A5023221174- S100 Proteins and Annexins
- Biomarkers in Disease Mechanisms
- Occupational and environmental lung diseases
- Cancer, Stress, Anesthesia, and Immune Response
- Medical and Biological Ozone Research
- Cancer, Hypoxia, and Metabolism
- Galectins and Cancer Biology
- Cardiac, Anesthesia and Surgical Outcomes
- Medical Imaging and Pathology Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Molecular Biology Techniques and Applications
- RNA Research and Splicing
- Therapeutic Uses of Natural Elements
- Signaling Pathways in Disease
- Neonatal Respiratory Health Research
- Cytokine Signaling Pathways and Interactions
- Protease and Inhibitor Mechanisms
- Genomics and Phylogenetic Studies
- Estrogen and related hormone effects
The University of Melbourne
2014-2021
Second Military Medical University
2016
Second Affiliated Hospital of Nanchang University
2014
Nanchang University
2014
Transforming growth factor-beta (TGF-β) is a major mediator of fibrotic diseases, including idiopathic pulmonary fibrosis (IPF). However, therapeutic global inhibition TGF-β limited by unwanted immunosuppression and mitral valve defects. We performed an extensive literature search to uncover little-known connection between signalling casein kinase (CK) activity. have examined the abundance CK1 delta epsilon (CK1δ/ε) in lung tissue from IPF patients non-diseased controls, investigated whether...
Abstract Glucocorticoids are commonly used to prevent chemotherapy-induced nausea and vomiting despite a lack of understanding their direct effect on cancer progression. Recent studies suggest that glucocorticoids inhibit cell migration. However, this action has not been investigated in estrogen receptor (ER)-negative breast tumour cells, although activation the glucocorticoid (GR) is associated with worse prognosis ER-negative cancers. In study we have explored migration MDA-MB-231 human...
Safflower (Carthamus tinctorius L., Asteraceae) is an important oil crop and medicinal plant. Gene expression analysis gaining importance in the research of safflower. Quantitative PCR has become a powerful method for gene study. Reference genes are one major qualification requirements qPCR because they can reduce variability. To identify reference safflower, nine candidate housekeeping were selected from EST library safflower constructed by our lab: CtACT (actin), CtGAPDH (glyceraldehyde...
Triple-negative breast cancer (TNBC) has a poor outcome compared to other subtypes, and new therapies that target the molecular alterations driving tumor progression are needed. Annexin A1 is an abundant multi-functional Ca2+ binding membrane-associated protein. Reported roles of in metastasis contradictory. Here, we sought clarify functions development TNBC. The association expression with patient prognosis subtypes TNBC was examined. stably knocked down panel human murine cell lines high...
The Journal of Cancer Metastasis and Treatment is an open access journal focused on cancer metastasis treatment, including the occurrence, development, progression, metastasis, treatment oncologic disease. It covers basic, translational clinical research related to cell biology, genomics, precision medicine, oncology internal radiotherapy radiology, obstetrics gynecology, pediatrics, surgery, hematology, neurooncology, etc.
To investigate the role of CD147 gene on proliferation and infiltration a human monocytic leukemic cell line SHI-1.The expression in SHI-1 cells was knockdowned by lentiviral vector. The expressions CD147, MMP-2 MMP-9 were detected semiquantitative RT-PCR. protein Western blotting. capabilities examined MTT trans- matrigel invasion assay co-cultured with leukemia BMSC vitro. inoculated subcutaneously or via tail vein into nude mice to its growth infiltrative ability vivo.The mRNA...