acid (RA) critical to ensure homeostasis and function. However, little known about whether RA regulates HFSC homeostasis. We aimed investigate impact on underlying mechanisms, order provide new potential targets medical therapies AGA.
The application of dermal papilla cells to hair follicle (HF) regeneration has attracted a great deal attention. However, cultured (DPCs) tend lose their capacity induce growth during passage, restricting usefulness. Accumulating evidence indicates that DPCs regulate HF mainly through unique paracrine properties, raising the possibility therapies based on extracellular vesicles (EVs). In this study, we explored effects EVs from high- and low-passage human scalp (DP-EVs) activation growth,...
Hair follicle tissue engineering is a promising strategy for treating hair loss. Human stem cells (hHFSCs), which play key role in the cycle, have potential applications regenerative medicine. However, previous studies did not achieve efficient hHFSC expansion vitro using feeder cells. Therefore, there need to develop an primary culture system and maintenance of hHFSCs.The hHFSCs were obtained by two-step proteolytic digestion combined with microscopy. The cell dishes coated human...
Objective The aim of this study was to describe preferences for a good death among Chinese patients with advanced cancer and then explore factors contributing their including patient demographics disease variables. Methods A convenience sample 275 recruited from tertiary hospital in Beijing, China, between February December 2017. version the Good Death Inventory (GDI) used measure patients’ dying death. Besides, data were collected using multi-itemed questionnaire focusing on demographic...
According to the volume restoration theory, lower facial fat compartments tend selectively atrophy or hypertrophy with age. The aim of this study was demonstrate age-related changes in using computed tomography, strict control body mass index and underlying diseases.
To investigate the effect of tranilast on wound healing and mechanism inhibiting scar hyperplasia in mice, to study relationship between ability administration time.Sixty-six Kunming mice were selected build deep II degree burn model, randomly divided into control group (18 mice), early intervention medium late (12 mice). The group, medium-term given 200 mg/(kg·d) by gastrogavage at immediate, 7 days, 14 days after respectively, managed with same amount normal saline every day. was observed...