Nicholas Crump

ORCID: 0000-0001-8040-9487
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About
Contact & Profiles
Research Areas
  • Peripheral Neuropathies and Disorders
  • Peripheral Nerve Disorders
  • Myasthenia Gravis and Thymoma
  • Hereditary Neurological Disorders
  • Multiple Sclerosis Research Studies
  • Orthopedic Surgery and Rehabilitation
  • Delphi Technique in Research
  • Cerebral Venous Sinus Thrombosis
  • Congenital Diaphragmatic Hernia Studies
  • Cardiovascular Effects of Exercise
  • Innovations in Medical Education
  • Glioma Diagnosis and Treatment
  • Ultrasound in Clinical Applications
  • Respiratory Support and Mechanisms
  • Eosinophilic Disorders and Syndromes
  • Neurological Complications and Syndromes
  • Trace Elements in Health
  • Rheumatoid Arthritis Research and Therapies
  • Acute Ischemic Stroke Management
  • Clinical practice guidelines implementation
  • Neurological diseases and metabolism
  • Stroke Rehabilitation and Recovery
  • Pituitary Gland Disorders and Treatments
  • Sports injuries and prevention
  • Radioactive Decay and Measurement Techniques

Austin Health
2012-2024

The University of Melbourne
2019-2023

Wake Forest University
2021

University of Chicago
2016

Austin Hospital
2012-2013

Geelong Hospital
2005

Barwon Health
2005

Abstract Neuromuscular ultrasound has become an essential tool in the diagnostic evaluation of various neuromuscular disorders, and, as such, there is growing interest training. Effective training critical mastering this modality. Our aim was to develop consensus‐based guidelines for courses. A total 18 experts participated. Expert opinion sought through Delphi method using 4 consecutive electronic surveys. high degree consensus achieved with regard general structure training; categorization...

10.1002/mus.26642 article EN Muscle & Nerve 2019-07-23

Background High‐intensity resistance training ( HIRT ) programmes are increasingly popular amongst personal trainers and those attending gymnasiums. We report the experience of exertional rhabdomyolysis ER at two tertiary hospitals in Melbourne, Australia. Aims To compare clinical outcomes with other causes rhabdomyolysis. Methods Retrospective cross‐sectional study patients presenting a serum creatine kinase CK greater than 25 000 units/L from 1 September 2013 to 31 August 2014 referral...

10.1111/imj.13055 article EN Internal Medicine Journal 2016-03-07

Guillain-Barré syndrome (GBS) is an immune-mediated disease characterised by evolving ascending limb weakness, sensory loss and areflexia. Two-thirds of GBS cases are associated with preceding infection. However, has also been described in association antitumour necrosis factor (TNF) therapies including infliximab adalimumab for chronic inflammatory disorders such as rheumatoid arthritis, ankylosing spondylitis bowel disease. We present the case a patient who developed while undergoing...

10.1136/bcr-2017-219481 article EN BMJ Case Reports 2017-07-05

Neuromuscular ultrasound has become an integral part of the diagnostic workup neuromuscular disorders at many centers. Despite its growing utility, uniform standard scanning techniques do not currently exist. Scanning approaches for similar diseases vary in literature creating heterogeneity studies as reported several meta-analysis. Moreover, experts including group this study have different views with regards to technical aspects, protocols, and parameters that should be assessed....

10.1002/mus.27830 article EN Muscle & Nerve 2023-04-19

Abstract Neuromuscular ultrasound is a rapidly evolving specialty with direct application for patient care. Competency assessment an essential standard needed to ensure quality practitioners, particularly those newly acquiring skills the technique. Our aim was survey experts' opinions regarding physician competency of neuromuscular and identify minimal knowledge skills. The 18 experts were obtained through Delphi method using two consecutive electronic surveys. A high degree consensus...

10.1002/mus.27163 article EN Muscle & Nerve 2020-12-31

A 47-year-old man presented with rapid deterioration in vision and painful eye movements of his left eye. Two years prior he had been diagnosed frontal demyelinating lesion by MRI biopsy after presenting subacute, though rapidly progressive, right hemiparesis. His neurological deficit worsened despite the treatment intravenous methylprednisolone immunoglobulin, but subsequently responded to rituximab. He was clinically stable over 2 years leading up current presentation, that showed residual...

10.1136/bcr-2016-216239 article EN BMJ Case Reports 2016-09-21

Abstract Introduction Despite the diaphragm being primary muscle involved in respiration, clinical manifestations those with unilateral dysfunction (UDD) are heterogeneous. Though often asymptomatic, UDD can be implicated breathlessness, sleep disordered breathing and hypoventilation. The characteristics of hypoventilation poorly described. We aimed to provide a descriptive analysis patients considered for plication, Methods A audit was performed at tertiary centre providing evaluation...

10.1093/sleepadvances/zpae070.092 article EN cc-by-nc-nd SLEEP Advances 2024-10-01

Introduction: Ultrasound is emerging as a useful tool for the evaluation of immune-mediated neuropathies because it can provide high-resolution anatomic information to complement electrodiagnostic data. Nerve enlargements are commonly found in chronic inflammatory demyelinating polyneuropathy (CIDP), and their presence likely diagnosis, particularly if multifocal. Methods: In this study, authors undertook retrospective chart review identify ultrasound findings patients with CIDP previously...

10.1097/wnp.0000000000000782 article EN Journal of Clinical Neurophysiology 2020-09-28

Previous ultrasonographic studies of individuals with chronic inflammatory demyelinating polyneuropathy (CIDP) have shown nerve enlargement at several sites. This prospective study compares only the bilateral median and ulnar nerves CIDP reference values to determine clinical usefulness this focused approach as a diagnostic tool.The cross-sectional area, echogenicity, vascularity 25 subjects were measured using ultrasound. Nineteen had typical based on European Federation Neurological...

10.1097/wnp.0000000000000905 article EN Journal of Clinical Neurophysiology 2021-10-22

<h3>Objectives</h3> Diagnosis and treatment monitoring in CIDP is primarily based on clinical parameters. High-frequency ultrasound reflects nerve pathophysiology non-invasive painlessly, has been demonstrated as a useful additional diagnostic tool CIDP. However, correlations with disease state response to have mixed. This prospective 12-month study aimed identify potentially prognostic treatment-related biomarkers utilising neuromuscular ultrasound. <h3>Methods</h3> We recruited 35 patients...

10.1136/bmjno-2023-anzan.152 article EN 2023-08-01

Objective: N/A Background: There are no current biomarkers in CIDP, with diagnosis and treatment monitoring largely based on clinical parameters. High frequency ultrasound of peripheral nerves can reflect pathophysiological changes as well treatment, a quick, non-invasive, painless manner. This project aims to further the identification useful diagnostic, prognostic treatment-related utilizing parameters found neuromuscular (NMUS). Design/Methods: We conducted retrospective chart review...

10.1212/wnl.90.15_supplement.p1.340 article EN Neurology 2018-04-10

May 6, 2019April 9, 2019Free AccessA Prospective Study of Patients with Chronic Inflammatory Demyelinating Polyneuropathy (CIDP): Identifying Ultrasonographic Features for Diagnosis and Prognosis (P2.4-001)Nicholas Crump, Michael Cartwright, Richard MacdonellAuthors Info & AffiliationsApril 2019 issue92 (15_supplement)https://doi.org/10.1212/WNL.92.15_supplement.P2.4-001 Letters to the Editor

10.1212/wnl.92.15_supplement.p2.4-001 article EN Neurology 2019-04-09

<h3>Objectives</h3> Diagnosis and treatment monitoring in CIDP is primarily based on clinical parameters. High-frequency ultrasound of peripheral nerves can reflect pathophysiology changes with treatment. This project investigated potential diagnostic prognostic biomarkers utilizing neuromuscular ultrasound. <h3>Methods</h3> We conducted a standardized ultrasonographic assessment 50 patients (25 at WFBMC, 25 Austin), comparing to healthy controls axonal neuropathy subjects. Our protocol...

10.1136/bmjno-2021-anzan.25 article EN 2021-08-01
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