A5064471621- Travel-related health issues
- Heart Failure Treatment and Management
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and healthcare impacts
- Lung Cancer Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Drug-Induced Adverse Reactions
- Respiratory viral infections research
- Emergency and Acute Care Studies
- Mosquito-borne diseases and control
- Influenza Virus Research Studies
- Ultrasound in Clinical Applications
- COVID-19 and Mental Health
- Healthcare professionals’ stress and burnout
- Hepatitis B Virus Studies
- Diabetes Treatment and Management
- Hepatitis Viruses Studies and Epidemiology
- Cardiac, Anesthesia and Surgical Outcomes
- SARS-CoV-2 detection and testing
- Diabetes and associated disorders
- Allergic Rhinitis and Sensitization
- Sepsis Diagnosis and Treatment
- Infection Control and Ventilation
- Viral Infections and Vectors
The Royal Melbourne Hospital
2013-2025
The University of Melbourne
2016-2025
Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine
2025
Medical University of South Carolina
2022-2025
Ralph H. Johnson VA Medical Center
2022-2025
Peter Doherty Institute
2020-2023
Melbourne Health
2020-2023
James Cook University Hospital
2020
Austin Health
2009-2019
Austin Hospital
2008-2018
The coronavirus disease 2019 (COVID-19) pandemic has had a profound and prolonged impact on healthcare services workers.The Australian COVID-19 Frontline Healthcare Workers Study aimed to investigate the severity prevalence of mental health issues, as well social, workplace financial disruptions experienced by workers during pandemic.A nationwide, voluntary, anonymous, single timepoint, online survey was conducted between 27 August 23 October 2020. Individuals self-identifying frontline in...
Multiple sclerosis (MS) is a chronic inflammatory demyelinating and degenerative disease of the central nervous system. There were 33 335 people with MS in Australia 2021 2917 New Zealand 2006 prevalence incidence are increasing time. Although new treatments have substantially improved outcomes recent decades, treatment landscape has become increasingly complex due to expanding number disease-modifying therapies (DMTs) associated safety considerations. A total 80 consensus recommendations...
We assessed the in vivo efficacy of surgical and N95 (respirator) masks to filter reverse transcription-polymerase chain reaction (RT-PCR)-detectable virus when worn correctly by patients with laboratory-confirmed acute influenza. Of 26 a clinical diagnosis influenza, 19 had confirmed RT-PCR, 9 went on complete study. Surgical were equally effective preventing spread PCR-detectable
Abstract : The suggestion by a mediator of point settlement half-way between the positions two negotiators was found to produce substantial concessions. Concessions were also produced high, as opposed low, time pressures; and there more concessions when other negotiator had moved rapidly toward agreement than he slowly. Contrary main hypotheses, effectiveness mediation not function degree pressure or rapidity with which moved. Intervention relieve sense personal inadequacy that otherwise...
The coronavirus disease 2019 (COVID-19) pandemic has significantly impacted the health-care system both in Australia and internationally, rapidly transformed delivery of health care hospitals community. Implementation social isolation distancing measures to stop spread reduce potential harm patients necessitated use alternate models delivery. Changes that would normally take months or years have occurred within days weeks.We conducted analysis outpatient clinic data during period compared...
Robust serological assays are essential for long-term control of the COVID-19 pandemic. Many recently released point-of-care (PoCT) have been distributed with little premarket validation.Performance characteristics 5 PoCT lateral flow devices approved use in Australia were compared to a commercial enzyme immunoassay (ELISA) and described novel surrogate virus neutralization test (sVNT).Sensitivities ranged from 51.8% (95% confidence interval [CI], 43.1%-60.4%) 67.9% CI, 59.4%-75.6%),...
OBJECTIVE Limited studies have examined the association between diabetes and HbA1c with postoperative outcomes. We investigated of diabetes, defined categorically, as a continuous measure, RESEARCH DESIGN AND METHODS In this prospective, observational study, we measured surgical inpatients age ≥54 years at tertiary hospital May 2013 January 2016. Patients were diagnosed if they had preexisting or an ≥6.5% (48 mmol/mol) prediabetes 5.7 6.4% (39 48 mmol/mol). <5.7% categorized having...
Abstract Purpose Denosumab‐associated hypocalcaemia (DAH) has been reported in patients with osteoporosis or metastatic bone disease and is associated stages 4 5 chronic kidney (CKD, estimated glomerular filtration rate <30 mL/min/1.73m 2 ). Other risk factors for have not fully elucidated. We aimed to investigate the incidence of amongst receiving denosumab identify clinical features this adverse event. Methods Retrospective cohort study between June 2013 2014 administered (60/120 mg) at...
Few data exist concerning possible infectious complications associated with endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). The present prospective evaluation was undertaken in order to determine the incidence of bacteraemia and EBUS-TBNA. Consecutive patients undergoing EBUS-TBNA for mediastinal or hilar lymph node lesions were studied. Venesection performed within 60 s TBNA aerobic anaerobic blood culture. Sterile saline washing needles also performed....
Endobronchial ultrasound (EBUS) transbronchial needle aspiration (TBNA) is an important diagnostic procedure for the interrogation of mediastinal lymph nodes. There limited data describing accuracy & safety this technique diagnosis tuberculous lymphadenitis.A multi-centre retrospective study all EBUS-guided TBNA procedures that referred samples mycobacteriology was performed. Results were correlated with post-procedural diagnoses after a period surveillance and cross-checked against relevant...
Journal Article L'Opium des Intellectuels Get access Intellectuels. By Raymond Aron. Paris, Calmann-Lévy, 1955. 337 pp. 8¼″. × 5½″. Frs. 750. Douglas Johnson Search for other works by this author on: Oxford Academic Google Scholar International Affairs, Volume 32, Issue 1, January 1956, Page 69, https://doi.org/10.2307/2607816 Published: 01 1956
General physicians as system leaders play a significant role in quality improvement (QI) initiatives within respective health services. However, there are very few formal QI training programmes available for general Australia. This survey described the experiences of attendees at 2024 Internal Medicine Society Australia and New Zealand workshop, which delivered topics on understanding variations healthcare data using tools such run charts statistical process control (Shewhart) charts.
Multiple sclerosis (MS) is a chronic inflammatory and neurodegenerative disease of the central nervous system with rapidly evolving treatment options strategies. An iterative modified Delphi process was used to develop 80 consensus recommendations for management MS in Australia New Zealand. Part 1 these guidelines includes related selection initial disease-modifying therapy (DMT) MS, assessments before commencing DMT, monitoring activity on switching discontinuing DMT. This article, 2,...
Hospitalised, unwell patients have vital signs such as heart rate (HR), oxygen saturation (SpO2) and temperature measured multiple times a day to detect clinical deterioration monitor health trajectories. Advancements in contact-free (ambient) sensors (AS) measure can help mitigate risks due skin injury infection transmission seen conventional hospital equipment. This prospective, observational study aims validate sign measurements from multi-channel AS compared equipment three cohorts:...
Importance Antibiotic allergy labels (AALs) impact patient health and perioperative outcomes. delabeling could improve antibiotic prescribing infection-related outcomes perioperatively. Objective To assess the feasibility safety of assessment in anesthesiologist-led preoperative clinics expand efforts outside specialist clinics. Design, Setting, Participants This randomized clinical trial was a multicenter, phase 2 conducted between December 14, 2020, October 31, 2023, at outpatient 3...
Abstract Objectives Chronic cannabis use is linked to anti-inflammatory effects, and cocaine exhibits context-dependent immunomodulation; their distinct impacts on monocyte subsets systemic inflammation are not fully understood. Systemic microbial translocation contributes differentiation, but the levels in chronic users humans vivo lacking. Methods Peripheral blood mononuclear cells (PBMCs) plasma samples were collected from users, non-drug users. The route of drug administration was via...
Mannose-binding lectin (MBL) is an important mediator of innate immunity and synthesized primarily by the liver. Low MBL levels are common, due to polymorphisms in gene encoding (MBL2), associated with increased risk infection, particularly when compromised. We report a large, retrospective study that examined association between status clinically significant infection following orthotopic liver transplantation.One hundred two donor-recipient transplantation pairs were studied. Five promoter...
Although many studies provide strong evidence supporting the development of HCV virus-like particle (VLP)-based vaccines, fact that heterologous viral vectors and/or multiple dosing regimes are required to induce protective immunity indicates it is necessary improve their immunogenicity. In this study, we have evaluated use an anionic self-adjuvanting lipopeptide containing TLR2 agonist Pam2Cys (E8Pam2Cys) enhance immunogenicity VLPs structural proteins (core, E1 and E2) genotype 1a. While...
To determine the nature, prevalence and description accuracy of recorded antibiotic allergy labels (AALs) in a cohort general medical inpatients, to assess feasibility an oral re-challenge study.Multicentre cross-sectional study.All patients admitted units Austin Health Alfred Health, 18 May - 5 June 2015.Baseline demographics, history, infection diagnoses prescribing data for inpatients were collected. A questionnaire was administered clarify AAL followed by correlation responses with...
To design and evaluate 3D-printed nasal swabs for collection of samples SARS-CoV-2 testing. An iterative process was employed. Laboratory evaluation included in vitro assessment mock nasopharyngeal spiked with two different concentrations gamma-irradiated SARS-CoV-2. A prospective clinical study compared human cellular material recovery by standard swabs. Royal Melbourne Hospital, May 2020. Participants the were 50 hospital staff members attending a COVID-19 screening clinic inpatients...